Matthew L. Eaton, Ph.D.
Affiliations: | 2011 | Computational Biology and Bioinformatics | Duke University, Durham, NC |
Area:
Bioinformatics, Molecular Biology, Computer Science, GeneticsGoogle:
"Matthew Eaton"Parents
Sign in to add mentor| David M. MacAlpine | grad student | 2011 | Duke | |
| (Chromatin Determinants of the Eukaryotic DNA Replication Program.) | ||||
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Publications
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| Lee H, McManus CJ, Cho DY, et al. (2019) Correction to: DNA copy number evolution in Drosophila cell lines. Genome Biology. 20: 53 |
| Guenther M, Lambert A, Chen M, et al. (2018) Abstract P2-04-03: Epigenomic analysis of cancer stem cell (CSC)-enriched triple-negative breast cancer (TNBC) populations reveals gene regulatory circuitry and novel tumor cell vulnerabilities Cancer Research. 78 |
| McKeown MR, Corces MR, Eaton ML, et al. (2017) Super-Enhancer Analysis Defines Novel Epigenomic Subtypes of Non-APL AML Including an RARα Dependency Targetable by SY-1425, a Potent and Selective RARα Agonist. Cancer Discovery |
| Fiore CM, McKeown MR, Lee E, et al. (2017) Abstract PR05: SY-1425 (tamibarotene), a potent and selective RARα agonist, induces changes in the transcriptional regulatory circuit of AML cells leading to differentiation Clinical Cancer Research. 23 |
| McKeown, Fiore C, Lee E, et al. (2017) Abstract P6-11-18: A novel subgroup of estrogen receptor positive breast cancer may benefit from super-enhancer guided patient selection for retinoic acid receptor α agonist treatment Cancer Research. 77 |
| McKeown MR, Lee E, Fiore C, et al. (2017) Abstract 3085: SY-1425 (tamibarotene), a selective RARα agonist, shows synergistic anti-tumor activity with hypomethylating agents in a biomarker selected subset of AML Cancer Research. 77: 3085-3085 |
| McKeown MR, Eaton ML, Fiore C, et al. (2017) Abstract 1511: AML patient clustering by super-enhancers reveals an RARA associated transcription factor signaling partner Cancer Research. 77: 1511-1511 |
| Feng J, Gan H, Eaton ML, et al. (2016) Non-coding transcription is a driving force for nucleosome instability in spt16 mutant cells. Molecular and Cellular Biology |
| McKeown MR, Fiore C, Lee E, et al. (2016) Clinical Pharmacodynamic Markers and Combinations with SY1425 (tamibarotene) in a Genomically-Defined Subset of Non-APL AML Blood. 128: 2898-2898 |
| Fiore C, McKeown MR, Lee E, et al. (2016) SY1425 (tamibarotene) Induces Profound Transcriptional Changes in AML Tumors with High Retinoic Acid Receptor Alpha Blood. 128: 1523-1523 |