Karen E. Ocwieja, Ph.D.

Affiliations: 
2012 Cell and Molecular Biology University of Pennsylvania, Philadelphia, PA, United States 
Area:
Bioinformatics, Molecular Biology, Immunology
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"Karen Ocwieja"

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Frederic D. Bushman grad student 2012 Penn
 (Patterns of HIV integration and splicing: Windows on mechanism.)
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Publications

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Ocwieja K, Stanton A, Richards A, et al. (2019) 973. Single-cell RNA Sequencing Analysis of Zika Virus Infection in Human Stem Cell-Derived Cerebral Organoids Open Forum Infectious Diseases. 6: S33-S34
Gijsbers R, Vets S, De Rijck J, et al. (2018) Role of the PWWP domain of lens epithelium-derived growth factor (LEDGF)/p75 cofactor in lentiviral integration targeting. The Journal of Biological Chemistry. 293: 114
Sherrill-Mix S, Ocwieja KE, Bushman FD. (2015) Gene activity in primary T cells infected with HIV89.6: intron retention and induction of genomic repeats. Retrovirology. 12: 79
Ocwieja KE, Sherrill-Mix S, Liu C, et al. (2015) A reverse transcription loop-mediated isothermal amplification assay optimized to detect multiple HIV subtypes. Plos One. 10: e0117852
Berry CC, Ocwieja KE, Malani N, et al. (2014) Comparing DNA integration site clusters with scan statistics. Bioinformatics (Oxford, England). 30: 1493-500
Sherrill-Mix S, Lewinski MK, Famiglietti M, et al. (2013) HIV latency and integration site placement in five cell-based models. Retrovirology. 10: 90
Ocwieja KE, Sherrill-Mix S, Mukherjee R, et al. (2012) Dynamic regulation of HIV-1 mRNA populations analyzed by single-molecule enrichment and long-read sequencing. Nucleic Acids Research. 40: 10345-55
Bushman FD, Brady T, Malani N, et al. (2012) 134 HIV DNA Integration Jaids Journal of Acquired Immune Deficiency Syndromes. 59: 55
Schaller T, Ocwieja KE, Rasaiyaah J, et al. (2011) HIV-1 capsid-cyclophilin interactions determine nuclear import pathway, integration targeting and replication efficiency Plos Pathogens. 7
Gijsbers R, Vets S, De Rijck J, et al. (2011) Role of the PWWP domain of lens epithelium-derived growth factor (LEDGF)/p75 cofactor in lentiviral integration targeting. The Journal of Biological Chemistry. 286: 41812-25
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