David Garfinkel, Ph.D.
Affiliations: | Computer Science | University of Pennsylvania, Philadelphia, PA, United States |
Area:
metabolic modeling, numerical solution of nonlinear ODEsGoogle:
"David Garfinkel"Bio:
worked with Benno Hess and Britton Chance
Used both analog and digital computers.
Worked on solution of stiff ODEs.
Large-scale models of glycolysis and TCA cycle with Michael Kohn.
Deceased 1990
Cross-listing: MathTree
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Publications
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| Garfinkel D, Ching SW, Adelman M, et al. (2006) Techniques and problems in the construction of computer models of biochemical systems including real enzymes. Annals of the New York Academy of Sciences. 128: 1054-1068 |
| Achs MJ, Garfinkel L, Garfinkel D. (1991) A computer model of pancreatic islet glycolysis. Journal of Theoretical Biology. 150: 109-35 |
| Garfinkel L, Cohen DM, Soo VW, et al. (1989) An artificial-intelligence technique for qualitatively deriving enzyme kinetic mechanisms from initial-velocity measurements and its application to hexokinase. The Biochemical Journal. 264: 175-84 |
| Garfinkel D. (1989) Constraint matching as a means of designing biochemical experiments in multi-enzyme systems. Journal of Theoretical Biology. 137: 221-34 |
| Soo VW, Kulikowski CA, Garfinkel D, et al. (1988) Theory formation in postulating enzyme kinetic mechanisms: reasoning with constraints. Computers and Biomedical Research, An International Journal. 21: 381-403 |
| Achs MJ, Garfinkel D. (1988) Pancreatic islet discrimination of hexose anomers. II. Transient computer simulation. The American Journal of Physiology. 255: E201-5 |
| Achs MJ, Garfinkel D. (1988) Pancreatic islet discrimination of hexose anomers. I. Steady-state computer simulation. The American Journal of Physiology. 255: E189-200 |
| Garfinkel L, Garfinkel D, Matsiras P, et al. (1987) Kinetic properties of hexokinase as assembled with a microcomputer data base. The Biochemical Journal. 244: 351-7 |
| Schremmer SD, Waser MR, Kohn MC, et al. (1984) A computer program for analyzing enzyme kinetic data using graphical display and statistical analysis. Computers and Biomedical Research, An International Journal. 17: 289-301 |
| Kohn MC, Garfinkel D. (1983) Computer simulation of metabolism in palmitate-perfused rat heart. I. Palmitate oxidation Annals of Biomedical Engineering. 11: 361-384 |