Kevin D. Costa, Ph.D.
Affiliations: | Bioengineering | University of California, San Diego, La Jolla, CA |
Area:
cardiac biomechanics, tissue engineering, atomic force microscopyGoogle:
"Kevin Costa"Children
Sign in to add trainee| Jia Jye Lee | grad student | Mount Sinai School of Medicine | |
| Eun Jung Lee | grad student | 2007 | Columbia |
| Evren U. Azeloglu | grad student | 2009 | Columbia |
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Publications
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| Wong AO, Wong N, Geng L, et al. (2020) Combinatorial Treatment of Human Cardiac Engineered Tissues With Biomimetic Cues Induces Functional Maturation as Revealed by Optical Mapping of Action Potentials and Calcium Transients. Frontiers in Physiology. 11: 165 |
| Keung W, Chan PK, Backeris P, et al. (2019) Human cardiac ventricular organoid chambers and tissue strips from pluripotent stem cells as a two-tiered assay for inotropic responses: A blinded validation. Journal of Pharmacological and Toxicological Methods. 99: 106595 |
| Wong AO, Lieu DK, Wong GK, et al. (2019) Modeling cardiac dysfunction of Friedreich's ataxia using ventricular sheets, tissues and chambers engineered from human pluripotent stem cells. Journal of Pharmacological and Toxicological Methods. 99: 106595 |
| Shum A, Wong AO, Chan CW, et al. (2019) Directly visualizing drug-induced arrhythmias with aligned human pluripotent stem cell-based ventricular cardiac anisotropic sheet. Journal of Pharmacological and Toxicological Methods. 99: 106595 |
| Lee EK, Tran DD, Keung W, et al. (2019) Automated drug classification by machine learning analysis of drug screening data from human pluripotent stem cell-derived engineered cardiac tissue assays. Journal of Pharmacological and Toxicological Methods. 99: 106595 |
| Li RA, Keung W, Cashman T, et al. (2019) "Human heart-in-a-Jar": An electro-mechanically functional miniature ventricular heart chamber from human pluripotent stem cells. Journal of Pharmacological and Toxicological Methods. 99: 106595 |
| Wong AO, Chan CW, Costa KD, et al. (2019) Controlled physiomimetic preload augments inotropic sensitivity and contractile phenotypes in human pluripotent stem cell-derived engineered cardiac tissues and chambers. Journal of Pharmacological and Toxicological Methods. 99: 106595 |
| Murphy JF, Mayourian J, Stillitano F, et al. (2019) Adult human cardiac stem cell supplementation effectively increases contractile function and maturation in human engineered cardiac tissues. Stem Cell Research & Therapy. 10: 373 |
| Wong AO, Wong G, Shen M, et al. (2019) Correlation between frataxin expression and contractility revealed by in vitro Friedreich's ataxia cardiac tissue models engineered from human pluripotent stem cells. Stem Cell Research & Therapy. 10: 203 |
| Chow MZ, Sadrian SN, Keung W, et al. (2019) Modulation of chromatin remodeling proteins SMYD1 and SMARCD1 promotes contractile function of human pluripotent stem cell-derived ventricular cardiomyocyte in 3D-engineered cardiac tissues. Scientific Reports. 9: 7502 |