Takashi Ochi, Ph.D.
Affiliations: | 2018- | Astbury Centre for Structural Molecular Biology | University of Leeds, Leeds, England, United Kingdom |
Area:
Structure BiologyWebsite:
https://ochilab.org/Google:
"Takashi Ochi"Children
Sign in to add trainee| Hira Khan | grad student | 2019- | University of Leeds |
| Isha Mohan | grad student | 2021- | University of Leeds |
| Emma Wood | grad student | 2023- | University of Leeds |
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Publications
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| Khan H, Ochi T. (2023) Plant PAXX has an XLF-like function and stimulates DNA end joining by the Ku-DNA ligase IV/XRCC4 complex. The Plant Journal : For Cell and Molecular Biology |
| Goff NJ, Brenière M, Buehl CJ, et al. (2022) Catalytically inactive DNA ligase IV promotes DNA repair in living cells. Nucleic Acids Research |
| Ochi T, Quarantotti V, Lin H, et al. (2020) CCDC61/VFL3 Is a Paralog of SAS6 and Promotes Ciliary Functions. Structure (London, England : 1993) |
| Wu Q, Liang S, Ochi T, et al. (2019) Understanding the structure and role of DNA-PK in NHEJ: How X-ray diffraction and cryo-EM contribute in complementary ways. Progress in Biophysics and Molecular Biology |
| Wang JL, Duboc C, Wu Q, et al. (2018) Dissection of DNA double-strand-break repair using novel single-molecule forceps. Nature Structural & Molecular Biology |
| Chang HH, Watanabe G, Gerodimos CA, et al. (2016) Different DNA End Configurations Dictate Which NHEJ Components are Most Important for Joining Efficiency. The Journal of Biological Chemistry |
| Wu Q, Paul A, Su D, et al. (2016) Structure of BRCA1-BRCT/Abraxas Complex Reveals Phosphorylation-Dependent BRCT Dimerization at DNA Damage Sites. Molecular Cell |
| Liang S, Esswein SR, Ochi T, et al. (2016) Achieving selectivity in space and time with DNA double-strand-break response and repair: molecular stages and scaffolds come with strings attached Structural Chemistry. 28: 161-171 |
| Murray JE, van der Burg M, IJspeert H, et al. (2015) Mutations in the NHEJ component XRCC4 cause primordial dwarfism. American Journal of Human Genetics. 96: 412-24 |
| Ochi T, Blackford AN, Coates J, et al. (2015) DNA repair. PAXX, a paralog of XRCC4 and XLF, interacts with Ku to promote DNA double-strand break repair. Science (New York, N.Y.). 347: 185-8 |