Jose Davila-Velderrain

Affiliations: 
Massachusetts Institute of Technology, Cambridge, MA, United States 
Area:
Computational biology, systems biology, neurogenomics
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"Jose Davila-Velderrain"
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Publications

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Huang WC, Peng Z, Murdock MH, et al. (2023) Lateral mammillary body neurons in mouse brain are disproportionately vulnerable in Alzheimer's disease. Science Translational Medicine. 15: eabq1019
Blanchard JW, Akay LA, Davila-Velderrain J, et al. (2022) APOE4 impairs myelination via cholesterol dysregulation in oligodendrocytes. Nature
Welch GM, Boix CA, Schmauch E, et al. (2022) Neurons burdened by DNA double-strand breaks incite microglia activation through antiviral-like signaling in neurodegeneration. Science Advances. 8: eabo4662
Singh N, Benoit MR, Zhou J, et al. (2022) BACE-1 inhibition facilitates the transition from homeostatic microglia to DAM-1. Science Advances. 8: eabo1286
Barker SJ, Raju RM, Milman NEP, et al. (2021) MEF2 is a key regulator of cognitive potential and confers resilience to neurodegeneration. Science Translational Medicine. 13: eabd7695
He L, Davila-Velderrain J, Sumida TS, et al. (2021) NEBULA is a fast negative binomial mixed model for differential or co-expression analysis of large-scale multi-subject single-cell data. Communications Biology. 4: 629
Blanchard JW, Bula M, Davila-Velderrain J, et al. (2021) Author Correction: Reconstruction of the human blood-brain barrier in vitro reveals a pathogenic mechanism of APOE4 in pericytes. Nature Medicine
Mohammadi S, Davila-Velderrain J, Kellis M. (2020) A multiresolution framework to characterize single-cell state landscapes. Nature Communications. 11: 5399
Marco A, Meharena HS, Dileep V, et al. (2020) Mapping the epigenomic and transcriptomic interplay during memory formation and recall in the hippocampal engram ensemble. Nature Neuroscience
Lee H, Fenster RJ, Pineda SS, et al. (2020) Cell Type-Specific Transcriptomics Reveals that Mutant Huntingtin Leads to Mitochondrial RNA Release and Neuronal Innate Immune Activation. Neuron
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