Jose Davila-Velderrain

Affiliations: 
Massachusetts Institute of Technology, Cambridge, MA, United States 
Area:
Computational biology, systems biology, neurogenomics
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"Jose Davila-Velderrain"
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Publications

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Mathys H, Boix CA, Akay LA, et al. (2024) Single-cell multiregion dissection of Alzheimer's disease. Nature
Ruzicka WB, Mohammadi S, Fullard JF, et al. (2024) Single-cell multi-cohort dissection of the schizophrenia transcriptome. Science (New York, N.Y.). 384: eadg5136
Huang WC, Peng Z, Murdock MH, et al. (2023) Lateral mammillary body neurons in mouse brain are disproportionately vulnerable in Alzheimer's disease. Science Translational Medicine. 15: eabq1019
Blanchard JW, Akay LA, Davila-Velderrain J, et al. (2022) APOE4 impairs myelination via cholesterol dysregulation in oligodendrocytes. Nature
Welch GM, Boix CA, Schmauch E, et al. (2022) Neurons burdened by DNA double-strand breaks incite microglia activation through antiviral-like signaling in neurodegeneration. Science Advances. 8: eabo4662
Singh N, Benoit MR, Zhou J, et al. (2022) BACE-1 inhibition facilitates the transition from homeostatic microglia to DAM-1. Science Advances. 8: eabo1286
Barker SJ, Raju RM, Milman NEP, et al. (2021) MEF2 is a key regulator of cognitive potential and confers resilience to neurodegeneration. Science Translational Medicine. 13: eabd7695
He L, Davila-Velderrain J, Sumida TS, et al. (2021) NEBULA is a fast negative binomial mixed model for differential or co-expression analysis of large-scale multi-subject single-cell data. Communications Biology. 4: 629
Blanchard JW, Bula M, Davila-Velderrain J, et al. (2021) Author Correction: Reconstruction of the human blood-brain barrier in vitro reveals a pathogenic mechanism of APOE4 in pericytes. Nature Medicine
Mohammadi S, Davila-Velderrain J, Kellis M. (2020) A multiresolution framework to characterize single-cell state landscapes. Nature Communications. 11: 5399
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