Robert A Craigie

Affiliations: 
Molecular Virology section NIH (NIDDK) 
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"Robert Craigie"
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Li M, Li Z, Chen X, et al. (2024) HIV-1 Intasomes Assembled with Excess Integrase C-Terminal Domain Protein Facilitate Structural Studies by Cryo-EM and Reveal the Role of the Integrase C-Terminal Tail in HIV-1 Integration. Viruses. 16
Li M, Yang R, Chen X, et al. (2024) HIV-1 integrase assembles multiple species of stable synaptic complex intasomes that are active for concerted DNA integration in vitro. Journal of Molecular Biology. 168557
Mahajan PS, Smith SJ, Li M, et al. (2024) -Substituted Bicyclic Carbamoyl Pyridones: Integrase Strand Transfer Inhibitors that Potently Inhibit Drug-Resistant HIV-1 Integrase Mutants. Acs Infectious Diseases
Jing T, Shan Z, Dinh T, et al. (2024) Oligomeric HIV-1 Integrase Structures Reveal Functional Plasticity for Intasome Assembly and RNA Binding. Biorxiv : the Preprint Server For Biology
Li M, Oliveira Passos D, Shan Z, et al. (2023) Mechanisms of HIV-1 integrase resistance to dolutegravir and potent inhibition of drug-resistant variants. Science Advances. 9: eadg5953
Sapp N, Burge N, Cox K, et al. (2022) HIV-1 Preintegration Complex Preferentially Integrates the Viral DNA into Nucleosomes Containing Trimethylated Histone 3-Lysine 36 Modification and Flanking Linker DNA. Journal of Virology. e0101122
Passos DO, Li M, Craigie R, et al. (2021) Retroviral integrase: Structure, mechanism, and inhibition. The Enzymes. 50: 249-300
Davids BO, Balasubramaniam M, Sapp N, et al. (2021) Human Three Prime Repair Exonuclease 1 Promotes HIV-1 Integration by Preferentially Degrading Unprocessed Viral DNA. Journal of Virology. JVI0055521
Craigie R. (2021) The molecular biology of HIV integrase. Future Virology. 7: 679-686
Li M, Chen X, Wang H, et al. (2020) A peptide derived from lens epithelium-derived growth factor stimulates HIV-1 DNA integration and facilitates intasome structural studies. Journal of Molecular Biology
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