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Vinod Ganapathy, Ph.D. - Publications

Affiliations: 
2007 University of Wisconsin, Madison, Madison, WI 
Area:
Computer Science
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Year Citation  Score
2017 Sivaprakasam S, Bhutia YD, Yang S, Ganapathy V. Short-Chain Fatty Acid Transporters: Role in Colonic Homeostasis. Comprehensive Physiology. 8: 299-314. PMID 29357130 DOI: 10.1002/Cphy.C170014  0.303
2015 Bhutia YD, Ganapathy V. Glutamine transporters in mammalian cells and their functions in physiology and cancer. Biochimica Et Biophysica Acta. PMID 26724577 DOI: 10.1016/J.Bbamcr.2015.12.017  0.316
2015 Bhutia YD, Ganapathy V. A novel tryptophan-selective amino acid transporter that is functionally coupled to ido1-dependent signaling pathways New Developments in Tryptophan Research. 143-154.  0.309
2010 Miyauchi S, Gopal E, Babu E, Srinivas SR, Kubo Y, Umapathy NS, Thakkar SV, Ganapathy V, Prasad PD. Sodium-coupled electrogenic transport of pyroglutamate (5-oxoproline) via SLC5A8, a monocarboxylate transporter. Biochimica Et Biophysica Acta. 1798: 1164-71. PMID 20211600 DOI: 10.1016/J.Bbamem.2010.03.002  0.304
2009 Anderson CM, Howard A, Walters JR, Ganapathy V, Thwaites DT. Taurine uptake across the human intestinal brush-border membrane is via two transporters: H+-coupled PAT1 (SLC36A1) and Na+- and Cl(-)-dependent TauT (SLC6A6). The Journal of Physiology. 587: 731-44. PMID 19074966 DOI: 10.1113/Jphysiol.2008.164228  0.302
2008 Ganapathy V, Thangaraju M, Gopal E, Martin PM, Itagaki S, Miyauchi S, Prasad PD. Sodium-coupled monocarboxylate transporters in normal tissues and in cancer. The Aaps Journal. 10: 193-9. PMID 18446519 DOI: 10.1208/S12248-008-9022-Y  0.303
2006 Miyauchi S, Srinivas SR, Fei YJ, Gopal E, Umapathy NS, Wang H, Conway SJ, Ganapathy V, Prasad PD. Functional Characteristics of NaS2, a Placenta-specific Na+-coupled Transporter for Sulfate and Oxyanions of the Micronutrients Selenium and Chromium Placenta. 27: 550-559. PMID 16129486 DOI: 10.1016/J.Placenta.2005.05.004  0.307
2004 Inoue K, Fei YJ, Zhuang L, Gopal E, Miyauchi S, Ganapathy V. Functional features and genomic organization of mouse NaCT, a sodium-coupled transporter for tricarboxylic acid cycle intermediates. The Biochemical Journal. 378: 949-57. PMID 14656221 DOI: 10.1042/Bj20031261  0.305
2003 Naggar H, Fei YJ, Ganapathy V, Smith SB. Regulation of reduced-folate transporter-1 (RFT-1) by homocysteine and identity of transport systems for homocysteine uptake in retinal pigment epithelial (RPE) cells. Experimental Eye Research. 77: 687-97. PMID 14609557 DOI: 10.1016/J.Exer.2003.08.013  0.307
2003 Chen Z, Fei YJ, Anderson CM, Wake KA, Miyauchi S, Huang W, Thwaites DT, Ganapathy V. Structure, function and immunolocalization of a proton-coupled amino acid transporter (hPAT1) in the human intestinal cell line Caco-2. The Journal of Physiology. 546: 349-61. PMID 12527723 DOI: 10.1113/Jphysiol.2002.026500  0.303
2003 Inoue K, Zhuang L, Ganapathy V. Human Na+ -coupled citrate transporter: primary structure, genomic organization, and transport function. Biochemical and Biophysical Research Communications. 299: 465-71. PMID 12445824 DOI: 10.1016/S0006-291X(02)02669-4  0.314
2001 Nakanishi T, Hatanaka T, Huang W, Prasad PD, Leibach FH, Ganapathy ME, Ganapathy V. Na+- and Cl--coupled active transport of carnitine by the amino acid transporter ATB(0,+) from mouse colon expressed in HRPE cells and Xenopus oocytes. The Journal of Physiology. 532: 297-304. PMID 11306651 DOI: 10.1111/J.1469-7793.2001.0297F.X  0.317
2000 Wang H, Huang W, Sugawara M, Devoe LD, Leibach FH, Prasad PD, Ganapathy V. Cloning and functional expression of ATA1, a subtype of amino acid transporter A, from human placenta. Biochemical and Biophysical Research Communications. 273: 1175-9. PMID 10891391 DOI: 10.1006/Bbrc.2000.3061  0.302
2000 Fei YJ, Sugawara M, Nakanishi T, Huang W, Wang H, Prasad PD, Leibach FH, Ganapathy V. Primary structure, genomic organization, and functional and electrogenic characteristics of human system N 1, a Na+- and H+-coupled glutamine transporter. The Journal of Biological Chemistry. 275: 23707-17. PMID 10823827 DOI: 10.1074/Jbc.M002282200  0.315
1999 Dutta B, Huang W, Molero M, Kekuda R, Leibach FH, Devoe LD, Ganapathy V, Prasad PD. Cloning of the human thiamine transporter, a member of the folate transporter family. The Journal of Biological Chemistry. 274: 31925-9. PMID 10542220 DOI: 10.1074/Jbc.274.45.31925  0.305
1999 Prasad PD, Wang H, Huang W, Fei YJ, Leibach FH, Devoe LD, Ganapathy V. Molecular and functional characterization of the intestinal Na+-dependent multivitamin transporter. Archives of Biochemistry and Biophysics. 366: 95-106. PMID 10334869 DOI: 10.1006/Abbi.1999.1213  0.304
1998 Prasad PD, Wang H, Kekuda R, Fujita T, Fei YJ, Devoe LD, Leibach FH, Ganapathy V. Cloning and functional expression of a cDNA encoding a mammalian sodium-dependent vitamin transporter mediating the uptake of pantothenate, biotin, and lipoate. The Journal of Biological Chemistry. 273: 7501-6. PMID 9516450 DOI: 10.1074/Jbc.273.13.7501  0.303
1995 Ganapathy V, Ramamoorthy JD, Del Monte MA, Leibach FH, Ramamoorthy S. Cyclic AMP-dependent up-regulation of the taurine transporter in a human retinal pigment epithelial cell line Current Eye Research. 14: 843-850. PMID 8529424 DOI: 10.3109/02713689508995807  0.307
1995 Jayanthi LD, Ramamoorthy S, Mahesh VB, Leibach FH, Ganapathy V. Substrate-specific regulation of the taurine transporter in human placental choriocarcinoma cells (JAR). Biochimica Et Biophysica Acta. 1235: 351-60. PMID 7756345 DOI: 10.1016/0005-2736(95)80024-A  0.301
1994 Liu W, Leibach FH, Ganapathy V. Characterization of the glycine transport system GLYT 1 in human placental choriocarcinoma cells (JAR). Biochimica Et Biophysica Acta. 1194: 176-84. PMID 8075134 DOI: 10.1016/0005-2736(94)90218-6  0.304
1994 Ramamoorthy S, Del Monte MA, Leibach FH, Ganapathy V. Molecular identity and calmodulin-mediated regulation of the taurine transporter in a human retinal pigment epithelial cell line Current Eye Research. 13: 523-529. PMID 7924416 DOI: 10.3109/02713689408999884  0.313
1994 Ganapathy V, Leibach FH. Expression and regulation of the taurine transporter in cultured cell lines of human origin Advances in Experimental Medicine and Biology. 359: 51-57. PMID 7887288 DOI: 10.1007/978-1-4899-1471-2_6  0.31
Low-probability matches (unlikely to be authored by this person)
1996 Prasad PD, Hoffmans BJ, Moe AJ, Smith CH, Leibach FH, Ganapathy V. Functional expression of the plasma membrane serotonin transporter but not the vesicular monoamine transporter in human placental trophoblasts and choriocarcinoma cells. Placenta. 17: 201-7. PMID 8761963 DOI: 10.1016/S0143-4004(96)90039-9  0.299
1994 Prasad PD, Mahesh VB, Leibach FH, Ganapathy V. Functional coupling between a bafilomycin A1-sensitive proton pump and a probenecid-sensitive folate transporter in human placental choriocarcinoma cells. Biochimica Et Biophysica Acta. 1222: 309-14. PMID 8031869 DOI: 10.1016/0167-4889(94)90184-8  0.299
1999 Rajan DP, Huang W, Dutta B, Devoe LD, Leibach FH, Ganapathy V, Prasad PD. Human placental sodium-dependent vitamin C transporter (SVCT2): molecular cloning and transport function. Biochemical and Biophysical Research Communications. 262: 762-8. PMID 10471399 DOI: 10.1006/Bbrc.1999.1272  0.298
2011 Chothe P, Singh N, Ganapathy V. Evidence for two different broad-specificity oligopeptide transporters in intestinal cell line Caco-2 and colonic cell line CCD841. American Journal of Physiology. Cell Physiology. 300: C1260-9. PMID 21307350 DOI: 10.1152/Ajpcell.00299.2010  0.298
2007 Gopal E, Umapathy NS, Martin PM, Ananth S, Gnana-Prakasam JP, Becker H, Wagner CA, Ganapathy V, Prasad PD. Cloning and functional characterization of human SMCT2 (SLC5A12) and expression pattern of the transporter in kidney. Biochimica Et Biophysica Acta. 1768: 2690-7. PMID 17692818 DOI: 10.1016/J.Bbamem.2007.06.031  0.297
2004 Gopal E, Fei YJ, Sugawara M, Miyauchi S, Zhuang L, Martin P, Smith SB, Prasad PD, Ganapathy V. Expression of slc5a8 in kidney and its role in Na(+)-coupled transport of lactate. The Journal of Biological Chemistry. 279: 44522-32. PMID 15322102 DOI: 10.1074/Jbc.M405365200  0.296
2007 Srinivas SR, Prasad PD, Umapathy NS, Ganapathy V, Shekhawat PS. Transport of butyryl-L-carnitine, a potential prodrug, via the carnitine transporter OCTN2 and the amino acid transporter ATB(0,+). American Journal of Physiology. Gastrointestinal and Liver Physiology. 293: G1046-53. PMID 17855766 DOI: 10.1152/Ajpgi.00233.2007  0.295
1998 Kekuda R, Prasad PD, Wu X, Wang H, Fei YJ, Leibach FH, Ganapathy V. Cloning and functional characterization of a potential-sensitive, polyspecific organic cation transporter (OCT3) most abundantly expressed in placenta. The Journal of Biological Chemistry. 273: 15971-9. PMID 9632645 DOI: 10.1074/Jbc.273.26.15971  0.295
1997 Kekuda R, Leibach FH, Ganapathy V. Tyrosine phosphorylation-and epidermal growth factor-dependent regulation of the sodium-coupled amino acid transporter B0 in the human placental choriocarcinoma cell line JAR. Biochimica Et Biophysica Acta. 1356: 258-70. PMID 9194569 DOI: 10.1016/S0167-4889(96)00178-4  0.295
2009 Ganapathy V, Thangaraju M, Prasad PD. Nutrient transporters in cancer: relevance to Warburg hypothesis and beyond. Pharmacology & Therapeutics. 121: 29-40. PMID 18992769 DOI: 10.1016/J.Pharmthera.2008.09.005  0.294
1991 Kulanthaivel P, Cool DR, Ramamoorthy S, Mahesh VB, Leibach FH, Ganapathy V. Transport of taurine and its regulation by protein kinase C in the JAR human placental choriocarcinoma cell line. The Biochemical Journal. 277: 53-8. PMID 1854347 DOI: 10.1042/Bj2770053  0.294
2006 Seymour RL, Ganapathy V, Mellor AL, Munn DH. A high-affinity, tryptophan-selective amino acid transport system in human macrophages. Journal of Leukocyte Biology. 80: 1320-7. PMID 16997853 DOI: 10.1189/Jlb.1205727  0.293
2017 Sikder MOF, Yang S, Ganapathy V, Bhutia YD. The Na+/Cl--Coupled, Broad-Specific, Amino Acid Transporter SLC6A14 (ATB0,+): Emerging Roles in Multiple Diseases and Therapeutic Potential for Treatment and Diagnosis. The Aaps Journal. 20: 12. PMID 29204754 DOI: 10.1208/S12248-017-0164-7  0.293
2001 Bridges CC, Ola MS, Prasad PD, El-Sherbeny A, Ganapathy V, Smith SB. Regulation of taurine transporter expression by NO in cultured human retinal pigment epithelial cells. American Journal of Physiology. Cell Physiology. 281: C1825-36. PMID 11698241 DOI: 10.1152/Ajpcell.2001.281.6.C1825  0.293
2004 Hatanaka T, Haramura M, Fei YJ, Miyauchi S, Bridges CC, Ganapathy PS, Smith SB, Ganapathy V, Ganapathy ME. Transport of amino acid-based prodrugs by the Na+- and Cl(-) -coupled amino acid transporter ATB0,+ and expression of the transporter in tissues amenable for drug delivery. The Journal of Pharmacology and Experimental Therapeutics. 308: 1138-47. PMID 14617696 DOI: 10.1124/Jpet.103.057109  0.293
1977 Prasad PD, Ramamoorthy S, Leibach FH, Ganapathy V. Characterization of a sodium-dependent vitamin transporter mediating the uptake of pantothenate, biotin and lipoate in human placental choriocarcinoma cells Placenta. 18: 527-533. PMID 9290147 DOI: 10.1016/0143-4004(77)90006-6  0.293
1995 Fei YJ, Prasad PD, Leibach FH, Ganapathy V. The amino acid transport system y+L induced in Xenopus laevis oocytes by human choriocarcinoma cell (JAR) mRNA is functionally related to the heavy chain of the 4F2 cell surface antigen. Biochemistry. 34: 8744-51. PMID 7612614 DOI: 10.1021/Bi00027A025  0.293
2008 Talukder JR, Kekuda R, Saha P, Prasad PD, Ganapathy V, Sundaram U. Functional characterization, localization, and molecular identification of rabbit intestinal N-amino acid transporter. American Journal of Physiology. Gastrointestinal and Liver Physiology. 294: G1301-10. PMID 18388187 DOI: 10.1152/Ajpgi.00578.2007  0.292
2005 Srinivas SR, Gopal E, Zhuang L, Itagaki S, Martin PM, Fei YJ, Ganapathy V, Prasad PD. Cloning and functional identification of slc5a12 as a sodium-coupled low-affinity transporter for monocarboxylates (SMCT2). The Biochemical Journal. 392: 655-64. PMID 16104846 DOI: 10.1042/Bj20050927  0.292
1996 Prasad PD, Huang W, Ramamoorthy S, Carter AL, Leibach FH, Ganapathy V. Sodium-dependent carnitine transport in human placental choriocarcinoma cells Biochimica Et Biophysica Acta - Biomembranes. 1284: 109-117. PMID 8865821 DOI: 10.1016/0005-2736(96)00126-5  0.292
2000 Sugawara M, Nakanishi T, Fei YJ, Huang W, Ganapathy ME, Leibach FH, Ganapathy V. Cloning of an amino acid transporter with functional characteristics and tissue expression pattern identical to that of system A. The Journal of Biological Chemistry. 275: 16473-7. PMID 10747860 DOI: 10.1074/Jbc.C000205200  0.29
2008 Karunakaran S, Umapathy NS, Thangaraju M, Hatanaka T, Itagaki S, Munn DH, Prasad PD, Ganapathy V. Interaction of tryptophan derivatives with SLC6A14 (ATB0,+) reveals the potential of the transporter as a drug target for cancer chemotherapy. The Biochemical Journal. 414: 343-55. PMID 18522536 DOI: 10.1042/Bj20080622  0.29
1999 Kekuda R, Wang H, Huang W, Pajor AM, Leibach FH, Devoe LD, Prasad PD, Ganapathy V. Primary structure and functional characteristics of a mammalian sodium-coupled high affinity dicarboxylate transporter. The Journal of Biological Chemistry. 274: 3422-9. PMID 9920886 DOI: 10.1074/Jbc.274.6.3422  0.29
2010 Ananth S, Zhuang L, Gopal E, Itagaki S, Ellappan B, Smith SB, Ganapathy V, Martin P. Diclofenac-induced stimulation of SMCT1 (SLC5A8) in a heterologous expression system: a RPE specific phenomenon. Biochemical and Biophysical Research Communications. 394: 75-80. PMID 20178774 DOI: 10.1016/J.Bbrc.2010.02.109  0.289
2001 Hatanaka T, Nakanishi T, Huang W, Leibach FH, Prasad PD, Ganapathy V, Ganapathy ME. Na+ - and Cl- -coupled active transport of nitric oxide synthase inhibitors via amino acid transport system B(0,+). The Journal of Clinical Investigation. 107: 1035-43. PMID 11306607 DOI: 10.1172/Jci12060  0.289
1999 Wang H, Dutta B, Huang W, Devoe LD, Leibach FH, Ganapathy V, Prasad PD. Human Na(+)-dependent vitamin C transporter 1 (hSVCT1): primary structure, functional characteristics and evidence for a non-functional splice variant. Biochimica Et Biophysica Acta. 1461: 1-9. PMID 10556483 DOI: 10.1016/S0005-2736(99)00182-0  0.288
2004 Fei YJ, Liu JC, Inoue K, Zhuang L, Miyake K, Miyauchi S, Ganapathy V. Relevance of NAC-2, an Na+-coupled citrate transporter, to life span, body size and fat content in Caenorhabditis elegans. The Biochemical Journal. 379: 191-8. PMID 14678010 DOI: 10.1042/Bj20031807  0.287
1994 Brandsch M, Miyamoto Y, Ganapathy V, Leibach FH. Expression and protein kinase C-dependent regulation of peptide/H+ co-transport system in the Caco-2 human colon carcinoma cell line. The Biochemical Journal. 253-60. PMID 8166648 DOI: 10.1042/bj2990253  0.287
2008 Metzner L, Natho K, Zebisch K, Dorn M, Bosse-Doenecke E, Ganapathy V, Brandsch M. Mutational analysis of histidine residues in the human proton-coupled amino acid transporter PAT1. Biochimica Et Biophysica Acta. 1778: 1042-50. PMID 18230330 DOI: 10.1016/J.Bbamem.2007.12.026  0.283
1982 Ganapathy V, Roesel RA, Leibach FH. Transport of 5-oxoproline into rabbit renal brush border membrane vesicles. Biochemical and Biophysical Research Communications. 105: 28-35. PMID 7092855 DOI: 10.1016/S0006-291X(82)80006-5  0.283
2000 Ganapathy V, Ganapathy ME, Leibach FH. Chapter 10 Intestinal transport of peptides and amino acids Current Topics in Membranes. 50: 379-412. DOI: 10.1016/S1063-5823(00)50012-X  0.283
2000 Prasad PD, Ganapathy V. Structure and function of mammalian sodium-dependent multivitamin transporter Current Opinion in Clinical Nutrition and Metabolic Care. 3: 263-266. PMID 10929671 DOI: 10.1097/00075197-200007000-00004  0.282
2000 Hatanaka T, Huang W, Wang H, Sugawara M, Prasad PD, Leibach FH, Ganapathy V. Primary structure, functional characteristics and tissue expression pattern of human ATA2, a subtype of amino acid transport system A. Biochimica Et Biophysica Acta. 1467: 1-6. PMID 10930503 DOI: 10.1016/S0005-2736(00)00252-2  0.282
1997 Kekuda R, Torres-Zamorano V, Leibach FH, Ganapathy V. Human serotonin transporter: regulation by the neuroprotective agent aurintricarboxylic acid and by epidermal growth factor. Journal of Neurochemistry. 68: 1443-50. PMID 9084414 DOI: 10.1046/J.1471-4159.1997.68041443.X  0.282
1997 Ganapathy ME, Prasad PD, Mackenzie B, Ganapathy V, Leibach FH. Interaction of anionic cephalosporins with the intestinal and renal peptide transporters PEPT 1 and PEPT 2. Biochimica Et Biophysica Acta. 1324: 296-308. PMID 9092716 DOI: 10.1016/S0005-2736(96)00234-9  0.282
1993 Leibach JW, Cool DR, Del Monte MA, Ganapathy V, Leibach FH, Miyamoto Y. Properties of taurine transport in a human retinal pigment epithelial cell line. Current Eye Research. 12: 29-36. PMID 8436008 DOI: 10.3109/02713689308999493  0.281
2000 Sugawara M, Huang W, Fei YJ, Leibach FH, Ganapathy V, Ganapathy ME. Transport of valganciclovir, a ganciclovir prodrug, via peptide transporters PEPT1 and PEPT2. Journal of Pharmaceutical Sciences. 89: 781-9. PMID 10824137 DOI: 10.1002/(Sici)1520-6017(200006)89:6<781::Aid-Jps10>3.0.Co;2-7  0.281
2017 Bhutia YD, Kopel JJ, Lawrence JJ, Neugebauer V, Ganapathy V. Plasma Membrane Na⁺-Coupled Citrate Transporter (SLC13A5) and Neonatal Epileptic Encephalopathy. Molecules (Basel, Switzerland). 22. PMID 28264506 DOI: 10.3390/Molecules22030378  0.281
2021 Higuchi K, Sivaprakasam S, Sennoune SR, Ogura J, Bhutia YD, Rueda R, Pereira SL, Ganapathy V. A Proton-Coupled Transport System for β-Hydroxy-β-Methylbutyrate (HMB) in Blood-Brain Barrier Endothelial Cell Line hCMEC/D3. Nutrients. 13. PMID 34579098 DOI: 10.3390/nu13093220  0.281
2005 Miyauchi S, Abbot EL, Zhuang L, Subramanian R, Ganapathy V, Thwaites DT. Isolation and function of the amino acid transporter PAT1 (slc36a1) from rabbit and discrimination between transport via PAT1 and system IMINO in renal brush-border membrane vesicles. Molecular Membrane Biology. 22: 549-59. PMID 16373326 DOI: 10.1080/09687860500421779  0.281
2000 Wang H, Fei YJ, Kekuda R, Yang-Feng TL, Devoe LD, Leibach FH, Prasad PD, Ganapathy V. Structure, function, and genomic organization of human Na(+)-dependent high-affinity dicarboxylate transporter. American Journal of Physiology. Cell Physiology. 278: C1019-30. PMID 10794676 DOI: 10.1152/Ajpcell.2000.278.5.C1019  0.281
1999 Prasad PD, Wang H, Huang W, Kekuda R, Rajan DP, Leibach FH, Ganapathy V. Human LAT1, a subunit of system L amino acid transporter: molecular cloning and transport function. Biochemical and Biophysical Research Communications. 255: 283-8. PMID 10049700 DOI: 10.1006/Bbrc.1999.0206  0.281
2005 Umapathy NS, Li W, Mysona BA, Smith SB, Ganapathy V. Expression and function of glutamine transporters SN1 (SNAT3) and SN2 (SNAT5) in retinal Müller cells. Investigative Ophthalmology & Visual Science. 46: 3980-7. PMID 16249471 DOI: 10.1167/Iovs.05-0488  0.279
1985 Ganapathy ME, Mahesh VB, Devoe LD, Leibach FH, Ganapathy V. Dipeptide transport in brush-border membrane vesicles isolated from normal term human placenta. American Journal of Obstetrics and Gynecology. 153: 83-6. PMID 4037005 DOI: 10.1016/0002-9378(85)90600-3  0.279
2001 Friedrich A, George RL, Bridges CC, Prasad PD, Ganapathy V. Transport of choline and its relationship to the expression of the organic cation transporters in a rat brain microvessel endothelial cell line (RBE4). Biochimica Et Biophysica Acta. 1512: 299-307. PMID 11406107 DOI: 10.1016/S0005-2736(01)00333-9  0.279
2002 Inoue K, Zhuang L, Maddox DM, Smith SB, Ganapathy V. Structure, function, and expression pattern of a novel sodium-coupled citrate transporter (NaCT) cloned from mammalian brain. The Journal of Biological Chemistry. 277: 39469-76. PMID 12177002 DOI: 10.1074/Jbc.M207072200  0.278
2010 Anderson CM, Jevons M, Thangaraju M, Edwards N, Conlon NJ, Woods S, Ganapathy V, Thwaites DT. Transport of the photodynamic therapy agent 5-aminolevulinic acid by distinct H+-coupled nutrient carriers coexpressed in the small intestine. The Journal of Pharmacology and Experimental Therapeutics. 332: 220-8. PMID 19789362 DOI: 10.1124/Jpet.109.159822  0.278
2006 Gupta N, Martin PM, Prasad PD, Ganapathy V. SLC5A8 (SMCT1)-mediated transport of butyrate forms the basis for the tumor suppressive function of the transporter. Life Sciences. 78: 2419-25. PMID 16375929 DOI: 10.1016/J.Lfs.2005.10.028  0.278
2000 Rajan PD, Kekuda R, Chancy CD, Huang W, Ganapathy V, Smith SB. Expression of the extraneuronal monoamine transporter in RPE and neural retina Current Eye Research. 20: 195-204. DOI: 10.1076/0271-3683(200003)2031-9Ft195  0.278
2001 Gazzola RF, Sala R, Bussolati O, Visigalli R, Dall'Asta V, Ganapathy V, Gazzola GC. The adaptive regulation of amino acid transport system A is associated to changes in ATA2 expression. Febs Letters. 490: 11-4. PMID 11172802 DOI: 10.1016/S0014-5793(01)02126-3  0.278
1997 Torres-Zamorano V, Leibach FH, Ganapathy V. Regulation of transport function in choriocarcinoma cells by GM1 ganglioside Faseb Journal. 11.  0.278
1989 Kulanthaivel P, Leibach FH, Mahesh VB, Ganapathy V. Tyrosine residues are essential for the activity of the human placental taurine transporter. Biochimica Et Biophysica Acta. 985: 139-46. PMID 2804101 DOI: 10.1016/0005-2736(89)90358-1  0.277
2010 Chothe PP, Thakkar SV, Gnana-Prakasam JP, Ananth S, Hinton DR, Kannan R, Smith SB, Martin PM, Ganapathy V. Identification of a novel sodium-coupled oligopeptide transporter (SOPT2) in mouse and human retinal pigment epithelial cells. Investigative Ophthalmology & Visual Science. 51: 413-20. PMID 19643969 DOI: 10.1167/Iovs.09-4048  0.276
2007 Umapathy NS, Gnana-Prakasam JP, Martin PM, Mysona B, Dun Y, Smith SB, Ganapathy V, Prasad PD. Cloning and functional characterization of the proton-coupled electrogenic folate transporter and analysis of its expression in retinal cell types. Investigative Ophthalmology & Visual Science. 48: 5299-305. PMID 17962486 DOI: 10.1167/Iovs.07-0288  0.276
2008 Thangaraju M, Cresci G, Itagaki S, Mellinger J, Browning DD, Berger FG, Prasad PD, Ganapathy V. Sodium-coupled transport of the short chain fatty acid butyrate by SLC5A8 and its relevance to colon cancer. Journal of Gastrointestinal Surgery : Official Journal of the Society For Surgery of the Alimentary Tract. 12: 1773-81; discussion . PMID 18661192 DOI: 10.1007/S11605-008-0573-0  0.276
2004 Anderson CM, Grenade DS, Boll M, Foltz M, Wake KA, Kennedy DJ, Munck LK, Miyauchi S, Taylor PM, Campbell FC, Munck BG, Daniel H, Ganapathy V, Thwaites DT. H+/amino acid transporter 1 (PAT1) is the imino acid carrier: An intestinal nutrient/drug transporter in human and rat. Gastroenterology. 127: 1410-22. PMID 15521011 DOI: 10.1053/J.Gastro.2004.08.017  0.275
1998 Prasad PD, Huang W, Wang H, Leibach FH, Ganapathy V. Transport mechanisms for vitamin C in the JAR human placental choriocarcinoma cell line. Biochimica Et Biophysica Acta. 1369: 141-51. PMID 9528682 DOI: 10.1016/S1071-5576(97)86428-3  0.274
2004 Jain-Vakkalagadda B, Pal D, Gunda S, Nashed Y, Ganapathy V, Mitra AK. Identification of a Na+-dependent cationic and neutral amino acid transporter, B(0,+), in human and rabbit cornea. Molecular Pharmaceutics. 1: 338-46. PMID 16026003 DOI: 10.1021/Mp0499499  0.273
2002 Kennedy DJ, Leibach FH, Ganapathy V, Thwaites DT. Optimal absorptive transport of the dipeptide glycylsarcosine is dependent on functional Na+/H+ exchange activity. PflüGers Archiv : European Journal of Physiology. 445: 139-46. PMID 12397398 DOI: 10.1007/S00424-002-0910-1  0.273
1993 Ramamoorthy S, Kulanthaivel P, Leibach FH, Mahesh VB, Ganapathy V. Solubilization and functional reconstitution of the human placental taurine transporter. Biochimica Et Biophysica Acta. 1145: 250-6. PMID 8431457 DOI: 10.1016/0005-2736(93)90296-C  0.273
2006 Ganapathy V, Fei YJ, Prasad PD. Heterologous expression systems for studying placental transporters. Methods in Molecular Medicine. 122: 285-300. PMID 16511988 DOI: 10.1385/1-59259-989-3:285  0.273
1996 Leibach FH, Ganapathy V. Peptide transporters in the intestine and the kidney Annual Review of Nutrition. 16: 99-119. PMID 8839921 DOI: 10.1146/Annurev.Nu.16.070196.000531  0.273
1981 Ganapathy V, Mendicino J, Leibach FH. Evidence for a dipeptide transport system in renal brush border membranes from rabbit. Biochimica Et Biophysica Acta. 642: 381-91. PMID 7284363 DOI: 10.1016/0005-2736(81)90454-5  0.273
1995 Ramamoorthy JD, Ramamoorthy S, Papapetropoulos A, Catravas JD, Leibach FH, Ganapathy V. Cyclic AMP-independent up-regulation of the human serotonin transporter by staurosporine in choriocarcinoma cells Journal of Biological Chemistry. 270: 17189-17195. PMID 7615516 DOI: 10.1074/Jbc.270.29.17189  0.272
2001 Avissar NE, Ziegler TR, Wang HT, Gu LH, Miller JH, Iannoli P, Leibach FH, Ganapathy V, Sax HC. Growth factors regulation of rabbit sodium-dependent neutral amino acid transporter ATB0 and oligopeptide transporter 1 mRNAs expression after enteretomy. Jpen. Journal of Parenteral and Enteral Nutrition. 25: 65-72. PMID 11284472 DOI: 10.1177/014860710102500265  0.272
2004 Miyauchi S, Gopal E, Fei YJ, Ganapathy V. Functional identification of SLC5A8, a tumor suppressor down-regulated in colon cancer, as a Na(+)-coupled transporter for short-chain fatty acids. The Journal of Biological Chemistry. 279: 13293-6. PMID 14966140 DOI: 10.1074/Jbc.C400059200  0.272
1998 Ganapathy V, Prasad PD, Leibach FH. Use of human placenta in studies of monoamine transporters. Methods in Enzymology. 296: 278-90. PMID 9779455 DOI: 10.1016/S0076-6879(98)96021-9  0.271
1994 Ramamoorthy S, Leibach FH, Mahesh VB, Han H, Yang-Feng T, Blakely RD, Ganapathy V. Functional characterization and chromosomal localization of a cloned taurine transporter from human placenta. The Biochemical Journal. 300: 893-900. PMID 8010975 DOI: 10.1042/Bj3000893  0.269
1995 Ramamoorthy JD, Ramamoorthy S, Leibach FH, Ganapathy V. Human placental monoamine transporters as targets for amphetamines American Journal of Obstetrics and Gynecology. 173: 1782-1787. PMID 8610762 DOI: 10.1016/0002-9378(95)90427-1  0.268
1998 Fei YJ, Fujita T, Lapp DF, Ganapathy V, Leibach FH. Two oligopeptide transporters from Caenorhabditis elegans: molecular cloning and functional expression. The Biochemical Journal. 565-72. PMID 9601088 DOI: 10.1042/Bj3320565  0.268
2008 Anderson CM, Ganapathy V, Thwaites DT. Human solute carrier SLC6A14 is the beta-alanine carrier. The Journal of Physiology. 586: 4061-7. PMID 18599538 DOI: 10.1113/Jphysiol.2008.154500  0.267
2016 Bhutia YD, Babu E, Ramachandran S, Yang S, Thangaraju M, Ganapathy V. SLC transporters as a novel class of tumour suppressors: identity, function and molecular mechanisms. The Biochemical Journal. 473: 1113-24. PMID 27118869 DOI: 10.1042/Bj20150751  0.267
2000 Prasad PD, Srinivas SR, Wang H, Leibach FH, Devoe LD, Ganapathy V. Electrogenic nature of rat sodium-dependent multivitamin transport. Biochemical and Biophysical Research Communications. 270: 836-40. PMID 10772912 DOI: 10.1006/Bbrc.2000.2498  0.267
1988 Tiruppathi C, Miyamoto Y, Ganapathy V, Leibach FH. Fatty acid-induced alterations in transport systems of the small intestinal brush-border membrane. Biochemical Pharmacology. 37: 1399-405. PMID 2833280 DOI: 10.1016/0006-2952(88)90800-3  0.267
2015 Bhutia YD, Babu E, Ramachandran S, Ganapathy V. Amino Acid transporters in cancer and their relevance to "glutamine addiction": novel targets for the design of a new class of anticancer drugs. Cancer Research. 75: 1782-8. PMID 25855379 DOI: 10.1158/0008-5472.Can-14-3745  0.267
2000 Chancy CD, Kekuda R, Huang W, Prasad PD, Kuhnel JM, Sirotnak FM, Roon P, Ganapathy V, Smith SB. Expression and differential polarization of the reduced-folate transporter-1 and the folate receptor alpha in mammalian retinal pigment epithelium. The Journal of Biological Chemistry. 275: 20676-84. PMID 10787414 DOI: 10.1074/jbc.M002328200  0.266
2006 Gupta N, Prasad PD, Ghamande S, Moore-Martin P, Herdman AV, Martindale RG, Podolsky R, Mager S, Ganapathy ME, Ganapathy V. Up-regulation of the amino acid transporter ATB(0,+) (SLC6A14) in carcinoma of the cervix. Gynecologic Oncology. 100: 8-13. PMID 16168467 DOI: 10.1016/J.Ygyno.2005.08.016  0.266
2001 Hatanaka T, Huang W, Ling R, Prasad PD, Sugawara M, Leibach FH, Ganapathy V. Evidence for the transport of neutral as well as cationic amino acids by ATA3, a novel and liver-specific subtype of amino acid transport system A. Biochimica Et Biophysica Acta. 1510: 10-7. PMID 11342143 DOI: 10.1016/S0005-2736(00)00390-4  0.265
1995 Ganapathy ME, Brandsch M, Prasad PD, Ganapathy V, Leibach FH. Differential recognition of beta -lactam antibiotics by intestinal and renal peptide transporters, PEPT 1 and PEPT 2. The Journal of Biological Chemistry. 270: 25672-7. PMID 7592745 DOI: 10.1074/Jbc.270.43.25672  0.265
1988 Miyamoto Y, Balkovetz DF, Leibach FH, Mahesh VB, Ganapathy V. Na+ + Cl- -gradient-driven, high-affinity, uphill transport of taurine in human placental brush-border membrane vesicles. Febs Letters. 231: 263-7. PMID 3360130 DOI: 10.1016/0014-5793(88)80744-0  0.265
2006 Yodoya E, Wada M, Shimada A, Katsukawa H, Okada N, Yamamoto A, Ganapathy V, Fujita T. Functional and molecular identification of sodium-coupled dicarboxylate transporters in rat primary cultured cerebrocortical astrocytes and neurons. Journal of Neurochemistry. 97: 162-73. PMID 16524379 DOI: 10.1111/J.1471-4159.2006.03720.X  0.265
2009 Gopal E, Fei YJ, Miyauchi S, Zhuang L, Prasad PD, Ganapathy V. Sodium-coupled and electrogenic transport of B-complex vitamin nicotinic acid by slc5a8, a member of the Na/glucose co-transporter gene family. The Biochemical Journal. 388: 309-16. PMID 15651982 DOI: 10.1042/Bj20041916  0.264
1999 Fujita T, Majikawa Y, Umehisa S, Okada N, Yamamoto A, Ganapathy V, Leibach FH. sigma Receptor ligand-induced up-regulation of the H(+)/peptide transporter PEPT1 in the human intestinal cell line Caco-2. Biochemical and Biophysical Research Communications. 261: 242-6. PMID 10425172 DOI: 10.1006/Bbrc.1999.1026  0.264
1993 Ramamoorthy S, Leibach FH, Mahesh VB, Ganapathy V. Partial purification and characterization of the human placental serotonin transporter. Placenta. 14: 449-61. PMID 8248037 DOI: 10.1016/S0143-4004(05)80465-5  0.264
2014 Bhutia YD, Babu E, Prasad PD, Ganapathy V. The amino acid transporter SLC6A14 in cancer and its potential use in chemotherapy Asian Journal of Pharmaceutical Sciences. 9: 293-303. DOI: 10.1016/J.Ajps.2014.04.004  0.264
2001 Sugawara M, Nakanishi T, Fei YJ, Martindale RG, Ganapathy ME, Leibach FH, Ganapathy V. Structure and function of ATA3, a new subtype of amino acid transport system A, primarily expressed in the liver and skeletal muscle. Biochimica Et Biophysica Acta. 1509: 7-13. PMID 11118514 DOI: 10.1016/S0005-2736(00)00349-7  0.263
2007 Gopal E, Miyauchi S, Martin PM, Ananth S, Roon P, Smith SB, Ganapathy V. Transport of nicotinate and structurally related compounds by human SMCT1 (SLC5A8) and its relevance to drug transport in the mammalian intestinal tract. Pharmaceutical Research. 24: 575-84. PMID 17245649 DOI: 10.1007/S11095-006-9176-1  0.263
2015 Gopal E, Babu E, Ramachandran S, Bhutia YD, Prasad PD, Ganapathy V. Species-specific influence of lithium on the activity of SLC13A5 (NaCT): lithium-induced activation is specific for the transporter in primates. The Journal of Pharmacology and Experimental Therapeutics. 353: 17-26. PMID 25617245 DOI: 10.1124/Jpet.114.221523  0.262
1995 Prasad PD, Ramamoorthy S, Leibach FH, Ganapathy V. Molecular Cloning of the Human Placental Folate Transporter Biochemical and Biophysical Research Communications. 206: 681-687. PMID 7826387 DOI: 10.1006/Bbrc.1995.1096  0.262
1989 Miyamoto Y, Tiruppathi C, Ganapathy V, Leibach FH. Active transport of taurine in rabbit jejunal brush-border membrane vesicles. The American Journal of Physiology. 257: G65-72. PMID 2750911 DOI: 10.1152/ajpgi.1989.257.1.G65  0.262
1995 Ramamoorthy S, Ramamoorthy JD, Prasad PD, Bhat GK, Mahesh VB, Leibach FH, Ganapathy V. Regulation of the human serotonin transporter by interleukin-1 beta. Biochemical and Biophysical Research Communications. 216: 560-7. PMID 7488148 DOI: 10.1006/Bbrc.1995.2659  0.262
1982 Ganapathy V, Mendicino JF, Leibach FH. Effect of papain treatment on dipeptide transport into rabbit intestinal brush border vesicles. Life Sciences. 29: 2451-7. PMID 7321770 DOI: 10.1016/0024-3205(81)90699-8  0.261
2004 El-Sherbeny A, Naggar H, Miyauchi S, Ola MS, Maddox DM, Martin PM, Ganapathy V, Smith SB. Osmoregulation of taurine transporter function and expression in retinal pigment epithelial, ganglion, and müller cells. Investigative Ophthalmology & Visual Science. 45: 694-701. PMID 14744916 DOI: 10.1167/Iovs.03-0503  0.261
1993 Ganapathy V, Ramamoorthy S, Leibach FH. Transport and metabolism of monoamines in the human placenta Placenta. 14: 35-51. DOI: 10.1016/S0143-4004(05)80281-4  0.261
1992 Tiruppathi C, Brandsch M, Miyamoto Y, Ganapathy V, Leibach FH. Constitutive expression of the taurine transporter in a human colon carcinoma cell line. The American Journal of Physiology. 263: G625-31. PMID 1443137 DOI: 10.1152/Ajpgi.1992.263.5.G625  0.261
2003 Prasad PD, Ganapathy V. Keratinocytes join forces with immune cells in the prosecution of SMVT as a "False" biotin transporter Journal of Investigative Dermatology. 120. PMID 12603871 DOI: 10.1046/J.1523-1747.2003.12075.X  0.261
2003 Friedrich A, Prasad PD, Freyer D, Ganapathy V, Brust P. Molecular cloning and functional characterization of the OCTN2 transporter at the RBE4 cells, an in vitro model of the blood-brain barrier Brain Research. 968: 69-79. PMID 12644265 DOI: 10.1016/S0006-8993(02)04271-3  0.261
1982 Ganapathy V, Leibach FH. Transport and utilization of methionine sulfoxide in the rabbit Bba - Biomembranes. 693: 305-314. PMID 7159581 DOI: 10.1016/0005-2736(82)90436-9  0.261
1994 Fei YJ, Kanai Y, Nussberger S, Ganapathy V, Leibach FH, Romero MF, Singh SK, Boron WF, Hediger MA. Expression cloning of a mammalian proton-coupled oligopeptide transporter Nature. 368: 563-566. PMID 8139693 DOI: 10.1038/368563A0  0.26
1997 Fei YJ, Liu W, Prasad PD, Kekuda R, Oblak TG, Ganapathy V, Leibach FH. Identification of the histidyl residue obligatory for the catalytic activity of the human H+/peptide cotransporters PEPT1 and PEPT2. Biochemistry. 36: 452-60. PMID 9003198 DOI: 10.1021/Bi962058P  0.26
1997 Fei YJ, Ganapathy V, Leibach FH. Molecular and structural features of the proton-coupled oligopeptide transporter superfamily. Progress in Nucleic Acid Research and Molecular Biology. 58: 239-61. PMID 9308368 DOI: 10.1016/S0079-6603(08)60038-0  0.26
1999 Huang W, Shaikh SN, Ganapathy ME, Hopfer U, Leibach FH, Carter AL, Ganapathy V. Carnitine transport and its inhibition by sulfonylureas in human kidney proximal tubular epithelial cells Biochemical Pharmacology. 58: 1361-1370. PMID 10487540 DOI: 10.1016/S0006-2952(99)00219-1  0.259
2021 Schniers B, Rajasekaran D, Korac K, Sniegowski T, Ganapathy V, Bhutia YD. PEPT1 is essential for the growth of pancreatic cancer cells: A viable drug target. The Biochemical Journal. PMID 34569600 DOI: 10.1042/BCJ20210377  0.259
2008 Kozlowski DJ, Chen Z, Zhuang L, Fei YJ, Navarre S, Ganapathy V. Molecular characterization and expression pattern of taurine transporter in zebrafish during embryogenesis. Life Sciences. 82: 1004-11. PMID 18407297 DOI: 10.1016/J.Lfs.2008.02.015  0.258
2001 Nakanishi T, Sugawara M, Huang W, Martindale RG, Leibach FH, Ganapathy ME, Prasad PD, Ganapathy V. Structure, function, and tissue expression pattern of human SN2, a subtype of the amino acid transport system N. Biochemical and Biophysical Research Communications. 281: 1343-8. PMID 11243884 DOI: 10.1006/Bbrc.2001.4504  0.258
1996 Kekuda R, Prasad PD, Fei YJ, Torres-Zamorano V, Sinha S, Yang-Feng TL, Leibach FH, Ganapathy V. Cloning of the sodium-dependent, broad-scope, neutral amino acid transporter Bo from a human placental choriocarcinoma cell line. The Journal of Biological Chemistry. 271: 18657-61. PMID 8702519 DOI: 10.1074/Jbc.271.31.18657  0.257
2007 Martin PM, Dun Y, Mysona B, Ananth S, Roon P, Smith SB, Ganapathy V. Expression of the sodium-coupled monocarboxylate transporters SMCT1 (SLC5A8) and SMCT2 (SLC5A12) in retina. Investigative Ophthalmology & Visual Science. 48: 3356-63. PMID 17591909 DOI: 10.1167/Iovs.06-0888  0.257
2005 Ganapathy V, Gopal E, Miyauchi S, Prasad PD. Biological functions of SLC5A8, a candidate tumour suppressor. Biochemical Society Transactions. 33: 237-40. PMID 15667316 DOI: 10.1042/BST0330237  0.256
2015 Bhutia YD, Babu E, Singh PK, Ganapathy V. Abstract 348: Amino acid-based prodrugs of gemcitabine - a therapeutic option to overcome chemoresistance in pancreatic cancer Cancer Research. 75: 348-348. DOI: 10.1158/1538-7445.Am2015-348  0.256
1986 Miyamoto Y, Ganapathy V, Leibach FH. Identification of histidyl and thiol groups at the active site of rabbit renal dipeptide transporter Journal of Biological Chemistry. 261: 16133-16140. PMID 3023343  0.256
2005 Kennedy DJ, Gatfield KM, Winpenny JP, Ganapathy V, Thwaites DT. Substrate specificity and functional characterisation of the H+/amino acid transporter rat PAT2 (Slc36a2). British Journal of Pharmacology. 144: 28-41. PMID 15644866 DOI: 10.1038/Sj.Bjp.0706029  0.255
1999 Wang H, Huang W, Fei YJ, Xia H, Yang-Feng TL, Leibach FH, Devoe LD, Ganapathy V, Prasad PD. Human placental Na+-dependent multivitamin transporter. Cloning, functional expression, gene structure, and chromosomal localization. The Journal of Biological Chemistry. 274: 14875-83. PMID 10329687 DOI: 10.1074/jbc.274.21.14875  0.255
1988 Ganapathy V, Ganapathy ME, Tiruppathi C, Miyamoto Y, Mahesh VB, Leibach FH. Sodium-gradient-driven, high-affinity, uphill transport of succinate in human placental brush-border membrane vesicles. The Biochemical Journal. 249: 179-84. PMID 3342005 DOI: 10.1042/bj2490179  0.255
2000 Rajan DP, Kekuda R, Huang W, Devoe LD, Leibach FH, Prasad PD, Ganapathy V. Cloning and functional characterization of a Na(+)-independent, broad-specific neutral amino acid transporter from mammalian intestine. Biochimica Et Biophysica Acta. 1463: 6-14. PMID 10631289 DOI: 10.1016/S0005-2736(99)00224-2  0.255
2013 Coothankandaswamy V, Elangovan S, Singh N, Prasad PD, Thangaraju M, Ganapathy V. The plasma membrane transporter SLC5A8 suppresses tumour progression through depletion of survivin without involving its transport function. The Biochemical Journal. 450: 169-78. PMID 23167260 DOI: 10.1042/Bj20121248  0.255
2021 Kopel JJ, Bhutia YD, Sivaprakasam S, Ganapathy V. Consequences of NaCT/SLC13A5/mINDY deficiency: good versus evil, separated only by the blood-brain barrier. The Biochemical Journal. 478: 463-486. PMID 33544126 DOI: 10.1042/BCJ20200877  0.255
2020 Higuchi K, Sato T, Bhutia YD, Ganapathy V. Involvement of a Na-coupled Oligopeptide Transport System for β-amyloid Peptide (Aβ) in Brain Cells. Pharmaceutical Research. 37: 98. PMID 32419062 DOI: 10.1007/S11095-020-02835-7  0.255
2020 Jaramillo-Martinez V, Urbatsch IL, Ganapathy V. Expression of Functional Human Na+- Coupled Citrate Transporter (SLC13A5) in the Yeast Pichia pastoris Biophysical Journal. 118. DOI: 10.1016/J.Bpj.2019.11.1250  0.255
2021 Jaramillo-Martinez V, Sivaprakasam S, Ganapathy V, Urbatsch IL. INDY and Mammalian INDY: Major Differences in Transport Mechanism and Structural Features despite Mostly Similar Biological Functions. Metabolites. 11. PMID 34677384 DOI: 10.3390/metabo11100669  0.254
2001 Ling R, Bridges CC, Sugawara M, Fujita T, Leibach FH, Prasad PD, Ganapathy V. Involvement of transporter recruitment as well as gene expression in the substrate-induced adaptive regulation of amino acid transport system A Biochimica Et Biophysica Acta - Biomembranes. 1512: 15-21. PMID 11334620 DOI: 10.1016/S0005-2736(01)00310-8  0.254
2002 Fei YJ, Inoue K, Ganapathy V. Structural and functional characteristics of two sodium-coupled dicarboxylate transporters (ceNaDC1 and ceNaDC2) from Caenorhabditis elegans and their relevance to life span. The Journal of Biological Chemistry. 278: 6136-44. PMID 12480943 DOI: 10.1074/Jbc.M208763200  0.254
2009 Ganapathy V. A traffic signal for heterodimeric amino acid transporters to transfer from the ER to the Golgi. The Biochemical Journal. 417: e9-11. PMID 19099537 DOI: 10.1042/Bj20082246  0.254
2007 Dun Y, Mysona B, Itagaki S, Martin-Studdard A, Ganapathy V, Smith SB. Functional and molecular analysis of D-serine transport in retinal Müller cells. Experimental Eye Research. 84: 191-9. PMID 17094966 DOI: 10.1016/J.Exer.2006.09.015  0.253
2005 Alteheld B, Evans ME, Gu LH, Ganapathy V, Leibach FH, Jones DP, Ziegler TR. Alanylglutamine dipeptide and growth hormone maintain PepT1-mediated transport in oxidatively stressed Caco-2 cells. The Journal of Nutrition. 135: 19-26. PMID 15623827 DOI: 10.1093/Jn/135.1.19  0.253
2011 Babu E, Thangaraju M, Ganapathy V. Abstract 2198: Role of SLC5A8, a plasma membrane transporter and a tumor suppressor, in the antitumor activity of dichloroacetate Cancer Research. 71: 2198-2198. DOI: 10.1158/1538-7445.Am2011-2198  0.253
2001 Avissar NE, Ryan CK, Ganapathy V, Sax HC. Na(+)-dependent neutral amino acid transporter ATB(0) is a rabbit epithelial cell brush-border protein. American Journal of Physiology. Cell Physiology. 281: C963-71. PMID 11502573 DOI: 10.1152/Ajpcell.2001.281.3.C963  0.252
1998 Wu X, Prasad PD, Leibach FH, Ganapathy V. cDNA sequence, transport function, and genomic organization of human OCTN2, a new member of the organic cation transporter family. Biochemical and Biophysical Research Communications. 246: 589-95. PMID 9618255 DOI: 10.1006/Bbrc.1998.8669  0.252
2013 Chothe PP, Chutkan N, Sangani R, Wenger KH, Prasad PD, Thangaraju M, Hamrick MW, Isales CM, Ganapathy V, Fulzele S. Sodium-coupled vitamin C transporter (SVCT2): expression, function, and regulation in intervertebral disc cells. The Spine Journal : Official Journal of the North American Spine Society. 13: 549-57. PMID 23415019 DOI: 10.1016/J.Spinee.2013.01.022  0.252
2007 Miyauchi S, Gopal E, Thakkar SV, Ichikawa S, Prasad PD, Ganapathy V. Differential modulation of sodium- and chloride-dependent opioid peptide transport system by small nonopioid peptides and free amino acids Journal of Pharmacology and Experimental Therapeutics. 321: 257-264. PMID 17259448 DOI: 10.1124/Jpet.106.116806  0.251
2003 Inoue K, Zhuang L, Maddox DM, Smith SB, Ganapathy V. Human sodium-coupled citrate transporter, the orthologue of Drosophila Indy, as a novel target for lithium action. The Biochemical Journal. 374: 21-6. PMID 12826022 DOI: 10.1042/Bj20030827  0.251
1991 Cool D, Leibach F, Bhalla V, Mahesh V, Ganapathy V. Expression and cyclic AMP-dependent regulation of a high affinity serotonin transporter in the human placental choriocarcinoma cell line (JAR) Journal of Biological Chemistry. 266: 15750-15757. DOI: 10.1016/s0021-9258(18)98473-5  0.251
1998 PRASAD P, WANG H, KEKUDA R, FUJITA T, FEI Y, DEVOE L, LEIBACH F, GANAPATHY V. Cloning and functional expression of a cDNA encoding a mammalian sodium-dependent vitamin transporter mediating the uptake of pantothenate, biotin, and lipoate Journal of the Society For Gynecologic Investigation. 5: 124A-124A. DOI: 10.1016/S1071-5576(97)86427-1  0.25
1988 Barfuss DW, Ganapathy V, Leibach FH. Evidence for active dipeptide transport in isolated proximal straight tubules American Journal of Physiology - Renal Fluid and Electrolyte Physiology. 255. PMID 3293467 DOI: 10.1152/ajprenal.1988.255.1.F177  0.25
2020 Jaramillo-Martinez V, Urbatsch IL, Ganapathy V. Functional Distinction between Human and Mouse Sodium-Coupled Citrate Transporters and Its Biologic Significance: An Attempt for Structural Basis Using a Homology Modeling Approach. Chemical Reviews. PMID 33040525 DOI: 10.1021/acs.chemrev.0c00529  0.25
2002 Hatanaka T, Huang W, Nakanishi T, Bridges CC, Smith SB, Prasad PD, Ganapathy ME, Ganapathy V. Transport of D-serine via the amino acid transporter ATB(0,+) expressed in the colon. Biochemical and Biophysical Research Communications. 291: 291-5. PMID 11846403 DOI: 10.1006/Bbrc.2002.6441  0.25
1989 Miyamoto Y, Tiruppathi C, Ganapathy V, Leibach FH. Involvement of thiol groups in the function of the dipeptide/proton cotransport system in rabbit renal brush-border membrane vesicles. Biochimica Et Biophysica Acta. 978: 25-31. PMID 2536554 DOI: 10.1016/0005-2736(89)90493-8  0.249
2020 Higuchi K, Kopel JJ, Sivaprakasam S, Jaramillo-Martinez V, Sutton RB, Urbatsch IL, Ganapathy V. Functional analysis of a species-specific inhibitor selective for human Na+-coupled citrate transporter (NaCT/SLC13A5/mINDY). The Biochemical Journal. PMID 33079129 DOI: 10.1042/BCJ20200592  0.249
1997 Prasad PD, Torres-Zamorano V, Kekuda R, Leibach FH, Ganapathy V. Functional link between tyrosine phosphorylation and human serotonin transporter gene expression. European Journal of Pharmacology. 325: 85-92. PMID 9151943 DOI: 10.1016/S0014-2999(97)00100-3  0.249
2012 Bozard BR, Chothe PP, Tawfik A, Williams C, Fulzele S, Prasad PD, Martin PM, Ganapathy V, Smith SB. Regulation of proton-coupled folate transporter in retinal Müller cells by the antipsoriatic drug monomethylfumarate. Glia. 60: 333-42. PMID 22072423 DOI: 10.1002/Glia.22266  0.249
2002 Inoue K, Fei YJ, Huang W, Zhuang L, Chen Z, Ganapathy V. Functional identity of Drosophila melanogaster Indy as a cation-independent, electroneutral transporter for tricarboxylic acid-cycle intermediates. The Biochemical Journal. 367: 313-9. PMID 12186628 DOI: 10.1042/Bj20021132  0.249
2004 Ganapathy V, Smith SB, Prasad PD. SLC19: the folate/thiamine transporter family. Pflã¼Gers Archiv : European Journal of Physiology. 447: 641-6. PMID 14770311 DOI: 10.1007/S00424-003-1068-1  0.249
1986 Ganapathy ME, Leibach FH, Mahesh VB, Howard JC, Devoe LD, Ganapathy V. Characterization of tryptophan transport in human placental brush-border membrane vesicles. The Biochemical Journal. 238: 201-8. PMID 3800932  0.249
2000 Wu X, Huang W, Ganapathy ME, Wang H, Kekuda R, Conway SJ, Leibach FH, Ganapathy V. Structure, function, and regional distribution of the organic cation transporter OCT3 in the kidney. American Journal of Physiology. Renal Physiology. 279: F449-58. PMID 10966924 DOI: 10.1152/Ajprenal.2000.279.3.F449  0.248
1997 Kekuda R, Torres-Zamorano V, Fei YJ, Prasad PD, Li HW, Mader LD, Leibach FH, Ganapathy V. Molecular and functional characterization of intestinal Na(+)-dependent neutral amino acid transporter B0. The American Journal of Physiology. 272: G1463-72. PMID 9227483 DOI: 10.1152/Ajpgi.1997.272.6.G1463  0.248
2020 Ananth S, Miyauchi S, Thangaraju M, Jadeja RN, Bartoli M, Ganapathy V, Martin PM. Selenomethionine (Se-Met) Induces the Cystine/Glutamate Exchanger SLC7A11 in Cultured Human Retinal Pigment Epithelial (RPE) Cells: Implications for Antioxidant Therapy in Aging Retina. Antioxidants (Basel, Switzerland). 10. PMID 33374239 DOI: 10.3390/antiox10010009  0.248
2010 Becker HM, Mohebbi N, Perna A, Ganapathy V, Capasso G, Wagner CA. Localization of members of MCT monocarboxylate transporter family Slc16 in the kidney and regulation during metabolic acidosis. American Journal of Physiology. Renal Physiology. 299: F141-54. PMID 20392797 DOI: 10.1152/Ajprenal.00488.2009  0.246
1999 Wu X, Kekuda R, Huang W, Fei YJ, Leibach FH, Chen J, Conway SJ, Ganapathy V. Identity of the organic cation transporter OCT3 as the extraneuronal monoamine transporter (uptake2) and evidence for the expression of the transporter in the brain. The Journal of Biological Chemistry. 273: 32776-86. PMID 9830022 DOI: 10.1074/Jbc.273.49.32776  0.246
1989 Tiruppathi C, Balkovetz DF, Ganapathy V, Miyamoto Y, Leibach FH. A proton gradient, not a sodium gradient, is the driving force for active transport of lactate in rabbit intestinal brush-border membrane vesicles. The Biochemical Journal. 256: 219-23. PMID 2851979 DOI: 10.1042/bj2560219  0.245
2020 Ristic B, Sikder MOF, Bhutia YD, Ganapathy V. Pharmacologic inducers of the uric acid exporter ABCG2 as potential drugs for treatment of gouty arthritis. Asian Journal of Pharmaceutical Sciences. 15: 173-180. PMID 32373197 DOI: 10.1016/J.Ajps.2019.10.002  0.244
1991 Ganapathy V, Leibach FH. Proton-coupled solute transport in the animal cell plasma membrane Current Opinion in Cell Biology. 3: 695-701. PMID 1663375 DOI: 10.1016/0955-0674(91)90043-X  0.244
2012 Coothan-Kandaswamy V, Elangovan S, Thangaraju M, Ganapathy V. Abstract 1310: SLC5A8 functions as a tumor suppressor through redistribution and depletion of survivin Cancer Research. 72: 1310-1310. DOI: 10.1158/1538-7445.Am2012-1310  0.244
2014 Ellappan B, Bhutia YD, Thangaraju M, Prasad PD, Ganapathy V. Abstract 3928: Genetic deletion or pharmacologic blockade of the amino acid transporter Slc6a14 in mice suppresses breast cancer induced by Polyoma middle T oncogene Cancer Research. 74: 3928-3928. DOI: 10.1158/1538-7445.Am2014-3928  0.244
2008 Umapathy NS, Dun Y, Martin PM, Duplantier JN, Roon P, Prasad P, Smith SB, Ganapathy V. Expression and function of system N glutamine transporters (SN1/SN2 or SNAT3/SNAT5) in retinal ganglion cells. Investigative Ophthalmology & Visual Science. 49: 5151-60. PMID 18689705 DOI: 10.1167/Iovs.08-2245  0.244
1990 Cool DR, Liebach FH, Ganapathy V. Interaction of fluoxetine with the human placental serotonin transporter Biochemical Pharmacology. 40: 2161-2167. PMID 2146964 DOI: 10.1016/0006-2952(90)90249-K  0.244
2005 Gaildrat P, Møller M, Mukda S, Humphries A, Carter DA, Ganapathy V, Klein DC. A novel pineal-specific product of the oligopeptide transporter PepT1 gene: circadian expression mediated by cAMP activation of an intronic promoter. The Journal of Biological Chemistry. 280: 16851-60. PMID 15684415 DOI: 10.1074/Jbc.M414587200  0.244
2005 Fujita T, Katsukawa H, Yodoya E, Wada M, Shimada A, Okada N, Yamamoto A, Ganapathy V. Transport characteristics of N-acetyl-L-aspartate in rat astrocytes: involvement of sodium-coupled high-affinity carboxylate transporter NaC3/NaDC3-mediated transport system. Journal of Neurochemistry. 93: 706-14. PMID 15836629 DOI: 10.1111/J.1471-4159.2005.03067.X  0.244
1998 Börner V, Fei YJ, Hartrodt B, Ganapathy V, Leibach FH, Neubert K, Brandsch M. Transport of amino acid aryl amides by the intestinal H+/peptide cotransport system, PEPT1. European Journal of Biochemistry. 255: 698-702. PMID 9738910 DOI: 10.1046/J.1432-1327.1998.2550698.X  0.244
2007 Miyauchi S, Seki A, Kikukawa T, Aoyama K, Demura M, Ganapathy V, Kamo N. 2P302 Mechanism of proton transport via azide-bound halorhodopsin from Natronomonas pharaonis(Native and artificial biomembranes-transport,Poster Presentations) Seibutsu Butsuri. 47: S188. DOI: 10.2142/Biophys.47.S188_3  0.243
1995 Brandsch M, Ramamoorthy S, Marczin N, Catravas JD, Leibach JW, Ganapathy V, Leibach FH. Regulation of taurine transport by Escherichia coli heat-stable enterotoxin and guanylin in human intestinal cell lines. The Journal of Clinical Investigation. 96: 361-9. PMID 7615806 DOI: 10.1172/Jci118042  0.243
1998 Ganapathy ME, Huang W, Wang H, Ganapathy V, Leibach FH. Valacyclovir: a substrate for the intestinal and renal peptide transporters PEPT1 and PEPT2. Biochemical and Biophysical Research Communications. 246: 470-5. PMID 9610386 DOI: 10.1006/Bbrc.1998.8628  0.243
1993 Brandsch M, Miyamoto Y, Ganapathy V, Leibach FH. Regulation of taurine transport in human colon carcinoma cell lines (HT-29 and Caco-2) by protein kinase C. The American Journal of Physiology. 264: G939-46. PMID 8498520 DOI: 10.1152/Ajpgi.1993.264.5.G939  0.243
1992 Ramamoorthy S, Leibach FH, Mahesh VB, Ganapathy V. Selective impairment of taurine transport by cyclosporin A in a human placental cell line. Pediatric Research. 32: 125-7. PMID 1378960 DOI: 10.1203/00006450-199207000-00024  0.243
1993 Ramamoorthy S, Prasad PD, Kulanthaivel P, Leibach FH, Blakely RD, Ganapathy V. Expression of a cocaine-sensitive norepinephrine transporter in the human placental syncytiotrophoblast. Biochemistry. 32: 1346-53. PMID 8448143 DOI: 10.1021/Bi00056A021  0.242
2001 Nakanishi T, Kekuda R, Fei YJ, Hatanaka T, Sugawara M, Martindale RG, Leibach FH, Prasad PD, Ganapathy V. Cloning and functional characterization of a new subtype of the amino acid transport system N. American Journal of Physiology. Cell Physiology. 281: C1757-68. PMID 11698233 DOI: 10.1152/Ajpcell.2001.281.6.C1757  0.242
2003 Chen Z, Kennedy DJ, Wake KA, Zhuang L, Ganapathy V, Thwaites DT. Structure, tissue expression pattern, and function of the amino acid transporter rat PAT2. Biochemical and Biophysical Research Communications. 304: 747-54. PMID 12727219 DOI: 10.1016/S0006-291X(03)00648-X  0.241
2005 Ganapathy V, Prasad PD. Role of transporters in placental transfer of drugs Toxicology and Applied Pharmacology. 207. PMID 15979662 DOI: 10.1016/J.Taap.2005.02.023  0.241
2001 Hatanaka T, Huang W, Martindale RG, Ganapathy V. Differential influence of cAMP on the expression of the three subtypes (ATA1, ATA2, and ATA3) of the amino acid transport system A. Febs Letters. 505: 317-20. PMID 11566196 DOI: 10.1016/S0014-5793(01)02848-4  0.24
1999 Seth P, Wu X, Huang W, Leibach FH, Ganapathy V. Mutations in novel organic cation transporter (OCTN2), an organic cation/carnitine transporter, with differential effects on the organic cation transport function and the carnitine transport function. The Journal of Biological Chemistry. 274: 33388-92. PMID 10559218 DOI: 10.1074/Jbc.274.47.33388  0.24
1998 Prasad P, Wang H, Huang W, Leibach F, Ganapathy V. Cloning of a cDNA encoding the human sodium-dependent vitamin transporter mediating the uptake of pantothenate, biotin and lipoate Placenta. 19: A57. DOI: 10.1016/S0143-4004(98)91266-8  0.239
2010 Fan X, Ross DD, Arakawa H, Ganapathy V, Tamai I, Nakanishi T. Impact of system L amino acid transporter 1 (LAT1) on proliferation of human ovarian cancer cells: a possible target for combination therapy with anti-proliferative aminopeptidase inhibitors. Biochemical Pharmacology. 80: 811-8. PMID 20510678 DOI: 10.1016/J.Bcp.2010.05.021  0.239
2014 Bhutia YD, Coothankandaswamy V, Cao S, Xu Y, Ganapathy V. Abstract 4340: The amino acid transporter SLC6A14 is an effective drug target for treatment of pancreatic cancer Cancer Research. 74: 4340-4340. DOI: 10.1158/1538-7445.Am2014-4340  0.238
2005 Naggar H, Van Ells TK, Ganapathy V, Smith SB. Regulation of Reduced-Folate Transporter-1 in Retinal Pigment Epithelial Cells by Folate Current Eye Research. 30: 35-44. DOI: 10.1080/02713680490894559A  0.237
2005 Naggar H, Van Ells TK, Ganapathy V, Smith SB. Regulation of Reduced-Folate Transporter-1 in Retinal Pigment Epithelial Cells by Folate Current Eye Research. 30: 35-44. DOI: 10.1080/02713680490894559  0.237
2011 Coothankandaswamy V, Elangovan S, Prasad PD, Thangaraju M, Ganapathy V. Abstract 2194: SLC5A8, a novel transporter with tumor suppressor function, mediates its effect through survivin depletion Cancer Research. 71: 2194-2194. DOI: 10.1158/1538-7445.Am2011-2194  0.237
2002 Bridges CC, El-Sherbeny A, Ola MS, Ganapathy V, Smith SB. Transcellular transfer of folate across the retinal pigment epithelium. Current Eye Research. 24: 129-38. PMID 12187485 DOI: 10.1076/Ceyr.24.2.129.8167  0.237
2003 Maddox DM, Manlapat A, Roon P, Prasad P, Ganapathy V, Smith SB. Reduced-folate carrier (RFC) is expressed in placenta and yolk sac, as well as in cells of the developing forebrain, hindbrain, neural tube, craniofacial region, eye, limb buds and heart. Bmc Developmental Biology. 3: 6. PMID 12887734 DOI: 10.1186/1471-213X-3-6  0.236
1982 Ganapathy V, Leibach FH. Peptide transport in rabbit kidney. Studies with l-carnosine Bba - Biomembranes. 691: 362-366. PMID 6814488 DOI: 10.1016/0005-2736(82)90427-8  0.236
2012 Ananth S, Thakkar SV, Gnana-Prakasam JP, Martin PM, Ganapathy PS, Smith SB, Ganapathy V. Transport of the synthetic opioid peptide DADLE ([D-Ala2,D-Leu5]-enkephalin) in neuronal cells. Journal of Pharmaceutical Sciences. 101: 154-63. PMID 21905028 DOI: 10.1002/Jps.22733  0.236
1995 Brandsch M, Ganapathy V, Leibach FH. H+-peptide cotransport in Madin-Darby canine kidney cells: Expression and calmodulin-dependent regulation American Journal of Physiology - Renal Fluid and Electrolyte Physiology. 268. PMID 7900838 DOI: 10.1152/Ajprenal.1995.268.3.F391  0.235
1986 Ganapathy V, Leibach FH. Carrier-mediated reabsorption of small peptides in renal proximal tubule American Journal of Physiology - Renal Fluid and Electrolyte Physiology. 251. PMID 3538905 DOI: 10.1152/ajprenal.1986.251.6.F945  0.235
1992 Ramamoorthy S, Leibach FH, Mahesh VB, Ganapathy V. Active transport of dopamine in human placental brush-border membrane vesicles. The American Journal of Physiology. 262: C1189-96. PMID 1590360 DOI: 10.1152/Ajpcell.1992.262.5.C1189  0.235
2016 Coothankandaswamy V, Cao S, Xu Y, Prasad PD, Singh PK, Reynolds CP, Yang S, Ogura J, Ganapathy V, Bhutia YD. Amino acid transporter SLC6A14 is a novel and effective drug target for pancreatic cancer. British Journal of Pharmacology. PMID 27747870 DOI: 10.1111/Bph.13616  0.235
2015 Bhutia YD, Babu E, Ganapathy V. Interferon-γ induces a tryptophan-selective amino acid transporter in human colonic epithelial cells and mouse dendritic cells. Biochimica Et Biophysica Acta. 1848: 453-62. PMID 25450809 DOI: 10.1016/J.Bbamem.2014.10.021  0.234
2006 Hu H, Endres CJ, Chang C, Umapathy NS, Lee EW, Fei YJ, Itagaki S, Swaan PW, Ganapathy V, Unadkat JD. Electrophysiological characterization and modeling of the structure activity relationship of the human concentrative nucleoside transporter 3 (hCNT3). Molecular Pharmacology. 69: 1542-53. PMID 16446384 DOI: 10.1124/Mol.105.018945  0.234
2011 Edwards N, Anderson CM, Gatfield KM, Jevons MP, Ganapathy V, Thwaites DT. Amino acid derivatives are substrates or non-transported inhibitors of the amino acid transporter PAT2 (slc36a2). Biochimica Et Biophysica Acta. 1808: 260-70. PMID 20691150 DOI: 10.1016/J.Bbamem.2010.07.032  0.233
2012 Itagaki S, Ganapathy V, Ho HT, Zhou M, Babu E, Wang J. Electrophysiological characterization of the polyspecific organic cation transporter plasma membrane monoamine transporter. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 40: 1138-43. PMID 22396231 DOI: 10.1124/Dmd.111.042432  0.232
1996 Mackenzie B, Fei YJ, Ganapathy V, Leibach FH. The human intestinal H+/oligopeptide cotransporter hPEPT1 transports differently-charged dipeptides with identical electrogenic properties. Biochimica Et Biophysica Acta. 1284: 125-8. PMID 8914574 DOI: 10.1016/S0005-2736(96)00170-8  0.231
1995 Liu W, Liang R, Ramamoorthy S, Fei YJ, Ganapathy ME, Hediger MA, Ganapathy V, Leibach FH. Molecular cloning of PEPT 2, a new member of the H+/peptide cotransporter family, from human kidney. Biochimica Et Biophysica Acta. 1235: 461-6. PMID 7756356 DOI: 10.1016/0005-2736(95)80036-F  0.231
2010 Bozard BR, Ganapathy PS, Duplantier J, Mysona B, Ha Y, Roon P, Smith R, Goldman ID, Prasad P, Martin PM, Ganapathy V, Smith SB. Molecular and biochemical characterization of folate transport proteins in retinal Müller cells. Investigative Ophthalmology & Visual Science. 51: 3226-35. PMID 20053979 DOI: 10.1167/Iovs.09-4833  0.231
1999 Kenney SP, Kekuda R, Prasad PD, Leibach FH, Devoe LD, Ganapathy V. Cannabinoid receptors and their role in the regulation of the serotonin transporter in human placenta. American Journal of Obstetrics and Gynecology. 181: 491-7. PMID 10454705 DOI: 10.1016/S0002-9378(99)70583-1  0.231
2004 Umapathy NS, Ganapathy V, Ganapathy ME. Transport of amino acid esters and the amino-acid-based prodrug valganciclovir by the amino acid transporter ATB 0,+ Pharmaceutical Research. 21: 1303-1310. PMID 15290873 DOI: 10.1023/B:Pham.0000033019.49737.28  0.23
1996 Kekuda R, Prasad P, Fei Y, Torres-Zamorano V, Leibach F, Ganapathy V. Cloning of neutral amino acid transporter B0 from a human placental choriocarcinoma cell line Placenta. 17: A24. DOI: 10.1016/s0143-4004(96)90157-5  0.23
1986 Balkovetz DF, Leibach FH, Mahesh VB, Devoe LD, Cragoe EJ, Ganapathy V. Na+-H+ exchanger of human placental brush-border membrane: identification and characterization. The American Journal of Physiology. 251: C852-60. PMID 3024497 DOI: 10.1152/ajpcell.1986.251.6.C852  0.23
2000 Ganapathy ME, Huang W, Rajan DP, Carter AL, Sugawara M, Iseki K, Leibach FH, Ganapathy V. β-Lactam antibiotics as substrates for OCTN2, an organic cation/carnitine transporter Journal of Biological Chemistry. 275: 1699-1707. PMID 10636865 DOI: 10.1074/Jbc.275.3.1699  0.23
1985 Ganapathy V, Burckhardt G, Leibach FH. Peptide transport in rabbit intestinal brush-border membrane vesicles studied with a potential-sensitive dye Bba - Biomembranes. 816: 234-240. PMID 3839134 DOI: 10.1016/0005-2736(85)90490-0  0.23
2018 Ogura J, Babu E, Miyauchi S, Ramachandran S, Nemeth E, Bhutia YD, Ganapathy V. Retraction Note: Identification of a novel Na-coupled Fe-citrate transport system, distinct from mammalian INDY, for uptake of citrate in mammalian cells. Scientific Reports. 8: 11021. PMID 30018353 DOI: 10.1038/S41598-018-28645-X  0.229
2001 Ramanathan S, Pooyan S, Stein S, Prasad PD, Wang J, Leibowitz MJ, Ganapathy V, Sinko PJ. Targeting the sodium-dependent multivitamin transporter (SMVT) for improving the oral absorption properties of a retro-inverso Tat nonapeptide. Pharmaceutical Research. 18: 950-6. PMID 11496954 DOI: 10.1023/A:1010932126662  0.229
1988 Miyamoto Y, Ganapathy V, Leibach FH. Transport of guanidine in rabbit intestinal brush-border membrane vesicles. The American Journal of Physiology. 255: G85-92. PMID 2839044 DOI: 10.1152/Ajpgi.1988.255.1.G85  0.229
1996 Torres-Zamorano V, Kekuda R, Leibach F, Ganapathy V. Tyrosine phosphorylation-dependent regulation of the amino acid transporter B) in JAR human placental choriocarcinoma cells Placenta. 17: A24. DOI: 10.1016/S0143-4004(96)90156-3  0.229
2006 Thangaraju M, Ananth S, Martin PM, Roon P, Smith SB, Sterneck E, Prasad PD, Ganapathy V. c/ebpdelta Null mouse as a model for the double knock-out of slc5a8 and slc5a12 in kidney. The Journal of Biological Chemistry. 281: 26769-73. PMID 16873376 DOI: 10.1074/Jbc.C600189200  0.228
2018 Ogura J, Babu E, Miyauchi S, Ramachandran S, Nemeth E, Bhutia YD, Ganapathy V. Identification of a novel Na+-coupled Fe3+-citrate transport system, distinct from mammalian INDY, for uptake of citrate in mammalian cells. Scientific Reports. 8: 2519. PMID 29410496 DOI: 10.1038/S41598-018-20620-W  0.227
2000 Fujita T, Kishida T, Okada N, Ganapathy V, Leibach FH, Yamamoto A. Interaction of kyotorphin and brain peptide transporter in synaptosomes prepared from rat cerebellum: implication of high affinity type H+/peptide transporter PEPT2 mediated transport system. Neuroscience Letters. 271: 117-20. PMID 10477116 DOI: 10.1016/S0304-3940(99)00540-6  0.227
1997 Ganapathy V, Leibach FH. Peptide transporters. Current Opinion in Nephrology and Hypertension. 5: 395-400. PMID 8937806 DOI: 10.1097/00041552-199609000-00003  0.227
2008 Thakkar SV, Miyauchi S, Prasad PD, Ganapathy V. Stimulation of Na+/Cl--coupled opioid peptide transport system in SK-N-SH cells by L-kyotorphin, an endogenous substrate for H+-coupled peptide transporter PEPT2. Drug Metabolism and Pharmacokinetics. 23: 254-62. PMID 18762712 DOI: 10.2133/Dmpk.23.254  0.227
1982 Ganapathy V, Leibach FH. Peptide transport in intestinal and renal brush border membrane vesicles Life Sciences. 30: 2137-2146. PMID 7050578 DOI: 10.1016/0024-3205(82)90287-9  0.226
2005 Ganapathy V, Miyauchi S. Transport systems for opioid peptides in mammalian tissues Aaps Journal. 7. PMID 16594637 DOI: 10.1208/Aapsj070482  0.226
1994 Prasad PD, Leibach FH, Mahesh VB, Ganapathy V. Relationship between thyroid hormone transport and neutral amino acid transport in JAR human choriocarcinoma cells. Endocrinology. 134: 574-81. PMID 8299556 DOI: 10.1210/Endo.134.2.8299556  0.226
2021 Sniegowski T, Korac K, Bhutia YD, Ganapathy V. SLC6A14 and SLC38A5 Drive the Glutaminolysis and Serine-Glycine-One-Carbon Pathways in Cancer. Pharmaceuticals (Basel, Switzerland). 14. PMID 33806675 DOI: 10.3390/ph14030216  0.226
2005 Sugawara M, Kato M, Kitakubo M, Takekuma Y, Ganapathy V, Miyazaki K. Inhibitory effects of basic drugs on the sodium-dependent transport of L-alanine via system B0 in the small intestine. Drug Metabolism and Pharmacokinetics. 18: 186-93. PMID 15618734 DOI: 10.2133/Dmpk.18.186  0.225
2010 Mazurek MP, Prasad PD, Gopal E, Fraser SP, Bolt L, Rizaner N, Palmer CP, Foster CS, Palmieri F, Ganapathy V, Stühmer W, Djamgoz MB, Mycielska ME. Molecular origin of plasma membrane citrate transporter in human prostate epithelial cells. Embo Reports. 11: 431-7. PMID 20448665 DOI: 10.1038/Embor.2010.51  0.225
1990 Cool DR, Leibach FH, Ganapathy V. Modulation of serotonin uptake kinetics by ions and ion gradients in human placental brush-border membrane vesicles. Biochemistry. 29: 1818-22. PMID 2331465 DOI: 10.1021/Bi00459A022  0.225
2020 Kou L, Yao Q, Zhang H, Chu M, Bhutia YD, Chen R, Ganapathy V. Transporter-Targeted Nano-Sized Vehicles for Enhanced and Site-Specific Drug Delivery. Cancers. 12. PMID 33019627 DOI: 10.3390/cancers12102837  0.225
1985 Ganapathy V, Leibach FH. Is intestinal peptide transport energized by a proton gradient? American Journal of Physiology - Gastrointestinal and Liver Physiology. 12.  0.225
2016 Luo Q, Gong P, Sun M, Kou L, Ganapathy V, Jing Y, He Z, Sun J. Transporter occluded-state conformation-induced endocytosis: Amino acid transporter ATB(0,+)-mediated tumor targeting of liposomes for docetaxel delivery for hepatocarcinoma therapy. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 27810556 DOI: 10.1016/J.Jconrel.2016.10.031  0.225
2018 Sugio K, Inoda D, Masuda M, Azumaya I, Sasaki S, Shimono K, Ganapathy V, Miyauchi S. Transport of 2,4-dichloro phenoxyacetic acid by human Na-coupled monocarboxylate transporter 1 (hSMCT1, SLC5A8). Drug Metabolism and Pharmacokinetics. PMID 30583944 DOI: 10.1016/J.Dmpk.2018.10.004  0.224
2000 Avissar NE, Miller J, Ganapathy V, Sax HC. Characterization of antibodies to intestinal NA+dependent neural amino acid transporter (B0) Gastroenterology. 118. DOI: 10.1016/S0016-5085(00)82351-3  0.224
1987 Silbernagl S, Ganapathy V, Leibach FH. H+ gradient-driven dipeptide reabsorption in proximal tubule of rat kidney. Studies in vivo and in vitro. The American Journal of Physiology. 253: F448-57. PMID 3631280 DOI: 10.1152/ajprenal.1987.253.3.F448  0.224
1997 Brandsch M, Brandsch C, Ganapathy ME, Chew CS, Ganapathy V, Leibach FH. Influence of proton and essential histidyl residues on the transport kinetics of the H+/peptide cotransport systems in intestine (PEPT 1) and kidney (PEPT 2). Biochimica Et Biophysica Acta. 1324: 251-62. PMID 9092712 DOI: 10.1016/S0005-2736(96)00231-3  0.223
1998 Wang H, Fei YJ, Ganapathy V, Leibach FH. Electrophysiological characteristics of the proton-coupled peptide transporter PEPT2 cloned from rat brain. American Journal of Physiology. Cell Physiology. 275: C967-C975. PMID 29585314 DOI: 10.1152/Ajpcell.1998.275.4.C967  0.223
1996 Prasad P, Fei Y, Leibach F, Ganapathy V. Direct evidence for functional coupling between human placental folate transporter and folate receptor in a heterologous expression system Placenta. 17: A24. DOI: 10.1016/S0143-4004(96)90158-7  0.223
1999 Wu X, Fei YJ, Huang W, Chancy C, Leibach FH, Ganapathy V. Identity of the F52F12.1 gene product in Caenorhabditis elegans as an organic cation transporter. Biochimica Et Biophysica Acta. 1418: 239-44. PMID 10209228 DOI: 10.1016/S0005-2736(99)00020-6  0.223
1989 Balkovetz DF, Tiruppathi C, Leibach FH, Mahesh VB, Ganapathy V. Evidence for an Imipramine-sensitive Serotonin Transporter in Human Placental Brush-border Membranes Journal of Biological Chemistry. 264: 2195-2198. DOI: 10.1016/s0021-9258(18)94161-x  0.222
1998 Fei YJ, Liu JC, Fujita T, Liang R, Ganapathy V, Leibach FH. Identification of a potential substrate binding domain in the mammalian peptide transporters PEPT1 and PEPT2 using PEPT1-PEPT2 and PEPT2-PEPT1 chimeras. Biochemical and Biophysical Research Communications. 246: 39-44. PMID 9600064 DOI: 10.1006/Bbrc.1998.8566  0.222
2004 George RL, Huang W, Naggar HA, Smith SB, Ganapathy V. Transport of N-acetylaspartate via murine sodium/dicarboxylate cotransporter NaDC3 and expression of this transporter and aspartoacylase II in ocular tissues in mouse. Biochimica Et Biophysica Acta. 1690: 63-9. PMID 15337171 DOI: 10.1016/J.Bbadis.2004.05.009  0.222
2011 Yang L, Karim R, Ganapathy V, Smith R. Fast, memory-efficient regular expression matching with NFA-OBDDs Computer Networks. 55: 3376-3393. DOI: 10.1016/J.Comnet.2011.07.002  0.222
2010 Karunakaran S, Schoenlein PV, Thangaraju M, Prasad PD, Ganapathy V. Abstract 4838: Alpha-methyltryptophan, a blocker of the amino acid transporter SLC6A14, induces autophagy and apoptosis in SLC6A14-positive breast cancer and colon cancer cell lines Cancer Research. 70: 4838-4838. DOI: 10.1158/1538-7445.Am10-4838  0.222
1991 Miyamoto Y, Thompson YG, Howard EF, Ganapathy V, Leibach FH. Functional expression of the intestinal peptide-proton co-transporter in Xenopus laevis oocytes. Journal of Biological Chemistry. 266: 4742-4745. DOI: 10.1016/s0021-9258(19)67711-2  0.221
1998 KEKUDA R, LEIBACH F, GANAPATHY V. Interleukin-1 receptors in human placenta and their role in the regulation of the serotonin transporter gent expression Journal of the Society For Gynecologic Investigation. 5: 121A-121A. DOI: 10.1016/S1071-5576(97)86413-1  0.221
2011 Babu E, Ananth S, Veeranan-Karmegam R, Coothankandaswamy V, Smith SB, Boettger T, Ganapathy V, Martin PM. Transport via SLC5A8 (SMCT1) is obligatory for 2-oxothiazolidine-4-carboxylate to enhance glutathione production in retinal pigment epithelial cells. Investigative Ophthalmology & Visual Science. 52: 5749-57. PMID 21508099 DOI: 10.1167/Iovs.10-6825  0.221
2002 Nelson DM, Smith SD, Furesz TC, Sadovsky Y, Ganapathy V, Parvin CA, Smith CH. Hypoxia reduces expression and function of system A amino acid transporters in cultured term human trophoblasts. American Journal of Physiology. Cell Physiology. 284: C310-5. PMID 12388062 DOI: 10.1152/Ajpcell.00253.2002  0.22
2004 Fujita T, Kishida T, Wada M, Okada N, Yamamoto A, Leibach FH, Ganapathy V. Functional characterization of brain peptide transporter in rat cerebral cortex: identification of the high-affinity type H+/peptide transporter PEPT2. Brain Research. 997: 52-61. PMID 14715149 DOI: 10.1016/J.Brainres.2003.10.049  0.219
2013 Kinebuchi Y, Butt S, Ganapathy V, Iftode L, Nakajima T. Monitoring integrity using limited local memory Ieee Transactions On Information Forensics and Security. 8: 1230-1242. DOI: 10.1109/Tifs.2013.2266095  0.219
2003 Hu H, Miyauchi S, Bridges CC, Smith SB, Ganapathy V. Identification of a novel Na+- and Cl--coupled transport system for endogenous opioid peptides in retinal pigment epithelium and induction of the transport system by HIV-1 Tat. The Biochemical Journal. 375: 17-22. PMID 12924983 DOI: 10.1042/Bj20031059  0.218
1988 Miyamoto Y, Coone JL, Ganapathy V, Leibach FH. Distribution and properties of the glycylsarcosine-transport system in rabbit renal proximal tubule. Studies with isolated brush-border-membrane vesicles. The Biochemical Journal. 249: 247-53. PMID 3342009 DOI: 10.1042/bj2490247  0.218
1990 Tiruppathi C, Kulanthaivel P, Ganapathy V, Leibach FH. Evidence for tripeptide/H+ co-transport in rabbit renal brush-border membrane vesicles. The Biochemical Journal. 268: 27-33. PMID 2160811 DOI: 10.1042/bj2680027  0.218
2011 Babu E, Ramachandran S, CoothanKandaswamy V, Elangovan S, Prasad PD, Ganapathy V, Thangaraju M. Role of SLC5A8, a plasma membrane transporter and a tumor suppressor, in the antitumor activity of dichloroacetate. Oncogene. 30: 4026-37. PMID 21499304 DOI: 10.1038/Onc.2011.113  0.217
1999 Ganapathy V, Prasad PD, Ganapathy ME, Leibach FH. Drugs of abuse and placental transport Advanced Drug Delivery Reviews. 38: 99-110. DOI: 10.1016/S0169-409X(99)00009-5  0.217
1983 Ganapathy V, Leibach FH. Role of pH gradient and membrane potential in dipeptide transport in intestinal and renal brush-border membrane vesicles from the rabbit. Studies with L-carnosine and glycyl-L-proline Journal of Biological Chemistry. 258: 14189-14192. PMID 6643475  0.216
1984 Ganapathy V, Burckhardt G, Leibach FH. Characteristics of glycylsarcosine transport in rabbit intestinal brush-border membrane vesicles. Journal of Biological Chemistry. 259: 8954-8959. DOI: 10.1016/s0021-9258(17)47248-6  0.216
2020 Sikder MOF, Sivaprakasam S, Brown TP, Thangaraju M, Bhutia YD, Ganapathy V. SLC6A14, a Na+/Cl--coupled amino acid transporter, functions as a tumor promoter in colon and is a target for Wnt signaling. The Biochemical Journal. PMID 32219372 DOI: 10.1042/Bcj20200099  0.216
1996 Ramamoorthy S, Liu W, Ma YY, Yang-Feng TL, Ganapathy V, Leibach FH. Proton/peptide cotransporter (PEPT 2) from human kidney: functional characterization and chromosomal localization. Biochimica Et Biophysica Acta. 1240: 1-4. PMID 7495840 DOI: 10.1016/0005-2736(95)00178-7  0.215
1999 Smith SB, Huang W, Chancy C, Ganapathy V. Regulation of the reduced-folate transporter by nitric oxide in cultured human retinal pigment epithelial cells. Biochemical and Biophysical Research Communications. 257: 279-83. PMID 10198203 DOI: 10.1006/Bbrc.1999.0452  0.215
2000 Ganapathy V, Ganapathy ME, Leibach FH. Chapter 10 Intestinal transport of peptides and amino acids Current Topics in Membranes. 50: 379-412.  0.215
2007 Gopal E, Miyauchi S, Martin PM, Ananth S, Srinivas SR, Smith SB, Prasad PD, Ganapathy V. Expression and functional features of NaCT, a sodium-coupled citrate transporter, in human and rat livers and cell lines. American Journal of Physiology. Gastrointestinal and Liver Physiology. 292: G402-8. PMID 16973915 DOI: 10.1152/Ajpgi.00371.2006  0.215
1991 Tiruppathi C, Ganapathy V, Leibach FH. Transport of peptides in renal brush border membrane vesicles. Suitability of 125I-labelled tyrosyl peptides as substrates. Biochimica Et Biophysica Acta. 1069: 14-20. PMID 1681904 DOI: 10.1016/0005-2736(91)90098-S  0.215
2006 Itagaki S, Gopal E, Zhuang L, Fei YJ, Miyauchi S, Prasad PD, Ganapathy V. Interaction of ibuprofen and other structurally related NSAIDs with the sodium-coupled monocarboxylate transporter SMCT1 (SLC5A8). Pharmaceutical Research. 23: 1209-16. PMID 16729224 DOI: 10.1007/S11095-006-0023-1  0.213
1992 Ramamoorthy S, Cool DR, Leibach FH, Mahesh VB, Ganapathy V. Reconstitution of the human placental 5-hydroxytryptamine transporter in a catalytically active form after detergent solubilization. The Biochemical Journal. 286: 89-95. PMID 1520288 DOI: 10.1042/Bj2860089  0.213
2008 Cresci G, Thangaraju M-, Browning D, Ganapathy V. 558 Sodium-Coupled Transport of Butyrate By SLC5A8 Mediates Tumor Suppression in the Colon Gastroenterology. 134: A-849. DOI: 10.1016/S0016-5085(08)63976-1  0.213
2004 Bridges CC, Hu H, Miyauchi S, Siddaramappa UN, Ganapathy ME, Ignatowicz L, Maddox DM, Smith SB, Ganapathy V. Induction of cystine-glutamate transporter xc- by human immunodeficiency virus type 1 transactivator protein tat in retinal pigment epithelium. Investigative Ophthalmology & Visual Science. 45: 2906-14. PMID 15326101 DOI: 10.1167/Iovs.03-1355  0.213
2006 Martin PM, Gopal E, Ananth S, Zhuang L, Itagaki S, Prasad BM, Smith SB, Prasad PD, Ganapathy V. Identity of SMCT1 (SLC5A8) as a neuron-specific Na+-coupled transporter for active uptake of L-lactate and ketone bodies in the brain. Journal of Neurochemistry. 98: 279-88. PMID 16805814 DOI: 10.1111/J.1471-4159.2006.03878.X  0.212
2015 Babu E, Bhutia YD, Ramachandran S, Gnana-Prakasam JP, Prasad PD, Thangaraju M, Ganapathy V. Deletion of the amino acid transporter Slc6a14 suppresses tumor growth in spontaneous mouse models of breast cancer. The Biochemical Journal. PMID 25967569 DOI: 10.1042/BJ20150437  0.212
2011 Chothe PP, Gnana-Prakasam JP, Ananth S, Martin PM, Kannan R, Hinton DR, Smith SB, Ganapathy V. Transport of hepcidin, an iron-regulatory peptide hormone, into retinal pigment epithelial cells via oligopeptide transporters and its relevance to iron homeostasis. Biochemical and Biophysical Research Communications. 405: 244-9. PMID 21219868 DOI: 10.1016/J.Bbrc.2011.01.018  0.211
2009 Gnana-Prakasam JP, Thangaraju M, Liu K, Ha Y, Martin PM, Smith SB, Ganapathy V. Absence of iron-regulatory protein Hfe results in hyperproliferation of retinal pigment epithelium: role of cystine/glutamate exchanger. The Biochemical Journal. 424: 243-52. PMID 19715555 DOI: 10.1042/Bj20090424  0.211
1998 Wu X, Prasad P, Leibach F, Ganapathy V. Cloning of a new organic cation transporter hOCTN2 from a human placental trophoblast cell line Placenta. 19: A57. DOI: 10.1016/S0143-4004(98)91268-1  0.211
1983 Ganapathy V, Leibach FH. Electrogenic transport of 5-oxoproline in rabbit renal brush-border membrane vesicles Effect of intravesicular potassium Bba - Biomembranes. 732: 32-40. PMID 6871198 DOI: 10.1016/0005-2736(83)90183-9  0.21
2006 Jansson N, Pettersson J, Haafiz A, Ericsson A, Palmberg I, Tranberg M, Ganapathy V, Powell TL, Jansson T. Down-regulation of placental transport of amino acids precedes the development of intrauterine growth restriction in rats fed a low protein diet. The Journal of Physiology. 576: 935-46. PMID 16916910 DOI: 10.1113/Jphysiol.2003.550004  0.21
2011 Tachikawa M, Murakami K, Martin PM, Hosoya K, Ganapathy V. Retinal transfer of nicotinate by H+ -monocarboxylate transporter at the inner blood-retinal barrier. Microvascular Research. 82: 385-90. PMID 21741392 DOI: 10.1016/J.Mvr.2011.06.009  0.21
2011 Karunakaran S, Ramachandran S, Coothankandaswamy V, Elangovan S, Babu E, Periyasamy-Thandavan S, Gurav A, Gnanaprakasam JP, Singh N, Schoenlein PV, Prasad PD, Thangaraju M, Ganapathy V. SLC6A14 (ATB0,+) protein, a highly concentrative and broad specific amino acid transporter, is a novel and effective drug target for treatment of estrogen receptor-positive breast cancer. The Journal of Biological Chemistry. 286: 31830-8. PMID 21771784 DOI: 10.1074/Jbc.M111.229518  0.209
2011 Ganapathy V. Drugs of abuse and human placenta. Life Sciences. 88: 926-30. PMID 20932493 DOI: 10.1016/J.Lfs.2010.09.015  0.209
1998 Torres-Zamorano V, Leibach FH, Ganapathy V. Sodium-dependent homo- and hetero-exchange of neutral amino acids mediated by the amino acid transporter ATB° Biochemical and Biophysical Research Communications. 245: 824-829. PMID 9588199 DOI: 10.1006/Bbrc.1998.8434  0.209
2001 Kannan R, Stolz A, Ji Q, Prasad PD, Ganapathy V. Vitamin C transport in human lens epithelial cells: evidence for the presence of SVCT2. Experimental Eye Research. 73: 159-65. PMID 11446766 DOI: 10.1006/Exer.2001.1024  0.208
2011 Gnana-Prakasam JP, Reddy SK, Veeranan-Karmegam R, Smith SB, Martin PM, Ganapathy V. Polarized distribution of heme transporters in retinal pigment epithelium and their regulation in the iron-overload disease hemochromatosis. Investigative Ophthalmology & Visual Science. 52: 9279-86. PMID 22058337 DOI: 10.1167/Iovs.11-8264  0.208
2009 Mycielska ME, Patel A, Rizaner N, Mazurek MP, Keun H, Patel A, Ganapathy V, Djamgoz MB. Citrate transport and metabolism in mammalian cells: prostate epithelial cells and prostate cancer. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 31: 10-20. PMID 19153992 DOI: 10.1002/Bies.080137  0.207
1981 Ganapathy V, Mendicino J, Pashley DH, Leibach FH. Carrier-mediated transport of glycyl-L-proline in renal brush border vesicles. Biochemical and Biophysical Research Communications. 97: 1133-9. PMID 7470140 DOI: 10.1016/0006-291X(80)91493-X  0.207
2007 Shekhawat PS, Srinivas SR, Matern D, Bennett MJ, Boriack R, George V, Xu H, Prasad PD, Roon P, Ganapathy V. Spontaneous development of intestinal and colonic atrophy and inflammation in the carnitine-deficient jvs (OCTN2(-/-)) mice. Molecular Genetics and Metabolism. 92: 315-24. PMID 17884651 DOI: 10.1016/J.Ymgme.2007.08.002  0.206
2009 Tachikawa M, Kasai Y, Yokoyama R, Fujinawa J, Ganapathy V, Terasaki T, Hosoya K. The blood-brain barrier transport and cerebral distribution of guanidinoacetate in rats: involvement of creatine and taurine transporters. Journal of Neurochemistry. 111: 499-509. PMID 19682207 DOI: 10.1111/J.1471-4159.2009.06332.X  0.206
1993 Ramamoorthy S, Bauman AL, Moore KR, Han H, Yang-Feng T, Chang AS, Ganapathy V, Blakely RD. Antidepressant- and cocaine-sensitive human serotonin transporter: molecular cloning, expression, and chromosomal localization. Proceedings of the National Academy of Sciences of the United States of America. 90: 2542-6. PMID 7681602 DOI: 10.1073/Pnas.90.6.2542  0.205
2017 Kou L, Yao Q, Sivaprakasam S, Luo Q, Sun Y, Fu Q, He Z, Sun J, Ganapathy V. Dual targeting of l-carnitine-conjugated nanoparticles to OCTN2 and ATB(0,+) to deliver chemotherapeutic agents for colon cancer therapy. Drug Delivery. 24: 1338-1349. PMID 28911246 DOI: 10.1080/10717544.2017.1377316  0.205
2000 Wu X, George RL, Huang W, Wang H, Conway SJ, Leibach FH, Ganapathy V. Structural and functional characteristics and tissue distribution pattern of rat OCTN1, an organic cation transporter, cloned from placenta. Biochimica Et Biophysica Acta. 1466: 315-27. PMID 10825452 DOI: 10.1016/S0005-2736(00)00189-9  0.205
2002 Jones CR, Srinivas SR, Devoe LD, Ganapathy V, Prasad PD. Inhibition of system A amino acid transport activity by ethanol in BeWo choriocarcinoma cells. American Journal of Obstetrics and Gynecology. 187: 209-16. PMID 12114912 DOI: 10.1067/Mob.2002.123896  0.205
2005 Ganapathy ME, Ganapathy V. Amino acid transporter ATB0,+ as a delivery system for drugs and prodrugs Current Drug Targets: Immune, Endocrine and Metabolic Disorders. 5: 357-364. PMID 16375689 DOI: 10.2174/156800805774912953  0.205
2021 Jaramillo-Martinez V, Ganapathy V, Urbatsch IL. A home run for human NaCT/SLC13A5/INDY: cryo-EM structure and homology model to predict transport mechanisms, inhibitor interactions and mutational defects. The Biochemical Journal. 478: 2051-2057. PMID 34101804 DOI: 10.1042/BCJ20210211  0.205
2004 Gupta N, Miyauchi S, Hu H, Herdman A, Podolsky R, Martin P, Mager S, Martindale R, Ganapathy V. The Arginine Transporter ATB(0,+) is Upregulated in Colorectal Cancer Endoscopy. 36. DOI: 10.1055/S-2004-824983  0.204
2010 Singh N, Thangaraju M, Prasad PD, Martin PM, Lambert NA, Boettger T, Offermanns S, Ganapathy V. Blockade of dendritic cell development by bacterial fermentation products butyrate and propionate through a transporter (Slc5a8)-dependent inhibition of histone deacetylases. The Journal of Biological Chemistry. 285: 27601-8. PMID 20601425 DOI: 10.1074/Jbc.M110.102947  0.204
2018 Kou L, Sun R, Ganapathy V, Yao Q, Chen R. Recent advances in drug delivery via the organic cation/carnitine transporter 2 (OCTN2/SLC22A5). Expert Opinion On Therapeutic Targets. PMID 30016594 DOI: 10.1080/14728222.2018.1502273  0.204
2019 Sikder MOF, Sivaprakasam S, Ganapathy V. Abstract 3585: Amino acid transporter SLC6A14: A novel drug target for colorectal cancer Cancer Research. DOI: 10.1158/1538-7445.Sabcs18-3585  0.203
2016 Nguyen H, Ganapathy V, Srivastava A, Vaidyanathan S. Exploring infrastructure support for app-based services on cloud platforms Computers and Security. 62: 177-192. DOI: 10.1016/J.Cose.2016.07.009  0.203
2018 Ganapathy V. Targeting the achilles heel of cancer: Nutrient transporters Drug Metabolism and Pharmacokinetics. 33: S5. DOI: 10.1016/J.Dmpk.2017.11.025  0.202
1998 PRASAD P, HUANG W, WANG H, LEIBACH F, GANAPATHY V. Transport mechanisms for vitamin C in the JAR human placental choriocarcinoma cell line Journal of the Society For Gynecologic Investigation. 5: 124A-124A. DOI: 10.1016/S1071-5576(97)86428-3  0.201
2015 Gurav A, Sivaprakasam S, Bhutia YD, Boettger T, Singh N, Ganapathy V. Slc5a8, a Na+-coupled high-affinity transporter for short-chain fatty acids, is a conditional tumour suppressor in colon that protects against colitis and colon cancer under low-fibre dietary conditions Biochemical Journal. 469: 267-278. DOI: 10.1042/BJ20150242  0.201
2011 Baliga A, Ganapathy V, Iftode L. Detecting kernel-level rootkits using data structure invariants Ieee Transactions On Dependable and Secure Computing. 8: 670-684. DOI: 10.1109/Tdsc.2010.38  0.201
1989 Miyamoto Y, Tiruppathi C, Ganapathy V, Leibach FH. Multiple transport systems for organic cations in renal brush-border membrane vesicles. The American Journal of Physiology. 256: F540-8. PMID 2539743 DOI: 10.1152/ajprenal.1989.256.4.F540  0.2
2000 Fei YJ, Romero MF, Krause M, Liu JC, Huang W, Ganapathy V, Leibach FH. A novel H+-coupled oligopeptide transporter (OPT3) from Caenorhabditis elegans with a predominant function as a H+ channel and an exclusive expression in neurons Journal of Biological Chemistry. 275: 9563-9571. PMID 10734106 DOI: 10.1074/jbc.275.13.9563  0.2
1993 Ramamoorthy S, Ainol L, Leibach F, Blakely R, Ganapathy V. Molecular cloning, expression, chromosomal localization, and regulation of the human placental taurine transporter Placenta. 14: A60. DOI: 10.1016/S0143-4004(05)80585-5  0.199
1990 Cool DR, Leibach FH, Ganapathy V. High-affinity paroxetine binding to the human placental serotonin transporter. The American Journal of Physiology. 259: C196-204. PMID 2143355 DOI: 10.1152/Ajpcell.1990.259.2.C196  0.199
2009 Ananth S, Karunakaran S, Martin PM, Nagineni CN, Hooks JJ, Smith SB, Prasad PD, Ganapathy V. Functional identification of a novel transport system for endogenous and synthetic opioid peptides in the rabbit conjunctival epithelial cell line CJVE. Pharmaceutical Research. 26: 1226-35. PMID 18781380 DOI: 10.1007/S11095-008-9709-X  0.199
2006 Ganapathy V, Fujita T. Identity of the high-affinity sodium/carboxylate cotransporter NaC3 as the N-acetyl-L-aspartate transporter Advances in Experimental Medicine and Biology.. 576. PMID 16802705 DOI: 10.1007/0-387-30172-0_5  0.199
2012 Coothan-Kandaswamy V, Elangovan S, Gopal E, Kim JH, Robertson K, Thangaraju M, Ganapathy V, Prasad PD. Abstract 17: Tumor-suppressive function of SLC5A8 in renal cancer cells Cancer Research. 72: 17-17. DOI: 10.1158/1538-7445.Am2012-17  0.198
2015 Ganapathy V, Gurav A, Singh N. Abstract 2037: The butyrate transporter SLC5A8 is a tumor suppressor in colon linked to dietary fiber content Cancer Research. 75: 2037-2037. DOI: 10.1158/1538-7445.Am2015-2037  0.198
1986 Miyamoto Y, Ganapathy V, Leibach FH. Proton gradient-coupled uphill transport of glycylsarcosine in rabbit renal brush-border membrane vesicles. Biochemical and Biophysical Research Communications. 132: 946-53. PMID 4074356 DOI: 10.1016/0006-291X(85)91899-6  0.196
1988 Balkovetz DF, Leibach FH, Mahesh VB, Ganapathy V. A proton gradient is the driving force for uphill transport of lactate in human placental brush-border membrane vesicles. Journal of Biological Chemistry. 263: 13823-13830. DOI: 10.1016/S0021-9258(18)68318-8  0.196
1993 Jayanthi LD, Prasad PD, Ramamoorthy S, Mahesh VB, Leibach FH, Ganapathy V. Sodium- and chloride-dependent, cocaine-sensitive, high-affinity binding of nisoxetine to the human placental norepinephrine transporter. Biochemistry. 32: 12178-85. PMID 8218295 DOI: 10.1021/Bi00096A030  0.195
2018 Kou L, Bhutia YD, Yao Q, He Z, Sun J, Ganapathy V. Transporter-Guided Delivery of Nanoparticles to Improve Drug Permeation across Cellular Barriers and Drug Exposure to Selective Cell Types. Frontiers in Pharmacology. 9: 27. PMID 29434548 DOI: 10.3389/Fphar.2018.00027  0.195
2000 Fei YJ, Sugawara M, Liu JC, Li HW, Ganapathy V, Ganapathy ME, Leibach FH. cDNA structure, genomic organization, and promoter analysis of the mouse intestinal peptide transporter PEPT1. Biochimica Et Biophysica Acta. 1492: 145-54. PMID 11004485 DOI: 10.1016/S0167-4781(00)00101-9  0.195
1996 Roque AS, Prasad PD, Bhatia JS, Leibach FH, Ganapathy V. Sodium-dependent high-affinity binding of carnitine to human placental brush border membranes. Biochimica Et Biophysica Acta. 1282: 274-82. PMID 8703983 DOI: 10.1016/0005-2736(96)00068-5  0.194
1994 Brandsch M, Leibach FH, Mahesh VB, Ganapathy V. Calmodulin-dependent modulation of pH sensitivity of the amino acid transport system L in human placental choriocarcinoma cells. Biochimica Et Biophysica Acta. 1192: 177-84. PMID 8018698 DOI: 10.1016/0005-2736(94)90116-3  0.194
2010 Kommareddi PK, Nair TS, Thang LV, Galano MM, Babu E, Ganapathy V, Kanazawa T, McHugh JB, Carey TE. Isoforms, expression, glycosylation, and tissue distribution of CTL2/SLC44A2. The Protein Journal. 29: 417-26. PMID 20665236 DOI: 10.1007/S10930-010-9268-Y  0.194
2006 Hatanaka T, Hatanaka Y, Tsuchida J, Ganapathy V, Setou M. Amino acid transporter ATA2 is stored at the trans-Golgi network and released by insulin stimulus in adipocytes. The Journal of Biological Chemistry. 281: 39273-84. PMID 17050538 DOI: 10.1074/Jbc.M604534200  0.194
2014 Blackburn AR, Hamrick MW, Chutkan N, Sangani R, Waller JL, Corpe R, Prasad PD, Isales CM, Ganapathy V, Fulzele S. Comparative analysis of sodium coupled vitamin C transporter 2 in human osteoarthritis grade 1 and grade 3 tissues. Bmc Musculoskeletal Disorders. 15: 9. PMID 24401033 DOI: 10.1186/1471-2474-15-9  0.193
2013 Sreekumar PG, Chothe P, Sharma KK, Baid R, Kompella U, Spee C, Kannan N, Manh C, Ryan SJ, Ganapathy V, Kannan R, Hinton DR. Antiapoptotic properties of α-crystallin-derived peptide chaperones and characterization of their uptake transporters in human RPE cells. Investigative Ophthalmology & Visual Science. 54: 2787-98. PMID 23532520 DOI: 10.1167/Iovs.12-11571  0.193
2012 Ramachandran S, Elangovan S, Pathania R, Prasad PD, Ganapathy V, Thangaraju M. Abstract 18: Slc5a8 inactivation is associated with mammary gland involution delay, early onset of mammary tumorigenesis and accelerated lung metastasis Cancer Research. 72: 18-18. DOI: 10.1158/1538-7445.Am2012-18  0.193
1996 Mackenzie B, Loo DD, Fei Y, Liu WJ, Ganapathy V, Leibach FH, Wright EM. Mechanisms of the human intestinal H+-coupled oligopeptide transporter hPEPT1. The Journal of Biological Chemistry. 271: 5430-7. PMID 8621398 DOI: 10.1074/Jbc.271.10.5430  0.192
1985 Ganapathy V, Pashley DH, Fonteles MC, Leibach FH. Peptidases and peptide transport in mammalian kidney. Contributions to Nephrology. 42: 10-8. PMID 6398188 DOI: 10.1159/000409956  0.191
1995 Liang R, Fei YJ, Prasad PD, Ramamoorthy S, Han H, Yang-Feng TL, Hediger MA, Ganapathy V, Leibach FH. Human intestinal H+/peptide cotransporter. Cloning, functional expression, and chromosomal localization. The Journal of Biological Chemistry. 270: 6456-63. PMID 7896779 DOI: 10.1074/Jbc.270.12.6456  0.191
2017 Kou L, Yao Q, Sun M, Wu C, Wang J, Luo Q, Wang G, Du Y, Fu Q, Wang J, He Z, Ganapathy V, Sun J. Cotransporting Ion is a Trigger for Cellular Endocytosis of Transporter-Targeting Nanoparticles: A Case Study of High-Efficiency SLC22A5 (OCTN2)-Mediated Carnitine-Conjugated Nanoparticles for Oral Delivery of Therapeutic Drugs. Advanced Healthcare Materials. PMID 28661032 DOI: 10.1002/Adhm.201700165  0.191
1983 Ganapathy V, Roesel RA, Howard JC, Leibach FH. Interaction of proline, 5-oxoproline, and pipecolic acid for renal transport in the rabbit. Journal of Biological Chemistry. 258: 2266-2272. DOI: 10.1016/s0021-9258(18)32917-x  0.191
1997 Ganapathy V, Leibach FH. Cloning and functional characterization of a system B(o)-like amino acid transporter Amino Acids. 13: 48.  0.191
1987 Miyamoto Y, Ganapathy V, Barlas A, Neubert K, Barth A, Leibach FH. Role of dipeptidyl peptidase IV in uptake of peptide nitrogen from beta-casomorphin in rabbit renal BBMV. The American Journal of Physiology. 252: F670-7. PMID 2882693 DOI: 10.1152/Ajprenal.1987.252.4.F670  0.188
1997 Bhatia J, Ganapathy V, Rossignol C, Leibach FH. Taurine And Glutamine Transport Is Increased In Jejunal Brush Border Membrane Vesicles After Short-Term Total Parenteral Nutrition In Rats 466 Pediatric Research. 41: 80-80. DOI: 10.1203/00006450-199704001-00486  0.188
1998 Prasad PD, Leibach FH, Ganapathy V. Transplacental transport of water-soluble vitamins Placenta. 19: 243-257. DOI: 10.1016/S0143-4004(98)80018-0  0.186
1981 Ganapathy V, Mendicino J, Leibach F. Transport of glycyl-L-proline into intestinal and renal brush border vesicles from rabbit. Journal of Biological Chemistry. 256: 118-124. DOI: 10.1016/s0021-9258(19)70106-9  0.186
2021 Jaramillo-Martinez V, Ganapathy V, Urbatsch I. Structural Insights and Classification of the Disease-Causing Mutations in Human Na+- Coupled Citrate Transporter (NACT) using a Homology Modeling Approach Biophysical Journal. 120: 27a. DOI: 10.1016/J.BPJ.2020.11.421  0.185
2019 Brown T, Ganapathy V. Lactate/GPR81 signaling and proton motive force in cancer: Role in angiogenesis, immune escape, nutrition, and Warburg phenomenon. Pharmacology & Therapeutics. 107451. PMID 31836453 DOI: 10.1016/J.Pharmthera.2019.107451  0.184
1999 Fei YJ, Nara E, Liu JC, Boyd CA, Ganapathy V, Leibach FH. Preferential recognition of zwitterionic dipeptides as transportable substrates by the high-affinity peptide transporter PEPT2. Biochimica Et Biophysica Acta. 1418: 344-51. PMID 10320685 DOI: 10.1016/S0005-2736(99)00046-2  0.183
2020 Kou L, Huang H, Lin X, Jiang X, Bao S, Luo Q, Sun J, Yao Q, Ganapathy V, Chen R. Endocytosis of ATB(SLC6A14)-targeted liposomes for drug delivery and its therapeutic application for pancreatic cancer. Expert Opinion On Drug Delivery. PMID 31990587 DOI: 10.1080/17425247.2020.1723544  0.182
1998 Bockman DE, Ganapathy V, Oblak TG, Leibach FH. Localization of peptide transporter in nuclei and lysosomes of the pancreas. International Journal of Pancreatology : Official Journal of the International Association of Pancreatology. 22: 221-5. PMID 9444554 DOI: 10.1007/Bf02788388  0.182
2005 Gupta N, Miyauchi S, Martindale RG, Herdman AV, Podolsky R, Miyake K, Mager S, Prasad PD, Ganapathy ME, Ganapathy V. Upregulation of the amino acid transporter ATB0,+ (SLC6A14) in colorectal cancer and metastasis in humans. Biochimica Et Biophysica Acta. 1741: 215-23. PMID 15905073 DOI: 10.1016/J.Bbadis.2005.04.002  0.182
2020 Kopel J, Higuchi K, Ristic B, Sato T, Ramachandran S, Ganapathy V. The Hepatic Plasma Membrane Citrate Transporter NaCT (SLC13A5) as a Molecular Target for Metformin. Scientific Reports. 10: 8536. PMID 32444674 DOI: 10.1038/S41598-020-65621-W  0.181
2014 Smith SB, Ganapathy PS, Bozard RB, Ganapathy V. Folate Transport in Retina and Consequences on Retinal Structure and Function of Hyperhomocysteinemia Handbook of Nutrition, Diet and the Eye. 349-359. DOI: 10.1016/B978-0-12-401717-7.00035-6  0.181
2018 Mycielska ME, Dettmer-Wilde K, Rümmele P, Schmidt KM, Prehn C, Milenkovic V, Jagla W, Madej MG, Lantow M, Schladt MT, Cecil A, Koehl GE, Eggenhofer E, Wachsmuth C, Ganapathy V, et al. Extracellular citrate affects critical elements of cancer cell metabolism and supports cancer development in vivo. Cancer Research. PMID 29510993 DOI: 10.1158/0008-5472.Can-17-2959  0.18
1991 Ramamoorthy S, Tiruppathi C, Nair CN, Mahesh VB, Leibach FH, Ganapathy V. Relative sensitivity to inhibition by cimetidine and clonidine differentiates between the two types of Na(+)-H+ exchangers in cultured cells. The Biochemical Journal. 280: 317-22. PMID 1660711 DOI: 10.1042/Bj2800317  0.179
1991 Kulanthaivel P, Miyamoto Y, Mahesh VB, Leibach FH, Ganapathy V. Inactivation of taurine transporter by calcium in purified human placental brush border membrane vesicles. Placenta. 12: 327-40. PMID 1946243 DOI: 10.1016/0143-4004(91)90341-C  0.179
1992 Ramamoorthy S, Prasad P, Kulanthaivel P, Leibach F, Blakely R, Ganapathy V. Expression of the cocaine-sensitive norepinephrine transporter in the human placental syncytiotrophoblast Placenta. 13: A53. DOI: 10.1016/0143-4004(92)90168-S  0.179
1991 Miyamoto Y, Kulanthaivel P, Ganapathy V, Whitford GM, Leibach FH. Calcium-induced inhibition of taurine transport in brush-border membrane vesicles from rabbit small intestine. Biochimica Et Biophysica Acta. 1030: 189-94. PMID 2124507 DOI: 10.1016/0005-2736(90)90294-X  0.178
1990 Tiruppathi C, Ganapathy V, Leibach F. Kinetic evidence for a common transporter for glycylsarcosine and phenylalanylprolylalanine in renal brush-border membrane vesicles. Journal of Biological Chemistry. 265: 14870-14874. DOI: 10.1016/s0021-9258(18)77195-0  0.178
1992 Ramamoorthy S, Leibach FH, Mahesh VB, Ganapathy V. Modulation of the activity of amino acid transport system L by phorbol esters and calmodulin antagonists in a human placental choriocarcinoma cell line. Biochimica Et Biophysica Acta. 1136: 181-8. PMID 1324010 DOI: 10.1016/0167-4889(92)90255-A  0.177
1980 Ganapathy V, Radhakrishnan AN. Sodium-dependent inhibition of amino acid and dipeptide transport by harmaline in monkey small intestine Biochemical Pharmacology. 29: 713-716. DOI: 10.1016/0006-2952(80)90545-6  0.176
1994 Prasad PD, Leibach FH, Mahesh VB, Ganapathy V. Human placenta as a target organ for cocaine action: interaction of cocaine with the placental serotonin transporter. Placenta. 15: 267-78. PMID 8066050 DOI: 10.1016/0143-4004(94)90018-3  0.176
2009 Maran RR, Thomas A, Roth M, Sheng Z, Esterly N, Pinson D, Gao X, Zhang Y, Ganapathy V, Gonzalez FJ, Guo GL. Farnesoid X receptor deficiency in mice leads to increased intestinal epithelial cell proliferation and tumor development. The Journal of Pharmacology and Experimental Therapeutics. 328: 469-77. PMID 18981289 DOI: 10.1124/Jpet.108.145409  0.176
2006 Dun Y, Mysona B, Van Ells T, Amarnath L, Ola MS, Ganapathy V, Smith SB. Expression of the cystine-glutamate exchanger (xc-) in retinal ganglion cells and regulation by nitric oxide and oxidative stress. Cell and Tissue Research. 324: 189-202. PMID 16609915 DOI: 10.1007/S00441-005-0116-X  0.174
2003 Gupta N, Miyauchi S, Martindale R, Herdman A, Hu H, Podolsky R, Mager S, Ganapathy V. Upregulation of the arginine transporter Atb(0,+) in colorectal cancer Journal of Surgical Research. 114: 268. DOI: 10.1016/J.Jss.2003.08.218  0.173
2003 Ganapathy V, Miyauchi S. Peptide transporters: Physiological function and potential for use as a drug delivery system American Pharmaceutical Review. 6: 14-19.  0.172
1979 Ganapathy V, Radhakrishnan AN. Interaction of amino acids with glycyl-L-leucine hydrolysis and transport in monkey small intestine Clinical Science. 57: 521-527. PMID 117966  0.172
1992 Sivakami S, Ganapathy V, Leibach FH, Miyamoto Y. The gamma-aminobutyric acid transporter and its interaction with taurine in the apical membrane of the bovine retinal pigment epithelium. The Biochemical Journal. 391-7. PMID 1575683 DOI: 10.1042/BJ2830391  0.172
2013 Makala L, Promsote W, Li B, Ganapathy V, Pamela M, Pace BS. Monomethylfumarate (MMF), a Novel Inducer Of Fetal Hemoglobin In Human Erythroid Progenitors and Retinal Pigment Epithelial Cells Blood. 122: 317-317. DOI: 10.1182/Blood.V122.21.317.317  0.171
2013 Fulzele S, Chothe P, Sangani R, Chutkan N, Hamrick M, Bhattacharyya M, Prasad PD, Zakhary I, Bowser M, Isales C, Ganapathy V. Sodium-dependent vitamin C transporter SVCT2: expression and function in bone marrow stromal cells and in osteogenesis. Stem Cell Research. 10: 36-47. PMID 23089627 DOI: 10.1016/J.Scr.2012.08.004  0.17
2009 Thangaraju M, Cresci GA, Liu K, Ananth S, Gnanaprakasam JP, Browning DD, Mellinger JD, Smith SB, Digby GJ, Lambert NA, Prasad PD, Ganapathy V. GPR109A is a G-protein-coupled receptor for the bacterial fermentation product butyrate and functions as a tumor suppressor in colon. Cancer Research. 69: 2826-32. PMID 19276343 DOI: 10.1158/0008-5472.Can-08-4466  0.17
2009 Mysona B, Dun Y, Duplantier J, Ganapathy V, Smith SB. Effects of hyperglycemia and oxidative stress on the glutamate transporters GLAST and system xc- in mouse retinal Müller glial cells. Cell and Tissue Research. 335: 477-88. PMID 19156441 DOI: 10.1007/S00441-008-0742-1  0.169
2000 Brust P, Friedrich A, Krizbai IA, Bergmann R, Roux F, Ganapathy V, Johannsen B. Functional expression of the serotonin transporter in immortalized rat brain microvessel endothelial cells Journal of Neurochemistry. 74: 1241-1248. PMID 10693957 DOI: 10.1046/J.1471-4159.2000.741241.X  0.168
1990 Kulanthaivel P, Simon BJ, Leibach FH, Mahesh VB, Ganapathy V. An essential role for vicinal dithiol groups in the catalytic activity of the human placental Na(+)-H+ exchanger. Biochimica Et Biophysica Acta. 1024: 385-9. PMID 2162208 DOI: 10.1016/0005-2736(90)90369-Y  0.168
1994 Reinach P, Ganapathy V, Torres-Zamorano V. A Na:H exchanger subtype mediates volume regulation in bovine corneal epithelial cells Advances in Experimental Medicine and Biology. 350: 105-110. PMID 8030460 DOI: 10.1007/978-1-4615-2417-5_18  0.168
2012 Gnana-Prakasam JP, Tawfik A, Romej M, Ananth S, Martin PM, Smith SB, Ganapathy V. Iron-mediated retinal degeneration in haemojuvelin-knockout mice. The Biochemical Journal. 441: 599-608. PMID 21943374 DOI: 10.1042/Bj20111148  0.167
1987 Tiruppathi C, Ganapathy V, Leibach FH. Development of dipeptide transport in rat renal brush border membranes: studies with glycylsarcosine Pediatric Research. 22: 641-646. PMID 2829104 DOI: 10.1203/00006450-198712000-00005  0.167
1999 Rajan DP, Kekuda R, Huang W, Wang H, Devoe LD, Leibach FH, Prasad PD, Ganapathy V. Cloning and expression of a b(0,+)-like amino acid transporter functioning as a heterodimer with 4F2hc instead of rBAT. A new candidate gene for cystinuria. The Journal of Biological Chemistry. 274: 29005-10. PMID 10506149 DOI: 10.1074/Jbc.274.41.29005  0.167
1997 Kekuda R, Prasad PD, Fei YJ, Leibach FH, Ganapathy V. Cloning and functional expression of the human type 1 sigma receptor (hSigmaR1). Biochemical and Biophysical Research Communications. 229: 553-8. PMID 8954936 DOI: 10.1006/Bbrc.1996.1842  0.166
2013 Lewerenz J, Hewett SJ, Huang Y, Lambros M, Gout PW, Kalivas PW, Massie A, Smolders I, Methner A, Pergande M, Smith SB, Ganapathy V, Maher P. The cystine/glutamate antiporter system x(c)(-) in health and disease: from molecular mechanisms to novel therapeutic opportunities. Antioxidants & Redox Signaling. 18: 522-55. PMID 22667998 DOI: 10.1089/Ars.2011.4391  0.166
1992 Prasad P, Leibach F, Mahesh V, Ganapathy V. Specific interaction of 5-(N-methyl-N-isobutyl)amiloride with the organic cation-proton antiporter in human placental brush-border membrane vesicles. Transport and binding. Journal of Biological Chemistry. 267: 23632-23639. DOI: 10.1016/s0021-9258(18)35885-x  0.166
1987 Ganapathy V, Balkovetz DF, Ganapathy ME, Mahesh VB, Devoe LD, Leibach FH. Evidence for histidyl and carboxy groups at the active site of the human placental Na+-H+ exchanger. The Biochemical Journal. 245: 473-7. PMID 2822022 DOI: 10.1042/bj2450473  0.165
2013 Ganapathy V, Thangaraju M, Prasad PD, Martin PM, Singh N. Transporters and receptors for short-chain fatty acids as the molecular link between colonic bacteria and the host. Current Opinion in Pharmacology. 13: 869-74. PMID 23978504 DOI: 10.1016/J.Coph.2013.08.006  0.165
1999 Tamai I, Nakanishi T, Nakahara H, Sai Y, Ganapathy V, Leibach FH, Tsuji A. Improvement of L-dopa absorption by dipeptidyl derivation, utilizing peptide transporter PepT1. Journal of Pharmaceutical Sciences. 87: 1542-6. PMID 10189264 DOI: 10.1021/Js980186O  0.165
1983 Ganapathy V, Leibach FH. Role of pH gradient and membrane potential in dipeptide transport in intestinal and renal brush-border membrane vesicles from the rabbit. Studies with L-carnosine and glycyl-L-proline. Journal of Biological Chemistry. 258: 14189-14192. DOI: 10.1016/s0021-9258(17)43843-9  0.164
2011 Ganapathy V, Karunakaran S, Ramachandran S, Babu E, Elangovan S, Periaswamy-Thandavan S, Schoenlein PV, Gurav A, Singh N, Prasad PD, Thangaraju M. Abstract 4459: a-Methyltryptophan (a-MT) inhibits estrogen receptor (ER)-positive breast cancer growth through blockade of SLC6A14 Cancer Research. 71: 4459-4459. DOI: 10.1158/1538-7445.Am2011-4459  0.163
2000 Rajan DP, Huang W, Kekuda R, George RL, Wang J, Conway SJ, Devoe LD, Leibach FH, Prasad PD, Ganapathy V. Differential influence of the 4F2 heavy chain and the protein related to b(0,+) amino acid transport on substrate affinity of the heteromeric b(0,+) amino acid transporter. The Journal of Biological Chemistry. 275: 14331-5. PMID 10799513 DOI: 10.1074/Jbc.275.19.14331  0.163
2012 Wang R, Kwon IK, Thangaraju M, Singh N, Liu K, Jay P, Hofmann F, Ganapathy V, Browning DD. Type 2 cGMP-dependent protein kinase regulates proliferation and differentiation in the colonic mucosa. American Journal of Physiology. Gastrointestinal and Liver Physiology. 303: G209-19. PMID 22556146 DOI: 10.1152/Ajpgi.00500.2011  0.162
2020 Cai A, Zheng H, Chen Z, Lin X, Li C, Yao Q, Bhutia YD, Ganapathy V, Chen R, Kou L. Synergism between SLC6A14 blockade and gemcitabine in pancreactic cancer: A 1H-NMR-based metabolomic study in pancreatic cancer cells. The Biochemical Journal. PMID 32379301 DOI: 10.1042/Bcj20200275  0.162
2005 Thongsong B, Subramanian RK, Ganapathy V, Prasad PD. Inhibition of amino acid transport system a by interleukin-1beta in trophoblasts. Journal of the Society For Gynecologic Investigation. 12: 495-503. PMID 16202926 DOI: 10.1016/J.Jsgi.2005.06.008  0.162
1990 Miyamoto Y, Nakamura H, Hoshi T, Ganapathy V, Leibach FH. Uphill transport of beta-alanine in intestinal brush-border membrane vesicles. The American Journal of Physiology. 259: G372-9. PMID 2119146 DOI: 10.1152/ajpgi.1990.259.3.G372  0.161
2009 Thangaraju M, Carswell KN, Prasad PD, Ganapathy V. Colon cancer cells maintain low levels of pyruvate to avoid cell death caused by inhibition of HDAC1/HDAC3. The Biochemical Journal. 417: 379-89. PMID 18789002 DOI: 10.1042/Bj20081132  0.161
2012 Bhutia YD, Singh N, Ganapathy V. Abstract 26: Deletion of Slc5a8 in mice promotes metabolic syndrome, colonic inflammation, and colon cancer: A phenomenon dependent on dietary fiber content Cancer Research. 72: 26-26. DOI: 10.1158/1538-7445.Am2012-26  0.16
2018 Ristic B, Sivaprakasam S, Ogura J, Ganapathy V. Abstract 4477: Downregulation of ABCG2 expression in colitis and colon cancer: Relevance to iron overload, hemochromatosis and p53, and therapeutic use of carbidopa to reverse the downregulation Cancer Research. 78: 4477-4477. DOI: 10.1158/1538-7445.Am2018-4477  0.16
1992 Kulanthaivel P, Furesz TC, Moe AJ, Smith CH, Mahesh VB, Leibach FH, Ganapathy V. Human placental syncytiotrophoblast expresses two pharmacologically distinguishable types of Na(+)-H+ exchangers, NHE-1 in the maternal-facing (brush border) membrane and NHE-2 in the fetal-facing (basal) membrane. The Biochemical Journal. 284: 33-8. PMID 1318024 DOI: 10.1042/bj2840033  0.159
2012 Bardhan K, Ganapathy V, Liu K. Abstract 3140: Constitutive and regulated expression of GPR109A by DNA methylation and IFN-γ in human colon carcinoma cells Cancer Research. 72: 3140-3140. DOI: 10.1158/1538-7445.Am2012-3140  0.159
2020 Ristic B, Sivaprakasam S, Narayanan M, Ganapathy V. Hereditary hemochromatosis disrupts uric acid homeostasis and causes hyperuricemia via altered expression/activity of xanthine oxidase and ABCG2. The Biochemical Journal. PMID 32239172 DOI: 10.1042/Bcj20190873  0.158
2020 Kopel J, Grooms A, Ganapathy V, Clothier J. Metformin, valproic acid, and starvation induce seizures in a patient with partial SLC13A5 deficiency: a case of pharmaco-synergistic heterozygosity. Psychiatric Genetics. PMID 33290383 DOI: 10.1097/YPG.0000000000000269  0.158
2010 Cresci GA, Thangaraju M, Mellinger JD, Liu K, Ganapathy V. Colonic gene expression in conventional and germ-free mice with a focus on the butyrate receptor GPR109A and the butyrate transporter SLC5A8. Journal of Gastrointestinal Surgery : Official Journal of the Society For Surgery of the Alimentary Tract. 14: 449-61. PMID 20033346 DOI: 10.1007/S11605-009-1045-X  0.157
2016 Bhutia YD, Babu E, Ganapathy V. Re-programming tumour cell metabolism to treat cancer: no lone target for lonidamine. The Biochemical Journal. 473: 1503-6. PMID 27234586 DOI: 10.1042/Bcj20160068  0.157
1986 Miyamoto Y, Ganapathy V, Leibach FH. Identification of histidyl and thiol groups at the active site of rabbit renal dipeptide transporter. Journal of Biological Chemistry. 261: 16133-16140. DOI: 10.1016/s0021-9258(18)66688-8  0.156
2004 Brust P, Vorwieger G, Walter B, Füchtner F, Stark H, Kuwabara H, Herzau M, Opfermann T, Steinbach J, Ganapathy V, Bauer R. The influx of neutral amino acids into the porcine brain during development: a positron emission tomography study. Brain Research. Developmental Brain Research. 152: 241-53. PMID 15351512 DOI: 10.1016/J.Devbrainres.2004.07.002  0.156
2018 Shekhawat PS, Sonne S, Matern D, Ganapathy V. Embryonic lethality in mice due to carnitine transporter OCTN2 defect and placental carnitine deficiency. Placenta. 69: 71-73. PMID 30213487 DOI: 10.1016/J.Placenta.2018.06.312  0.156
2000 Ogonowski AA, Kaesemeyer WH, Jin L, Ganapathy V, Leibach FH, Caldwell RW. Effects of NO donors and synthase agonists on endothelial cell uptake of L-Arg and superoxide production. American Journal of Physiology. Cell Physiology. 278: C136-43. PMID 10644521 DOI: 10.1152/Ajpcell.2000.278.1.C136  0.156
2005 Jiang G, Zhuang L, Miyauchi S, Miyake K, Fei YJ, Ganapathy V. A Na+/Cl- -coupled GABA transporter, GAT-1, from Caenorhabditis elegans: structural and functional features, specific expression in GABA-ergic neurons, and involvement in muscle function. The Journal of Biological Chemistry. 280: 2065-77. PMID 15542610 DOI: 10.1074/Jbc.M408470200  0.155
1998 He H, Ganapathy V, Isales CM, Whitford GM. pH-dependent fluoride transport in intestinal brush border membrane vesicles Biochimica Et Biophysica Acta - Biomembranes. 1372: 244-254. PMID 9675300 DOI: 10.1016/S0005-2736(98)00064-9  0.154
1986 Ganapathy ME, Leibach FH, Mahesh VB, Devoe LD, Ganapathy V. Interaction of clonidine with human placental Na+ -H+ exchanger. Biochemical Pharmacology. 35: 3989-94. PMID 3022744 DOI: 10.1016/0006-2952(86)90016-X  0.153
1990 Tiruppathi C, Miyamoto Y, Ganapathy V, Roesel RA, Whitford GM, Leibach FH. Hydrolysis and transport of proline-containing peptides in renal brush-border membrane vesicles from dipeptidyl peptidase IV-positive and dipeptidyl peptidase IV-negative rat strains. Journal of Biological Chemistry. 265: 1476-1483. DOI: 10.1016/S0021-9258(19)40041-0  0.153
1993 Torres-Zamorano V, Ganapathy V, Reinach P. Characterization and subtype identification of the na+-h+ exchanger in bovine corneal epithelium Current Eye Research. 12: 69-76. PMID 8382145 DOI: 10.3109/02713689308999498  0.152
2006 Thangaraju M, Gopal E, Martin PM, Ananth S, Smith SB, Prasad PD, Sterneck E, Ganapathy V. SLC5A8 triggers tumor cell apoptosis through pyruvate-dependent inhibition of histone deacetylases. Cancer Research. 66: 11560-4. PMID 17178845 DOI: 10.1158/0008-5472.Can-06-1950  0.151
2018 Ramachandran S, Brown T, Ganapathy V. Abstract 2402: Autocrine and paracrine role of tumor derived lactic acid in tumor growth and metastasis and in tumor cell nutrition Cancer Research. 78: 2402-2402. DOI: 10.1158/1538-7445.Am2018-2402  0.151
2010 Ramachandran S, Elangovan S, Prasad PD, Ganapathy V, Thangaraju M. Abstract LB-236: Differential regulation of STAT3 in mammary gland involution as well as in mammary tumorigeneis Cancer Research. 70. DOI: 10.1158/1538-7445.Am10-Lb-236  0.15
2020 Haferkamp S, Drexler K, Federlin M, Schlitt HJ, Berneburg M, Adamski J, Gaumann A, Geissler EK, Ganapathy V, Parkinson EK, Mycielska ME. Extracellular Citrate Fuels Cancer Cell Metabolism and Growth. Frontiers in Cell and Developmental Biology. 8: 602476. PMID 33425906 DOI: 10.3389/fcell.2020.602476  0.15
2012 Zimmerman MA, Singh N, Martin PM, Thangaraju M, Ganapathy V, Waller JL, Shi H, Robertson KD, Munn DH, Liu K. Butyrate suppresses colonic inflammation through HDAC1-dependent Fas upregulation and Fas-mediated apoptosis of T cells. American Journal of Physiology. Gastrointestinal and Liver Physiology. 302: G1405-15. PMID 22517765 DOI: 10.1152/Ajpgi.00543.2011  0.15
2015 Wang J, Shanmugam A, Markand S, Zorrilla E, Ganapathy V, Smith SB. Sigma 1 receptor regulates the oxidative stress response in primary retinal Müller glial cells via NRF2 signaling and system xc(-), the Na(+)-independent glutamate-cystine exchanger. Free Radical Biology & Medicine. 86: 25-36. PMID 25920363 DOI: 10.1016/J.Freeradbiomed.2015.04.009  0.149
1990 Kulanthaivel P, Simon BJ, Burckhardt G, Mahesh VB, Leibach FH, Ganapathy V. The ATP-binding site of the human placental H+ pump contains essential tyrosyl residues. Biochemistry. 29: 10807-13. PMID 2148692 DOI: 10.1021/Bi00500A013  0.147
2004 Shekhawat PS, Yang HS, Bennett MJ, Carter AL, Matern D, Tamai I, Ganapathy V. Carnitine content and expression of mitochondrial β-oxidation enzymes in placentas of wild-type (OCTN2+/+) and OCTN2 null (OCTN2 -/-) mice Pediatric Research. 56: 323-328. PMID 15240869 DOI: 10.1203/01.Pdr.0000134252.02876.55  0.147
2015 Bardhan K, Paschall AV, Yang D, Chen MR, Simon PS, Bhutia YD, Martin PM, Thangaraju M, Browning DD, Ganapathy V, Heaton CM, Gu K, Lee JR, Liu K. IFNγ Induces DNA Methylation-Silenced GPR109A Expression via pSTAT1/p300 and H3K18 Acetylation in Colon Cancer. Cancer Immunology Research. 3: 795-805. PMID 25735954 DOI: 10.1158/2326-6066.Cir-14-0164  0.147
2016 Ganapathy V, Babu E, Ramachandran S, Bhutia YD. Abstract 1015: Repurposing the FDA-approved drug carbidopa to treat human cancers Cancer Research. 76: 1015-1015. DOI: 10.1158/1538-7445.Am2016-1015  0.146
2017 Kou L, Hou Y, Yao Q, Guo W, Wang G, Wang M, Fu Q, He Z, Ganapathy V, Sun J. L-Carnitine-conjugated nanoparticles to promote permeation across blood-brain barrier and to target glioma cells for drug delivery via the novel organic cation/carnitine transporter OCTN2. Artificial Cells, Nanomedicine, and Biotechnology. 1-12. PMID 28974108 DOI: 10.1080/21691401.2017.1384385  0.146
2014 Ananth S, Gnana-Prakasam JP, Bhutia YD, Veeranan-Karmegam R, Martin PM, Smith SB, Ganapathy V. Regulation of the cholesterol efflux transporters ABCA1 and ABCG1 in retina in hemochromatosis and by the endogenous siderophore 2,5-dihydroxybenzoic acid. Biochimica Et Biophysica Acta. 1842: 603-12. PMID 24462739 DOI: 10.1016/J.Bbadis.2014.01.010  0.145
2008 Gnana-Prakasam JP, Martin PM, Mysona BA, Roon P, Smith SB, Ganapathy V. Hepcidin expression in mouse retina and its regulation via lipopolysaccharide/Toll-like receptor-4 pathway independent of Hfe. The Biochemical Journal. 411: 79-88. PMID 18042040 DOI: 10.1042/Bj20071377  0.144
2009 Kashiwagi H, Yamazaki K, Takekuma Y, Ganapathy V, Sugawara M. Regulatory mechanisms of SNAT2, an amino acid transporter, in L6 rat skeletal muscle cells by insulin, osmotic shock and amino acid deprivation. Amino Acids. 36: 219-30. PMID 18330498 DOI: 10.1007/S00726-008-0050-9  0.144
2010 Elangovan S, Prasad PD, Ganapathy V, Thangaraju M. Abstract 1100: p53 blocks TGFβ-induced breast cancer metastasis by downregulating angiopoietin-like 4 Cancer Research. 70: 1100-1100. DOI: 10.1158/1538-7445.Am10-1100  0.143
2008 Kwon IK, Schoenlein PV, Delk J, Liu K, Thangaraju M, Dulin NO, Ganapathy V, Berger FG, Browning DD. Expression of cyclic guanosine monophosphate-dependent protein kinase in metastatic colon carcinoma cells blocks tumor angiogenesis. Cancer. 112: 1462-70. PMID 18260092 DOI: 10.1002/Cncr.23334  0.142
2013 Martin PM, Gambhir D, Promsote W, Ganapathy V, Moore-Hill D. Expression of the Niacin Receptor GPR109A in Retina: More than Meets the Eye? Clinical and Experimental Pharmacology. 3: 1-6. DOI: 10.4172/2161-1459.S3-003  0.142
1992 Simon BJ, Kulanthaivel P, Burckhardt G, Ramamoorthy S, Leibach FH, Ganapathy V. Characterization of an ATP-driven H+ pump in human placental brush-border membrane vesicles. The Biochemical Journal. 423-30. PMID 1445200 DOI: 10.1042/Bj2870423  0.141
2014 Ramachandran S, Pathania R, Padia RN, Elangovan S, Coothankandaswamy V, Prasad PD, Ganapathy V, Thangaraju M. Abstract 2461: SLC5A8: A strategic target for advanced metastatic breast cancer Cancer Research. 74: 2461-2461. DOI: 10.1158/1538-7445.Am2014-2461  0.14
1996 Muller U, Brandsch M, Prasad PD, Fei YJ, Ganapathy V, Leibach FH. Inhibition of the H+/peptide cotransporter in the human intestinal cell line Caco-2 by cyclic AMP. Biochemical and Biophysical Research Communications. 218: 461-5. PMID 8561778 DOI: 10.1006/Bbrc.1996.0082  0.14
2007 Dun Y, Thangaraju M, Prasad P, Ganapathy V, Smith SB. Prevention of excitotoxicity in primary retinal ganglion cells by (+)-pentazocine, a sigma receptor-1 specific ligand. Investigative Ophthalmology & Visual Science. 48: 4785-94. PMID 17898305 DOI: 10.1167/Iovs.07-0343  0.139
2001 Ola MS, Moore P, El-Sherbeny A, Roon P, Agarwal N, Sarthy VP, Casellas P, Ganapathy V, Smith SB. Expression pattern of sigma receptor 1 mRNA and protein in mammalian retina. Brain Research. Molecular Brain Research. 95: 86-95. PMID 11687279 DOI: 10.1016/S0169-328X(01)00249-2  0.139
2014 Elangovan S, Pathania R, Ramachandran S, Ananth S, Padia RN, Lan L, Singh N, Martin PM, Hawthorn L, Prasad PD, Ganapathy V, Thangaraju M. The niacin/butyrate receptor GPR109A suppresses mammary tumorigenesis by inhibiting cell survival. Cancer Research. 74: 1166-78. PMID 24371223 DOI: 10.1158/0008-5472.Can-13-1451  0.136
2006 Jiang G, Mysona B, Dun Y, Gnana-Prakasam JP, Pabla N, Li W, Dong Z, Ganapathy V, Smith SB. Expression, subcellular localization, and regulation of sigma receptor in retinal muller cells. Investigative Ophthalmology & Visual Science. 47: 5576-82. PMID 17122151 DOI: 10.1167/Iovs.06-0608  0.136
2009 Thangaraju M, Karunakaran SK, Itagaki S, Gopal E, Elangovan S, Prasad PD, Ganapathy V. Transport by SLC5A8 with subsequent inhibition of histone deacetylase 1 (HDAC1) and HDAC3 underlies the antitumor activity of 3-bromopyruvate. Cancer. 115: 4655-66. PMID 19637353 DOI: 10.1002/Cncr.24532  0.135
2003 Dey S, Patel J, Anand BS, Jain-Vakkalagadda B, Kaliki P, Pal D, Ganapathy V, Mitra AK. Molecular evidence and functional expression of P-glycoprotein (MDR1) in human and rabbit cornea and corneal epithelial cell lines. Investigative Ophthalmology & Visual Science. 44: 2909-18. PMID 12824231 DOI: 10.1167/Iovs.02-1142  0.134
2007 Seki A, Miyauchi S, Hayashi S, Kikukawa T, Kubo M, Demura M, Ganapathy V, Kamo N. Heterologous expression of Pharaonis halorhodopsin in Xenopus laevis oocytes and electrophysiological characterization of its light-driven Cl- pump activity. Biophysical Journal. 92: 2559-69. PMID 17208978 DOI: 10.1529/Biophysj.106.093153  0.134
2013 Shekhawat PS, Sonne S, Carter AL, Matern D, Ganapathy V. Enzymes involved in L-carnitine biosynthesis are expressed by small intestinal enterocytes in mice: implications for gut health. Journal of Crohn's & Colitis. 7: e197-205. PMID 22999781 DOI: 10.1016/J.Crohns.2012.08.011  0.134
2019 Kou L, Sun R, Xiao S, Zheng Y, Chen Z, Cai A, Zheng H, Yao Q, Ganapathy V, Chen R. An Ambidextrous Approach to Disrupt Redox Balance in Tumor Cell with Increased ROS Production and Decreased GSH Synthesis for Cancer Therapy. Acs Applied Materials & Interfaces. PMID 31276364 DOI: 10.1021/Acsami.9B09784  0.133
2004 Chen Z, Huang W, Srinivas SR, Jones CR, Ganapathy V, Prasad PD. Serine racemase and D-serine transport in human placenta and evidence for a transplacental gradient for D-serine in humans. Journal of the Society For Gynecologic Investigation. 11: 294-303. PMID 15219883 DOI: 10.1016/J.Jsgi.2004.02.003  0.133
2015 Ganapathy V, Gurav A, Gnanaprakasam JP, Babu E, Bhutia YD, Webb CR, Grisham MB. Abstract 1557: The iron-overload genetic disease hemochromatosis potentiates colonic inflammation and colon carcinogenesis Cancer Research. 75: 1557-1557. DOI: 10.1158/1538-7445.Am2015-1557  0.132
1994 Prasad PD, Ramamoorthy S, Moe AJ, Smith CH, Leibach FH, Ganapathy V. Selective expression of the high-affinity isoform of the folate receptor (FR-alpha) in the human placental syncytiotrophoblast and choriocarcinoma cells. Biochimica Et Biophysica Acta. 1223: 71-5. PMID 8061055 DOI: 10.1016/0167-4889(94)90074-4  0.132
2007 Makrides V, Bauer R, Weber W, Wester HJ, Fischer S, Hinz R, Huggel K, Opfermann T, Herzau M, Ganapathy V, Verrey F, Brust P. Preferred transport of O-(2-[18F]fluoroethyl)-D-tyrosine (D-FET) into the porcine brain. Brain Research. 1147: 25-33. PMID 17343835 DOI: 10.1016/J.Brainres.2007.02.008  0.132
1999 Tang NL, Ganapathy V, Wu X, Hui J, Seth P, Yuen PM, Wanders RJ, Fok TF, Hjelm NM. Mutations of OCTN2, an organic cation/carnitine transporter, lead to deficient cellular carnitine uptake in primary carnitine deficiency. Human Molecular Genetics. 8: 655-60. PMID 10072434 DOI: 10.1093/Hmg/8.4.655  0.132
2004 Martin PM, Ola MS, Agarwal N, Ganapathy V, Smith SB. The sigma receptor ligand (+)-pentazocine prevents apoptotic retinal ganglion cell death induced in vitro by homocysteine and glutamate. Brain Research. Molecular Brain Research. 123: 66-75. PMID 15046867 DOI: 10.1016/J.Molbrainres.2003.12.019  0.132
2017 Ogura J, Miyauchi S, Shimono K, Yang S, Gonchigar S, Ganapathy V, Bhutia YD. Carbidopa is an activator of aryl hydrocarbon receptor with potential for cancer therapy. The Biochemical Journal. 474: 3391-3402. PMID 28963435 DOI: 10.1042/Bcj20170583  0.131
2012 Sonne S, Shekhawat PS, Matern D, Ganapathy V, Ignatowicz L. Carnitine deficiency in OCTN2-/- newborn mice leads to a severe gut and immune phenotype with widespread atrophy, apoptosis and a pro-inflammatory response. Plos One. 7: e47729. PMID 23112839 DOI: 10.1371/Journal.Pone.0047729  0.131
2019 Brown T, Ramachandran S, Offermanns S, Ganapathy V. Abstract 4357: The lactate receptor Gpr81 on non-cancer cells promotes an immunosuppressive phenotype in the tumor microenvironment Cancer Research. 79: 4357-4357. DOI: 10.1158/1538-7445.Sabcs18-4357  0.131
2001 Seth P, Ganapathy ME, Conway SJ, Bridges CD, Smith SB, Casellas P, Ganapathy V. Expression pattern of the type 1 sigma receptor in the brain and identity of critical anionic amino acid residues in the ligand-binding domain of the receptor. Biochimica Et Biophysica Acta. 1540: 59-67. PMID 11476895 DOI: 10.1016/S0167-4889(01)00117-3  0.13
2006 Gupta N, Martin PM, Miyauchi S, Ananth S, Herdman AV, Martindale RG, Podolsky R, Ganapathy V. Down-regulation of BCRP/ABCG2 in colorectal and cervical cancer. Biochemical and Biophysical Research Communications. 343: 571-7. PMID 16554028 DOI: 10.1016/J.Bbrc.2006.02.172  0.129
2020 Kou L, Sun R, Xiao S, Cui X, Sun J, Ganapathy V, Yao Q, Chen R. OCTN2-targeted nanoparticles for oral delivery of paclitaxel: differential impact of the polyethylene glycol linker size on drug delivery , , and . Drug Delivery. 27: 170-179. PMID 31913724 DOI: 10.1080/10717544.2019.1710623  0.129
2013 Markand S, Tawfik A, Ha Y, Gnana-Prakasam J, Sonne S, Ganapathy V, Sen N, Xian M, Smith SB. Cystathionine beta synthase expression in mouse retina. Current Eye Research. 38: 597-604. PMID 23470016 DOI: 10.3109/02713683.2013.774024  0.128
2013 Peden AS, Mac P, Fei YJ, Castro C, Jiang G, Murfitt KJ, Miska EA, Griffin JL, Ganapathy V, Jorgensen EM. Betaine acts on a ligand-gated ion channel in the nervous system of the nematode C. elegans. Nature Neuroscience. 16: 1794-801. PMID 24212673 DOI: 10.1038/Nn.3575  0.126
2009 Gnana-Prakasam JP, Zhang M, Martin PM, Atherton SS, Smith SB, Ganapathy V. Expression of the iron-regulatory protein haemojuvelin in retina and its regulation during cytomegalovirus infection. The Biochemical Journal. 419: 533-43. PMID 19191760 DOI: 10.1042/Bj20082240  0.126
1995 Ramamoorthy JD, Ramamoorthy S, Mahesh VB, Leibach FH, Ganapathy V. Cocaine-sensitive sigma-receptor and its interaction with steroid hormones in the human placental syncytiotrophoblast and in choriocarcinoma cells. Endocrinology. 136: 924-32. PMID 7867601 DOI: 10.1210/Endo.136.3.7867601  0.126
2010 Kwon IK, Wang R, Thangaraju M, Shuang H, Liu K, Dashwood R, Dulin N, Ganapathy V, Browning DD. PKG inhibits TCF signaling in colon cancer cells by blocking beta-catenin expression and activating FOXO4. Oncogene. 29: 3423-34. PMID 20348951 DOI: 10.1038/Onc.2010.91  0.125
2004 Gupta N, Miyauchi S, Martindale R, Moore-Martin P, Podolsky R, Ganapathy V. Mitoxantrone Resistance protein (MXR) is down-regulated in colorectal cancer Journal of Surgical Research. 121: 299. DOI: 10.1016/J.Jss.2004.07.107  0.125
1992 Smith CH, Moe AJ, Ganapathy V. Nutrient transport pathways across the epithelium of the placenta. Annual Review of Nutrition. 12: 183-206. PMID 1503803 DOI: 10.1146/Annurev.Nu.12.070192.001151  0.124
2014 Promsote W, Makala L, Li B, Smith SB, Singh N, Ganapathy V, Pace BS, Martin PM. Monomethylfumarate induces γ-globin expression and fetal hemoglobin production in cultured human retinal pigment epithelial (RPE) and erythroid cells, and in intact retina. Investigative Ophthalmology & Visual Science. 55: 5382-93. PMID 24825111 DOI: 10.1167/Iovs.14-14179  0.124
2021 Bridges AE, Ramachandran S, Tamizhmani K, Parwal U, Lester A, Rajpurohit P, Morera DS, Hasanali SL, Arjunan P, Jedeja RN, Patel N, Marin PM, Korkaya H, Singh N, Manicassamy S, ... ... Ganapathy V, et al. RAD51AP1 loss attenuates colorectal cancer stem cell renewal and sensitizes to chemotherapy. Molecular Cancer Research : McR. PMID 34099522 DOI: 10.1158/1541-7786.MCR-20-0780  0.123
2006 Hou Y, Gupta N, Schoenlein P, Wong E, Martindale R, Ganapathy V, Browning D. An anti-tumor role for cGMP-dependent protein kinase. Cancer Letters. 240: 60-8. PMID 16256267 DOI: 10.1016/J.Canlet.2005.08.035  0.123
1995 Yang-Feng TL, Ma YY, Liang R, Prasad PD, Leibach FH, Ganapathy V. Assignment of the human folate transporter gene to chromosome 21q22.3 by somatic cell hybrid analysis and in situ hybridization. Biochemical and Biophysical Research Communications. 210: 874-9. PMID 7763259 DOI: 10.1006/bbrc.1995.1739  0.123
2007 Schoenlein PV, Hou M, Samaddar JS, Gaddy VT, Thangaraju M, Lewis J, Johnson M, Ganapathy V, Kallab A, Barrett JT. Downregulation of retinoblastoma protein is involved in the enhanced cytotoxicity of 4-hydroxytamoxifen plus mifepristone combination therapy versus antiestrogen monotherapy of human breast cancer. International Journal of Oncology. 31: 643-55. PMID 17671693 DOI: 10.3892/Ijo.31.3.643  0.123
2007 Yang D, Thangaraju M, Browning DD, Dong Z, Korchin B, Lev DC, Ganapathy V, Liu K. IFN regulatory factor 8 mediates apoptosis in nonhemopoietic tumor cells via regulation of Fas expression. Journal of Immunology (Baltimore, Md. : 1950). 179: 4775-82. PMID 17878376 DOI: 10.4049/Jimmunol.179.7.4775  0.122
2016 Irving BA, Wood GC, Bennotti PN, Babu E, Deshpande A, Lent MR, Petrick A, Gabrielsen J, Strodel W, Gerhard GS, Still CD, Ganapathy V, Rolston DD. Nutrient Transporter Expression in the Jejunum in Relation to Body Mass Index in Patients Undergoing Bariatric Surgery. Nutrients. 8. PMID 27801863 DOI: 10.3390/Nu8110683  0.121
2018 Ranganathan P, Shanmugam A, Swafford D, Suryawanshi A, Bhattacharjee P, Hussein MS, Koni PA, Prasad PD, Kurago ZB, Thangaraju M, Ganapathy V, Manicassamy S. GPR81, a Cell-Surface Receptor for Lactate, Regulates Intestinal Homeostasis and Protects Mice from Experimental Colitis. Journal of Immunology (Baltimore, Md. : 1950). PMID 29386257 DOI: 10.4049/Jimmunol.1700604  0.121
2012 Prakasam JPG, Pathania R, Veeranan-Karmegam R, Ramachandran S, Thangaraju M, Ganapathy V. Abstract 3599: Expression and function of HFE in mammary gland iron homeostasis and its relevance to breast cancer Cancer Research. 72: 3599-3599. DOI: 10.1158/1538-7445.Am2012-3599  0.12
2011 Li HM, Zhang M, Xu ST, Li DZ, Zhu LY, Peng SW, Chen GQ, Martin PM, Ganapathy V, Wei CJ. Nicotinic acid inhibits glucose-stimulated insulin secretion via the G protein-coupled receptor PUMA-G in murine islet β cells. Pancreas. 40: 615-21. PMID 21441844 DOI: 10.1097/Mpa.0B013E31820B4B23  0.12
2017 Ristic B, Bhutia YD, Ganapathy V. Cell-surface G-protein-coupled receptors for tumor-associated metabolites: A direct link to mitochondrial dysfunction in cancer. Biochimica Et Biophysica Acta. PMID 28512002 DOI: 10.1016/J.Bbcan.2017.05.003  0.12
2014 Takhar S, Manning M, Eason A, Dix M, Periyasamy-Thandavan S, Padi R, Bieberich E, Hill W, Browning D, Ganapathy V, Thangaraju M, Schoenlein PV. Abstract B50: MEK inhibitors mount a two-pronged attack to kill estrogen receptor positive (ER+) breast cancer cells undergoing hormonal therapy: Attenuated autophagy and induction of apoptosis Molecular Cancer Research. 12. DOI: 10.1158/1557-3125.Rasonc14-B50  0.12
2011 Elangovan S, Ramachandran S, Prasad PD, Ganapathy V, Thangaraju M. Abstract 4032: SIRT1 modulates E2/ERα-associated oncogenic signaling in human breast cancer Cancer Research. 71: 4032-4032. DOI: 10.1158/1538-7445.Am2011-4032  0.12
2016 Pathania R, Kolhe RB, Ramachandran S, Mariappan G, Thakur P, Prasad PD, Ganapathy V, Thangaraju M. Abstract 3325: Combination of DNMT and HDAC inhibitors reprogram cancer stem cell signaling to overcome drug resistance Cancer Research. 76: 3325-3325. DOI: 10.1158/1538-7445.Am2016-3325  0.119
1990 Kulanthaivel P, Leibach FH, Mahesh VB, Cragoe EJ, Ganapathy V. The Na(+)-H+ exchanger of the placental brush-border membrane is pharmacologically distinct from that of the renal brush-border membrane. Journal of Biological Chemistry. 265: 1249-1252. DOI: 10.1016/s0021-9258(19)40005-7  0.118
2014 Singh N, Gurav A, Sivaprakasam S, Brady E, Padia R, Shi H, Thangaraju M, Prasad PD, Manicassamy S, Munn DH, Lee JR, Offermanns S, Ganapathy V. Activation of Gpr109a, receptor for niacin and the commensal metabolite butyrate, suppresses colonic inflammation and carcinogenesis. Immunity. 40: 128-39. PMID 24412617 DOI: 10.1016/J.Immuni.2013.12.007  0.118
1998 Seth P, Fei YJ, Li HW, Huang W, Leibach FH, Ganapathy V. Cloning and functional characterization of a sigma receptor from rat brain. Journal of Neurochemistry. 70: 922-31. PMID 9489711 DOI: 10.1046/J.1471-4159.1998.70030922.X  0.117
1996 Ganapathy V, Roque A, Prasad P, Bhatia J, Leibach F. Sodium-dependent high-affinity binding of carnitine to human placental brush border membranes Placenta. 17: A25. DOI: 10.1016/s0143-4004(96)90160-5  0.117
2014 Ramachandran I, Ganapathy V, Gillies E, Fonseca I, Sureban SM, Houchen CW, Reis A, Queimado L. Wnt inhibitory factor 1 suppresses cancer stemness and induces cellular senescence. Cell Death & Disease. 5: e1246. PMID 24853424 DOI: 10.1038/cddis.2014.219  0.116
2016 Pathania R, Ramachandran S, Mariappan G, Thakur P, Shi H, Choi JH, Manicassamy S, Kolhe R, Prasad PD, Sharma S, Lokeshwar BL, Ganapathy V, Thangaraju M. Combined inhibition of DNMT and HDAC blocks the tumorigenicity of cancer stem-like cells and attenuates mammary tumor growth. Cancer Research. PMID 27197203 DOI: 10.1158/0008-5472.Can-15-2249  0.115
2015 Pathania R, Ramachandran S, Prasad P, Ganapathy V, Thangaraju M. Abstract LB-142: Functional role of DNA methyltransferase1 (DNMT1) in regulation of mammary stem/progenitor and cancer stem cells Cancer Research. 75. DOI: 10.1158/1538-7445.Am2015-Lb-142  0.115
2015 Pathania R, Ramachandran S, Elangovan S, Padia R, Yang P, Cinghu S, Veeranan-Karmegam R, Arjunan P, Gnana-Prakasam JP, Sadanand F, Pei L, Chang CS, Choi JH, Shi H, Manicassamy S, ... ... Ganapathy V, et al. DNMT1 is essential for mammary and cancer stem cell maintenance and tumorigenesis. Nature Communications. 6: 6910. PMID 25908435 DOI: 10.1038/Ncomms7910  0.115
2020 Sivaprakasam S, Ristic B, Mudaliar N, Hamood A, Colmer-Hamood J, Wachtel M, Nevels AG, Kottapalli KR, Ganapathy V. Hereditary Hemochromatosis Promotes Colitis and Colon Cancer and Causes Bacterial Dysbiosis in Mice. The Biochemical Journal. PMID 32955078 DOI: 10.1042/Bcj20200392  0.115
2013 Sonne SR, Bhalla VK, Barman SA, White RE, Zhu S, Newman TM, Prasad PD, Smith SB, Offermanns S, Ganapathy V. Hyperhomocysteinemia is detrimental to pregnancy in mice and is associated with preterm birth. Biochimica Et Biophysica Acta. 1832: 1149-58. PMID 23579073 DOI: 10.1016/J.Bbadis.2013.04.006  0.115
2016 Promsote W, Powell FL, Veean S, Thounaojam M, Markand S, Saul A, Gutsaeva D, Bartoli M, Smith SB, Ganapathy V, Martin P. Oral monomethylfumarate therapy ameliorates retinopathy in a humanized mouse model of sickle cell disease. Antioxidants & Redox Signaling. PMID 27393735 DOI: 10.1089/Ars.2016.6638  0.114
2013 Elangovan S, Pathania R, Ramachandran S, Ananth S, Padia RN, Srinivas SR, Babu E, Hawthorn L, Schoenlein PV, Boettger T, Smith SB, Prasad PD, Ganapathy V, Thangaraju M. Molecular mechanism of SLC5A8 inactivation in breast cancer. Molecular and Cellular Biology. 33: 3920-35. PMID 23918800 DOI: 10.1128/Mcb.01702-12  0.113
1994 Prasad P, Leibach F, Mahesh V, Ganapathy V. Human placenta as a target organ for cocaine action: Interaction of cocaine with the placental serotonin transporter International Journal of Gynecology & Obstetrics. 47: 316-317. DOI: 10.1016/0020-7292(94)90591-6  0.113
1993 Pillion DJ, Grizzle WE, Yang M, Meezan E, Stockard CR, Ganapathy V, Leibach FH, Myers RB, Haskell JF. Expression of IGF-II/Man-6-P receptors on rat, rabbit, and human colon epithelial cells. The American Journal of Physiology. 264: R1101-10. PMID 8322962 DOI: 10.1152/Ajpregu.1993.264.6.R1101  0.113
2008 Dun Y, Duplantier J, Roon P, Martin PM, Ganapathy V, Smith SB. Serine racemase expression and D-serine content are developmentally regulated in neuronal ganglion cells of the retina. Journal of Neurochemistry. 104: 970-8. PMID 17976164 DOI: 10.1111/J.1471-4159.2007.05015.X  0.112
2014 Ha Y, Shanmugam AK, Markand S, Zorrilla E, Ganapathy V, Smith SB. Sigma receptor 1 modulates ER stress and Bcl2 in murine retina. Cell and Tissue Research. 356: 15-27. PMID 24469320 DOI: 10.1007/S00441-013-1774-8  0.112
2020 Brown TP, Bhattacharjee P, Ramachandran S, Sivaprakasam S, Ristic B, Sikder MOF, Ganapathy V. The lactate receptor GPR81 promotes breast cancer growth via a paracrine mechanism involving antigen-presenting cells in the tumor microenvironment. Oncogene. PMID 32071396 DOI: 10.1038/S41388-020-1216-5  0.112
2017 Sivaprakasam S, Bhutia YD, Ramachandran S, Ganapathy V. Cell-Surface and Nuclear Receptors in the Colon as Targets for Bacterial Metabolites and Its Relevance to Colon Health. Nutrients. 9. PMID 28796169 DOI: 10.3390/Nu9080856  0.111
2007 Baisden B, Sonne S, Joshi RM, Ganapathy V, Shekhawat PS. Antenatal dexamethasone treatment leads to changes in gene expression in a murine late placenta. Placenta. 28: 1082-90. PMID 17559929 DOI: 10.1016/J.Placenta.2007.04.002  0.111
2020 Bridges AE, Ramachandran S, Pathania R, Parwal U, Lester A, Rajpurohit P, Morera DS, Patel N, Singh N, Korkaya H, Manicassamy S, Prasad PD, Lokeshwar VB, Lokeshwar BL, Ganapathy V, et al. RAD51AP1 deficiency reduces tumor growth by targeting stem cell self-renewal. Cancer Research. PMID 32665355 DOI: 10.1158/0008-5472.Can-19-3713  0.111
2019 Sivaprakasam S, Ganapathy PK, Sikder MOF, Elmassry M, Ramachandran S, Kottapalli KR, Ganapathy V. Deficiency of Dietary Fiber in -Null Mice Promotes Bacterial Dysbiosis and Alters Colonic Epithelial Transcriptome towards Proinflammatory Milieu. Canadian Journal of Gastroenterology & Hepatology. 2019: 2543082. PMID 31976310 DOI: 10.1155/2019/2543082  0.111
2001 Moore P, El-sherbeny A, Roon P, Schoenlein PV, Ganapathy V, Smith SB. Apoptotic cell death in the mouse retinal ganglion cell layer is induced in vivo by the excitatory amino acid homocysteine. Experimental Eye Research. 73: 45-57. PMID 11428862 DOI: 10.1006/Exer.2001.1009  0.11
2002 Rausch JL, Gillespie CF, Fei Y, Hobby HM, Stoming T, Ganapathy V, Leibach FH. Antidepressant effects on kinase gene expression patterns in rat brain. Neuroscience Letters. 334: 91-4. PMID 12435479 DOI: 10.1016/S0304-3940(02)01106-0  0.108
2010 Periyasamy-Thandavan S, Jackson WH, Samaddar JS, Erickson B, Barrett JR, Raney L, Gopal E, Ganapathy V, Hill WD, Bhalla KN, Schoenlein PV. Bortezomib blocks the catabolic process of autophagy via a cathepsin-dependent mechanism, affects endoplasmic reticulum stress and induces caspase-dependent cell death in antiestrogen-sensitive and resistant ER+ breast cancer cells. Autophagy. 6: 19-35. PMID 20110775 DOI: 10.4161/Auto.6.1.10323  0.108
2020 Bhutia YD, Ogura J, Grippo PJ, Torres C, Sato T, Wachtel M, Ramachandran S, Babu E, Sivaprakasam S, Rajasekaran D, Schniers B, On N, Smoot L, Thangaraju M, Gnana-Prakasam JP, ... Ganapathy V, et al. Chronic exposure to excess iron promotes EMT and cancer via p53 loss in pancreatic cancer. Asian Journal of Pharmaceutical Sciences. 15: 237-251. PMID 32373202 DOI: 10.1016/J.Ajps.2020.02.003  0.108
1985 Ganapathy V, Pashley SJ, Roesel RA, Pashley DH, Leibach FH. Inhibition of rat and human prolidases by captopril. Biochemical Pharmacology. 34: 1287-91. PMID 3888225 DOI: 10.1016/0006-2952(85)90507-6  0.107
2011 Vasudevan M, Ganapathy V. Designing large package boilers Power. 155.  0.106
2015 Shanmugam AK, Mysona BA, Wang J, Zhao J, Tawfik A, Sanders A, Markand S, Zorrilla E, Ganapathy V, Bollinger KE, Smith SB. Progesterone Receptor Membrane Component 1 (PGRMC1) Expression in Murine Retina. Current Eye Research. 1-8. PMID 26642738 DOI: 10.3109/02713683.2015.1085579  0.106
2019 Sadeghzadeh M, Moldovan RP, Fischer S, Wenzel B, Ludwig FA, Teodoro R, Deuther-Conrad W, Jonnalagadda S, Jonnalagadda SK, Gudelis E, Šačkus A, Higuchi K, Ganapathy V, Mereddy VR, Drewes LR, et al. Development and radiosynthesis of the first F-labeled inhibitor of monocarboxylate transporters (MCTs). Journal of Labelled Compounds & Radiopharmaceuticals. PMID 31017677 DOI: 10.1002/Jlcr.3739  0.106
2013 Tawfik A, Al-Shabrawey M, Roon P, Sonne S, Covar JA, Matragoon S, Ganapathy PS, Atherton SS, El-Remessy A, Ganapathy V, Smith SB. Alterations of retinal vasculature in cystathionine-Beta-synthase mutant mice, a model of hyperhomocysteinemia. Investigative Ophthalmology & Visual Science. 54: 939-49. PMID 23307965 DOI: 10.1167/Iovs.12-10536  0.105
2018 Bhatt B, Zeng P, Zhu H, Sivaprakasam S, Li S, Xiao H, Dong L, Shiao P, Kolhe R, Patel N, Li H, Levy-Bercowski D, Ganapathy V, Singh N. Gpr109a Limits Microbiota-Induced IL-23 Production To Constrain ILC3-Mediated Colonic Inflammation. Journal of Immunology (Baltimore, Md. : 1950). PMID 29514953 DOI: 10.4049/Jimmunol.1701625  0.105
1998 Prasad PD, Li HW, Fei YJ, Ganapathy ME, Fujita T, Plumley LH, Yang-Feng TL, Leibach FH, Ganapathy V. Exon-intron structure, analysis of promoter region, and chromosomal localization of the human type 1 sigma receptor gene. Journal of Neurochemistry. 70: 443-51. PMID 9453537 DOI: 10.1046/J.1471-4159.1998.70020443.X  0.104
2011 Gnana-Prakasam JP, Ananth S, Prasad PD, Zhang M, Atherton SS, Martin PM, Smith SB, Ganapathy V. Expression and iron-dependent regulation of succinate receptor GPR91 in retinal pigment epithelium. Investigative Ophthalmology & Visual Science. 52: 3751-8. PMID 21357408 DOI: 10.1167/Iovs.10-6722  0.104
2011 Elangovan S, Ramachandran S, Venkatesan N, Ananth S, Gnana-Prakasam JP, Martin PM, Browning DD, Schoenlein PV, Prasad PD, Ganapathy V, Thangaraju M. SIRT1 is essential for oncogenic signaling by estrogen/estrogen receptor α in breast cancer. Cancer Research. 71: 6654-64. PMID 21920899 DOI: 10.1158/0008-5472.Can-11-1446  0.103
2002 Ola MS, Moore P, Maddox D, El-Sherbeny A, Huang W, Roon P, Agarwal N, Ganapathy V, Smith SB. Analysis of sigma receptor (sigmaR1) expression in retinal ganglion cells cultured under hyperglycemic conditions and in diabetic mice. Brain Research. Molecular Brain Research. 107: 97-107. PMID 12425939 DOI: 10.1016/S0169-328X(02)00444-8  0.103
2011 Ha Y, Saul A, Tawfik A, Williams C, Bollinger K, Smith R, Tachikawa M, Zorrilla E, Ganapathy V, Smith SB. Late-onset inner retinal dysfunction in mice lacking sigma receptor 1 (σR1). Investigative Ophthalmology & Visual Science. 52: 7749-60. PMID 21862648 DOI: 10.1167/Iovs.11-8169  0.102
2021 Sivaprakasam S, Sikder MOF, Ramalingam L, Kaur G, Dufour JM, Moustaid-Moussa N, Wachtel MS, Ganapathy V. SLC6A14 deficiency is linked to obesity, fatty liver, and metabolic syndrome but only under conditions of a high-fat diet. Biochimica Et Biophysica Acta. Molecular Basis of Disease. 166087. PMID 33513428 DOI: 10.1016/j.bbadis.2021.166087  0.101
2001 Bridges CC, El-Sherbeny A, Roon P, Ola MS, Kekuda R, Ganapathy V, Camero RS, Cameron PL, Smith SB. A comparison of caveolae and caveolin-1 to folate receptor alpha in retina and retinal pigment epithelium. The Histochemical Journal. 33: 149-58. PMID 11508338 DOI: 10.1023/A:1017991925821  0.101
2007 Yang D, Thangaraju M, Greeneltch K, Browning DD, Schoenlein PV, Tamura T, Ozato K, Ganapathy V, Abrams SI, Liu K. Repression of IFN regulatory factor 8 by DNA methylation is a molecular determinant of apoptotic resistance and metastatic phenotype in metastatic tumor cells. Cancer Research. 67: 3301-9. PMID 17409439 DOI: 10.1158/0008-5472.Can-06-4068  0.101
2006 Martin PM, Gnana-Prakasam JP, Roon P, Smith RG, Smith SB, Ganapathy V. Expression and polarized localization of the hemochromatosis gene product HFE in retinal pigment epithelium. Investigative Ophthalmology & Visual Science. 47: 4238-44. PMID 17003411 DOI: 10.1167/Iovs.06-0026  0.101
2009 Cresci G, Thangaraju M, Liu K, Mellinger JD, Ganapathy V. 624 Influence of Colonic Bacteria On the Expression of Host Intestinal Tract Genes Which Regulate Water and Electrolyte Absorption Gastroenterology. 136: A-874. DOI: 10.1016/S0016-5085(09)64038-5  0.1
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