Youla Tsantrizos, Ph.D.
Affiliations: | 1997- | Chemistry | McGill University, Montreal, QC, Canada |
Area:
CrystallographyWebsite:
http://tsantrizos-group.mcgill.ca/tsantrizos.htmlGoogle:
"Youla Tsantrizos"Bio:
2012 - Queen Elizabeth II Diamond Jubilee Medal "for services to Canada"
Cross-listing: Chemistry Tree
Parents
Sign in to add mentor| George Just | grad student | 1977-1979 | McGill (Chemistry Tree) |
| Kelvin K. Ogilvie | grad student | 1987-1990 | McGill (Chemistry Tree) |
| David E. Cane | post-doc | 1990-1991 | Brown (Chemistry Tree) |
Children
Sign in to add trainee| Xian-Shu Yang | grad student | 2000 | McGill (Chemistry Tree) |
| Lee D. Fader | grad student | 2002 | McGill (Chemistry Tree) |
| J. De Schutter | grad student | 2013 | McGill (Chemistry Tree) |
| Yih-Shyan Lin | grad student | 2014 | McGill (Chemistry Tree) |
| Warren Chew | post-doc | 1996 | McGill (Chemistry Tree) |
| John Mancuso | post-doc | 2009-2010 | McGill (Chemistry Tree) |
| Olivier Leogane | post-doc | 2011-2012 | McGill (Chemistry Tree) |
BETA: Related publications
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Publications
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| Lee HF, Lacbay CM, Boutin R, et al. (2022) Synthesis and Evaluation of Structurally Diverse C-2-Substituted Thienopyrimidine-Based Inhibitors of the Human Geranylgeranyl Pyrophosphate Synthase. Journal of Medicinal Chemistry |
| Park J, Rodionov D, De Schutter JW, et al. (2017) Crystallographic and thermodynamic characterization of phenylaminopyridine bisphosphonates binding to human farnesyl pyrophosphate synthase. Plos One. 12: e0186447 |
| Fader LD, Bailey M, Beaulieu E, et al. (2016) Aligning Potency and Pharmacokinetic Properties for Pyridine-Based NCINIs. Acs Medicinal Chemistry Letters. 7: 797-801 |
| Jansen G, Golizeh M, Martel-Lorion C, et al. (2016) A covalent cysteine-targeting kinase inhibitor of Ire1 permits allosteric control of endoribonuclease activity. Chembiochem : a European Journal of Chemical Biology |
| Fandrick KR, Li W, Zhang Y, et al. (2015) Concise and Practical Asymmetric Synthesis of a Challenging Atropisomeric HIV Integrase Inhibitor. Angewandte Chemie (International Ed. in English). 54: 7144-8 |
| Gritzalis D, Park J, Chiu W, et al. (2015) Probing the molecular and structural elements of ligands binding to the active site versus an allosteric pocket of the human farnesyl pyrophosphate synthase. Bioorganic & Medicinal Chemistry Letters. 25: 1117-23 |
| Lacbay CM, Mancuso J, Lin YS, et al. (2014) Modular assembly of purine-like bisphosphonates as inhibitors of HIV-1 reverse transcriptase. Journal of Medicinal Chemistry. 57: 7435-49 |
| Fader LD, Carson R, Morin S, et al. (2014) Minimizing the Contribution of Enterohepatic Recirculation to Clearance in Rat for the NCINI Class of Inhibitors of HIV. Acs Medicinal Chemistry Letters. 5: 711-6 |
| De Schutter JW, Park J, Leung CY, et al. (2014) Multistage screening reveals chameleon ligands of the human farnesyl pyrophosphate synthase: implications to drug discovery for neurodegenerative diseases. Journal of Medicinal Chemistry. 57: 5764-76 |
| Fader LD, Malenfant E, Parisien M, et al. (2014) Discovery of BI 224436, a Noncatalytic Site Integrase Inhibitor (NCINI) of HIV-1. Acs Medicinal Chemistry Letters. 5: 422-7 |