Parents
Sign in to add mentor| Joseph Zaccai | grad student | 2000 | Grenoble 1 | |
| (Etudes des relations structure-fonction, du repliement et de l'evolution au sein de la super-famille des malates et lactates deshydrogenases) | ||||
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Publications
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| Coquille S, Pereira CS, Roche J, et al. (2025) Allostery and Evolution: A Molecular Journey Through the Structural and Dynamical Landscape of an Enzyme Super Family. Molecular Biology and Evolution. 42 |
| Madern D, Halgand F, Houée-Levin C, et al. (2024) The Characterization of Ancient Methanococcales Malate Dehydrogenases Reveals That Strong Thermal Stability Prevents Unfolding Under Intense γ-Irradiation. Molecular Biology and Evolution. 41 |
| Bertrand Q, Coquille S, Iorio A, et al. (2023) Biochemical, structural and dynamical characterizations of the lactate dehydrogenase from Selenomonas ruminantium provide information about an intermediate evolutionary step prior to complete allosteric regulation acquisition in the super family of lactate and malate dehydrogenases. Journal of Structural Biology. 215: 108039 |
| Robin AY, Brochier-Armanet C, Bertrand Q, et al. (2023) Deciphering Evolutionary Trajectories of Lactate Dehydrogenases Provides New Insights into Allostery. Molecular Biology and Evolution. 40 |
| Iorio A, Brochier-Armanet C, Mas C, et al. (2022) Protein Conformational Space at the Edge of Allostery: Turning a Non-allosteric Malate Dehydrogenase into an "Allosterized" Enzyme using Evolution Guided Punctual Mutations. Molecular Biology and Evolution |
| Iorio A, Roche J, Engilberge S, et al. (2021) Biochemical, structural and dynamical studies reveal strong differences in the thermal-dependent allosteric behavior of two extremophilic lactate dehydrogenases. Journal of Structural Biology. 107769 |
| Blanquart S, Groussin M, Le Roy A, et al. (2021) Resurrection of Ancestral Malate Dehydrogenases Reveals the Evolutionary History of Halobacterial Proteins : Deciphering Gene Trajectories and Changes in Biochemical Properties. Molecular Biology and Evolution |
| Timr S, Madern D, Sterpone F. (2020) Protein thermal stability. Progress in Molecular Biology and Translational Science. 170: 239-272 |
| Halgand F, Houée-Lévin C, Weik M, et al. (2020) Remote oxidative modifications induced by oxygen free radicals modify T/R allosteric equilibrium of a hyperthermophilic lactate dehydrogenase. Journal of Structural Biology. 107478 |
| Katava M, Marchi M, Madern D, et al. (2020) Temperature Unmasks Allosteric Propensity in a Thermophilic Malate Dehydrogenase via Dewetting and Collapse. The Journal of Physical Chemistry. B |