Patrick M. Loerch, Ph.D.

Harvard University, Cambridge, MA, United States

stem cells, gene regulation

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Armour CD, Castle JC, Chen R, et al. (2009) Digital transcriptome profiling using selective hexamer priming for cDNA synthesis. Nature Methods. 6: 647-9
Oberdoerffer P, Michan S, McVay M, et al. (2008) SIRT1 redistribution on chromatin promotes genomic stability but alters gene expression during aging. Cell. 135: 907-18
Loerch PM, Lu T, Dakin KA, et al. (2008) Evolution of the aging brain transcriptome and synaptic regulation. Plos One. 3: e3329
Johnson JM, Castle J, Garrett-Engele P, et al. (2003) Genome-wide survey of human alternative pre-mRNA splicing with exon junction microarrays. Science (New York, N.Y.). 302: 2141-4
Castle J, Garrett-Engele P, Armour CD, et al. (2003) Optimization of oligonucleotide arrays and RNA amplification protocols for analysis of transcript structure and alternative splicing. Genome Biology. 4: R66
Shoemaker DD, Schadt EE, Armour CD, et al. (2001) Experimental annotation of the human genome using microarray technology. Nature. 409: 922-7