☰

Beatrice Mintz, PhD

Affiliations: 
Cancer Biology Fox Chase Cancer Center 
Area:
Melanoma Development, Progression, and Metastasis in Transgenic Mouse Models
Website:
https://www.foxchase.org/beatrice-mintz
Google:
"Beatrice Mintz"
Bio:

http://www.jstor.org/stable/30151968
http://www.casinapioiv.va/content/accademia/en/academicians/ordinary/mintz.html
Navis, Adam R., Beatrice Mintz (1921- ). Embryo Project Encyclopedia (2009-01-21). ISSN: 1940-5030 http://embryo.asu.edu/handle/10776/1959.
Mintz is a pioneer of genetic engineering techniques, and was among the first scientists to generate both chimeric and transgenic mammals
She graduated magna cum laude from Hunter College in 1941 and began graduate studies at New York University. She later transferred to the University of Iowa where she received a Master's degree in 1944 and a Ph.D in 1946

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Parents

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Emil Witschi grad student 1946 University of Iowa
 (Effects of testosterone propionate on sex development in female Ambystoma larvae)

Children

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Blanche Capel grad student Fox Chase Cancer Center (GenetiTree)
Lionel Larue post-doc Fox Chase Cancer Center
Erwin F. Wagner post-doc Fox Chase Cancer Center
John D. Gearhart post-doc 1970-1972 Fox Chase Cancer Center (Neurotree)
Rudolf Jaenisch post-doc 1974 Fox Chase Cancer Center
Michael Karin post-doc 1980 (Neurotree)

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Publications

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Mintz B. (2010) Experimental Study of the Developing Mammalian Egg: Removal of the Zona Pellucida. Science (New York, N.Y.). 138: 594-5
Blelloch RH, Hochedlinger K, Yamada Y, et al. (2004) Nuclear cloning of embryonal carcinoma cells. Proceedings of the National Academy of Sciences of the United States of America. 101: 13985-90
Sai T, Milling SW, Mintz B. (2002) Freezing and thawing of bone marrow-derived murine dendritic cells with subsequent retention of immunophenotype and of antigen processing and presentation characteristics. Journal of Immunological Methods. 264: 153-62
Kelsall SR, Le Fur N, Mintz B. (1997) Qualitative and quantitative catalog of tyrosinase alternative transcripts in normal murine skin melanocytes as a basis for detecting melanoma-specific changes. Biochemical and Biophysical Research Communications. 236: 173-7
MINTZ B. (1996) GENETIC MOSAICISM IN ADULT MICE OF QUADRIPARENTAL LINEAGE. Science (New York, N.Y.). 148: 1232-3
Mintz B, Silvers WK, Klein-Szanto AJ. (1993) Histopathogenesis of malignant skin melanoma induced in genetically susceptible transgenic mice. Proceedings of the National Academy of Sciences of the United States of America. 90: 8822-6
Mintz B, Silvers WK. (1993) Transgenic mouse model of malignant skin melanoma. Proceedings of the National Academy of Sciences of the United States of America. 90: 8817-21
Larue L, Dougherty N, Bradl M, et al. (1993) Melanocyte culture lines from Tyr-SV40E transgenic mice: models for the molecular genetic evolution of malignant melanoma. Oncogene. 8: 523-31
Mintz B, Klein-Szanto AJ. (1992) Malignancy of eye melanomas originating in the retinal pigment epithelium of transgenic mice after genetic ablation of choroidal melanocytes. Proceedings of the National Academy of Sciences of the United States of America. 89: 11421-5
Larue L, Dougherty N, Porter S, et al. (1992) Spontaneous malignant transformation of melanocytes explanted from Wf/Wf mice with a Kit kinase-domain mutation. Proceedings of the National Academy of Sciences of the United States of America. 89: 7816-20
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