Xiaowan Zheng, Ph.D.
Affiliations: | 2010 | Pharmaceutical Sciences | University of Maryland School of Medicine, Baltimore, MD, United States |
Area:
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"Xiaowan Zheng"Parents
Sign in to add mentorJames E. Polli | grad student | 2010 | University of Maryland Medical School | |
(Inhibition and substrate requirements of human apical sodium-dependent bile acid transporter (ASBT) and its potential as a prodrug target.) |
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Publications
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Zheng X, Pan Y, Acharya C, et al. (2010) Structural requirements of the ASBT by 3D-QSAR analysis using aminopyridine conjugates of chenodeoxycholic acid. Bioconjugate Chemistry. 21: 2038-48 |
Zheng X, Polli JE. (2010) Synthesis and in vitro evaluation of potential sustained release prodrugs via targeting ASBT. International Journal of Pharmaceutics. 396: 111-8 |
Zheng X, Diao L, Ekins S, et al. (2010) Why we should be vigilant: drug cytotoxicity observed with in vitro transporter inhibition studies. Biochemical Pharmacology. 80: 1087-92 |
Zheng X, Polli J. (2010) Identification of inhibitor concentrations to efficiently screen and measure inhibition Ki values against solute carrier transporters. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 41: 43-52 |
Zheng X, Ekins S, Raufman JP, et al. (2009) Computational models for drug inhibition of the human apical sodium-dependent bile acid transporter. Molecular Pharmaceutics. 6: 1591-603 |
Rais R, Gonzalez PM, Zheng X, et al. (2008) Method to screen substrates of apical sodium-dependent bile acid transporter. The Aaps Journal. 10: 596-605 |