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Theodore W. Randolph

Affiliations: 
1993- Chemical Engineering University of Colorado, Boulder, Boulder, CO, United States 
Area:
Pharmaceutical Chemistry, Physical Chemistry
Website:
https://www.colorado.edu/chbe/theodore-w-randolph
Google:
"Theodore Randolph"
Bio:

https://www.colorado.edu/chbe/sites/default/files/attached-files/randolph_theodore_cv2019.pdf

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Parents

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Harvey W. Blanch grad student 1983-1987 UC Berkeley (Chemistry Tree)
 (Enzyme-Catalyzed Reactions in Supercritical Fluids.)
John M. Prausnitz grad student 1983-1987 UC Berkeley (Chemistry Tree)
Urs von Stockar post-doc 1987-1989 EPFL

Children

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James A. Searles grad student 2000 CU Boulder
Jonathan N. Webb grad student 2000 CU Boulder
Roberto A. DePaz grad student 2001 CU Boulder
Richard J. St. John grad student 2001 CU Boulder
Serena D. Webb grad student 2001 CU Boulder
Danielle L. Biggs grad student 2003 CU Boulder
Eva Y. Chi grad student 2004 CU Boulder
Daniel J. Jarmer grad student 2004 CU Boulder
Matthew B. Seefeldt grad student 2004 CU Boulder
Michael R. Stoner grad student 2004 CU Boulder
John R. Alford grad student 2007 CU Boulder
Amber L. Clausi grad student 2007 CU Boulder
John P. Gabrielson grad student 2007 CU Boulder
Jared S. Bee grad student 2009 CU Boulder
Ryan L. Crisman grad student 2009 CU Boulder
Amber H. Fradkin grad student 2009 CU Boulder
Branden A. Salinas grad student 2009 CU Boulder
D. Brett Ludwig grad student 2010 CU Boulder
Amanda A. Cordes grad student 2011 CU Boulder
Maliheh Shomali grad student 2013 CU Boulder
Kimberly J. Hassett grad student 2014 CU Boulder
Yemin Xu grad student 2014 CU Boulder
Corinne S. Lengsfeld post-doc 1997-1999 CU Boulder (BME Tree)

Collaborators

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David Faulon Marruecos collaborator 2014-2018 CU Boulder (Neurotree)
BETA: Related publications

Publications

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Preston KB, Monticello CR, Wong TAS, et al. (2020) Preservation of Quaternary Structure in Thermostable, Lyophilized Filovirus Glycoprotein Vaccines: A Search for Stability-Indicating Assays. Journal of Pharmaceutical Sciences
Daniels AL, Calderon CP, Randolph TW. (2020) Machine Learning & Statistical Analyses for Extracting and Characterizing "Fingerprints" of Antibody Aggregation at Container Interfaces from Flow Microscopy Images. Biotechnology and Bioengineering
Movafaghi S, Wu H, Urdániz IMF, et al. (2020) The Effect of Container Surface Passivation on Aggregation of Intravenous Immunoglobulin Induced by Mechanical Shock. Biotechnology Journal. e2000096
Wu H, Randolph TW. (2020) Aggregation and Particle Formation During Pumping of an Antibody Formulation are Controlled by Electrostatic Interactions between Pump Surfaces and Protein Molecules. Journal of Pharmaceutical Sciences
Her C, Tanenbaum L, Bandi S, et al. (2020) Effects of tubing type, operating parameters and surfactants on particle formation during peristaltic filling pump processing of a monoclonal antibody formulation. Journal of Pharmaceutical Sciences
Wu H, Chisholm CF, Puryear M, et al. (2019) Container surfaces control initiation of cavitation and resulting particle formation in protein formulations following application of mechanical shock. Journal of Pharmaceutical Sciences
Snell JR, Monticello CR, Her C, et al. (2019) DEHP Nanodroplets Leached from Polyvinyl Chloride IV Bags Promote Aggregation of IVIG and Activate Complement in Human Serum. Journal of Pharmaceutical Sciences
Snell JR, Kumar NSK, Suryanarayanan R, et al. (2019) Nanobubbles in Reconstituted Lyophilized Formulations: Interaction with Proteins and Mechanism of Formation. Journal of Pharmaceutical Sciences
Wu H, Randolph TW. (2019) Rapid Quantification of Protein Particles in High-Concentration Antibody Formulations. Journal of Pharmaceutical Sciences. 108: 1110-1116
Gandhi AV, Randolph TW, Carpenter JF. (2019) Conjugation of emtansine onto trastuzumab promotes aggregation of the antibody-drug conjugate by reducing repulsive electrostatic interactions and increasing hydrophobic interactions. Journal of Pharmaceutical Sciences
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