Jonathan D. Ashley, Ph.D.

Affiliations: 
2014 Chemical and Biomolecular Engineering University of Notre Dame, Notre Dame, IN, United States 
Area:
Biomedical Engineering, Nanoscience
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"Jonathan Ashley"

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Z. Başar Bilgiçer grad student 2014 Notre Dame (Chemistry Tree)
 (Engineering novel targeted nanoparticle formulations to increase the therapeutic efficacy of conventional chemotherapeutics against multiple myeloma.)
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Publications

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Stefanick JF, Omstead DT, Ashley JD, et al. (2019) Optimizing design parameters of a peptide targeted liposomal nanoparticle in an in vivo multiple myeloma disease model after initial evaluation in vitro. Journal of Controlled Release : Official Journal of the Controlled Release Society
Ashley JD, Quinlan CJ, Schroeder VA, et al. (2016) Dual Carfilzomib and Doxorubicin Loaded Liposomal Nanoparticles for Synergistic Efficacy in Multiple Myeloma. Molecular Cancer Therapeutics
Ashley JD, Stefanick JF, Schroeder VA, et al. (2014) Liposomal carfilzomib nanoparticles effectively target multiple myeloma cells and demonstrate enhanced efficacy in vivo. Journal of Controlled Release : Official Journal of the Controlled Release Society. 196: 113-21
Ashley JD, Stefanick JF, Schroeder VA, et al. (2014) Liposomal bortezomib nanoparticles via boronic ester prodrug formulation for improved therapeutic efficacy in vivo. Journal of Medicinal Chemistry. 57: 5282-92
Noble GT, Stefanick JF, Ashley JD, et al. (2014) Ligand-targeted liposome design: challenges and fundamental considerations. Trends in Biotechnology. 32: 32-45
Stefanick J, Ashley J, Kiziltepe T, et al. (2014) Abstract 5376: Systematic analysis of peptide linker length and liposomal polyethylene glycol coating on cellular uptake of peptide-targeted liposomal nanoparticles Cancer Research. 74: 5376-5376
Stefanick JF, Ashley JD, Bilgicer B. (2013) Enhanced cellular uptake of peptide-targeted nanoparticles through increased peptide hydrophilicity and optimized ethylene glycol peptide-linker length. Acs Nano. 7: 8115-27
Alves NJ, Cusick W, Stefanick JF, et al. (2013) Functionalized liposome purification via Liposome Extruder Purification (LEP). The Analyst. 138: 4746-51
Stefanick JF, Ashley JD, Kiziltepe T, et al. (2013) A systematic analysis of peptide linker length and liposomal polyethylene glycol coating on cellular uptake of peptide-targeted liposomes. Acs Nano. 7: 2935-47
Kiziltepe T, Ashley J, Stefanick J, et al. (2013) Abstract 4524: Designer nanoparticles for selective targeting of multiple myeloma and overcoming CAM-DR. Cancer Research. 73: 4524-4524
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