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Edward M. Greenfield

Affiliations: 
Case Western Reserve University School of Medicine, Cleveland, OH, United States 
Area:
Cell Biology, Biomedical Engineering
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"Edward Greenfield"
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Publications

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Yoshimoto T, Kittaka M, Doan AAP, et al. (2022) Osteocytes directly regulate osteolysis via MYD88 signaling in bacterial bone infection. Nature Communications. 13: 6648
Samsa WE, Mamidi MK, Hausman BS, et al. (2020) The master developmental regulator Jab1/Cops5/Csn5 is essential for proper bone growth and survival in mice. Bone. 115733
Fort BP, Dubyak GR, Greenfield EM. (2020) Lysosomal disruption by orthopaedic wear particles induces activation of the NLRP3 inflammasome and macrophage cell death by distinct mechanisms. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society
Manzano GW, Fort BP, Dubyak GR, et al. (2018) Wear Particle-induced Priming of the NLRP3 Inflammasome Depends on Adherent Pathogen-associated Molecular Patterns and Their Cognate Toll-like Receptors: An In Vitro Study. Clinical Orthopaedics and Related Research. 476: 2442-2453
Bachala D, El-Refai N, Greenfield E, et al. (2018) The Effect of Lunasin on Receptor Activator of Nuclear Factor Kappa-B Ligand−mediated Osteoclast Formation from RAW 264.7 Cells Journal of Endodontics. 44: 997-999
Bechtel CP, Gebhart JJ, Tatro JM, et al. (2016) Particle-Induced Osteolysis Is Mediated by TIRAP/Mal in Vitro and in Vivo: Dependence on Adherent Pathogen-Associated Molecular Patterns. The Journal of Bone and Joint Surgery. American Volume. 98: 285-94
Bonsignore LA, Goldberg VM, Greenfield EM. (2015) Machine oil inhibits the osseointegration of orthopaedic implants by impairing osteoblast attachment and spreading. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 33: 979-87
Chen Z, Yue SX, Zhou G, et al. (2015) ERK1 and ERK2 regulate chondrocyte terminal differentiation during endochondral bone formation. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 30: 765-74
MacInnes SJ, Del Vescovo E, Kiss-Toth E, et al. (2015) Genetic variation in inflammatory and bone turnover pathways and risk of osteolytic responses to prosthetic materials. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 33: 193-8
Greenfield EM. (2014) Do genetic susceptibility, Toll-like receptors, and pathogen-associated molecular patterns modulate the effects of wear? Clinical Orthopaedics and Related Research. 472: 3709-17
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