Danilo Perrotti
Affiliations: | Integrated Biomedical Sciences | Ohio State University, Columbus, Columbus, OH |
Area:
Biomedical EngineeringGoogle:
"Danilo Perrotti"Children
Sign in to add trainee| Anna M. Eiring | grad student | 2009 | Ohio State |
| Joshua J. Oaks | grad student | 2013 | Ohio State |
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Publications
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| Qiao J, Liang C, Zhao D, et al. (2021) Spred1 deficit promotes treatment resistance and transformation of chronic phase CML. Leukemia |
| Scarpa M, Singh P, Bailey CM, et al. (2021) PP2A-activating drugs enhance FLT3 inhibitor efficacy through AKT inhibition-dependent GSK-3β-mediated c-Myc and Pim-1 proteasomal degradation. Molecular Cancer Therapeutics |
| Silvestri G, Trotta R, Stramucci L, et al. (2020) Persistence of Drug-Resistant Leukemic Stem Cells and Impaired NK Cell Immunity in CML Patients Depend on Antiproliferative and PP2A-Activating Functions. Blood Cancer Discovery. 1: 48-67 |
| Silvestri G, Trotta R, Stramucci L, et al. (2020) Persistence of Drug-Resistant Leukemic Stem Cells and Impaired NK Cell Immunity in CML Patients Depend on MIR300 Antiproliferative and PP2A-Activating Functions Blood Cancer Discovery. 1: 48-67 |
| Perrotti D, Agarwal A, Lucas CM, et al. (2019) Comment on "PP2A inhibition sensitizes cancer stem cells to ABL tyrosine kinase inhibitors in BCR-ABL human leukemia". Science Translational Medicine. 11 |
| Silvestri G, Trotta R, Stramucci L, et al. (2019) A 14q32.31 Genomic-Imprinted DLK1-DIO3 microrna promotes Leukemogenesis By Inducing Stem Cell Quiescence and Inhibiting NK Cell Anti-Cancer Immunity Blood. 134: 4141-4141 |
| Scarpa M, Singh P, Kapoor S, et al. (2019) PP2A Activators Enhance Efficacy of FLT3 Inhibitors in FLT3-ITD Acute Myeloid Leukemia Cells through AKT Inactivation-Dependent Pim-1 and c-Myc Proteasomal Degradation Blood. 134: 1276-1276 |
| Srutova K, Curik N, Burda P, et al. (2018) BCR-ABL1 mediated miR-150 downregulation through MYC contributed to myeloid differentiation block and drug resistance in chronic myeloid leukemia. Haematologica |
| Zhang B, Nguyen LXT, Li L, et al. (2018) Bone marrow niche trafficking of miR-126 controls the self-renewal of leukemia stem cells in chronic myelogenous leukemia. Nature Medicine |
| Scarpa M, Kapoor S, Perrotti D, et al. (2018) Concurrent FLT3 Inhibitor and PP2A Activating Drug Treatment Induces Synergistic Cytotoxicity in Acute Myeloid Leukemia Cells with FLT3 Internal Tandem Duplication through Proteasomal Degradation of Pim-1 and c-Myc Blood. 132: 3951-3951 |