Clevio Nóbrega

Affiliations: 
Universitat de Barcelona, Barcelona, Cataluña, Spain 
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"Clevio Nóbrega"
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Marcelo A, Afonso IT, Afonso-Reis R, et al. (2021) Autophagy in Spinocerebellar ataxia type 2, a dysregulated pathway, and a target for therapy. Cell Death & Disease. 12: 1117
Nóbrega C, Conceição A, Costa RG, et al. (2020) The cholesterol 24-hydroxylase activates autophagy and decreases mutant huntingtin build-up in a neuroblastoma culture model of Huntington's disease. Bmc Research Notes. 13: 210
Santana MM, Paixão S, Cunha-Santos J, et al. (2020) Trehalose alleviates the phenotype of Machado-Joseph disease mouse models. Journal of Translational Medicine. 18: 161
Nóbrega C, Mendonça L, Marcelo A, et al. (2019) Restoring brain cholesterol turnover improves autophagy and has therapeutic potential in mouse models of spinocerebellar ataxia. Acta Neuropathologica. 138: 837-858
Mendonça LS, Nóbrega C, Tavino S, et al. (2019) Ibuprofen enhances synaptic function and neural progenitors proliferation markers and improves neuropathology and motor coordination in Machado-Joseph disease models. Human Molecular Genetics
Nóbrega C, Codêsso JM, Mendonça L, et al. (2019) RNA Interference Therapy for Machado-Joseph Disease: Long-Term Safety Profile of Lentiviral Vectors Encoding Short Hairpin RNAs Targeting Mutant Ataxin-3. Human Gene Therapy. 30: 841-854
Marcelo A, Brito F, Carmo-Silva S, et al. (2019) Cordycepin activates autophagy through AMPK phosphorylation to reduce abnormalities in Machado-Joseph disease models. Human Molecular Genetics. 28: 51-63
Matos CA, de Almeida LP, Nóbrega C. (2019) Machado-Joseph disease/spinocerebellar ataxia type 3: lessons from disease pathogenesis and clues into therapy. Journal of Neurochemistry. 148: 8-28
Oliveira Miranda C, Marcelo A, Silva TP, et al. (2018) Repeated Mesenchymal Stromal Cell Treatment Sustainably Alleviates Machado-Joseph Disease. Molecular Therapy : the Journal of the American Society of Gene Therapy
Nóbrega C, Alves S. (2018) Editorial: Gene Silencing and Editing Strategies for Neurodegenerative Diseases. Frontiers in Neuroscience. 12: 425
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