Leah R. Sabin, Ph.D.
Affiliations: | 2011 | University of Pennsylvania, Philadelphia, PA, United States |
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"Leah Sabin"Parents
Sign in to add mentor| Sara Cherry | grad student | 2011 | Penn | |
| (The role of RNA silencing in Drosophila antiviral immunity.) | ||||
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Publications
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| Aguado LC, Schmid S, May J, et al. (2017) RNase III nucleases from diverse kingdoms serve as antiviral effectors. Nature |
| Molleston JM, Sabin LR, Moy RH, et al. (2016) A conserved virus-induced cytoplasmic TRAMP-like complex recruits the exosome to target viral RNA for degradation. Genes & Development. 30: 1658-70 |
| Hopkins KC, Tartell MA, Herrmann C, et al. (2015) Virus-induced translational arrest through 4EBP1/2-dependent decay of 5'-TOP mRNAs restricts viral infection. Proceedings of the National Academy of Sciences of the United States of America. 112: E2920-9 |
| Shapiro JS, Schmid S, Aguado LC, et al. (2014) Drosha as an interferon-independent antiviral factor. Proceedings of the National Academy of Sciences of the United States of America. 111: 7108-13 |
| Xu J, Hopkins K, Sabin L, et al. (2013) ERK signaling couples nutrient status to antiviral defense in the insect gut. Proceedings of the National Academy of Sciences of the United States of America. 110: 15025-30 |
| Sabin LR, Delás MJ, Hannon GJ. (2013) Dogma Derailed: The Many Influences of RNA on the Genome Molecular Cell. 49: 783-794 |
| Sabin LR, Zheng Q, Thekkat P, et al. (2013) Dicer-2 processes diverse viral RNA species. Plos One. 8: e55458 |
| Sabin LR, Cherry S. (2013) Small creatures use small RNAs to direct antiviral defenses. European Journal of Immunology. 43: 27-33 |
| Xu J, Grant G, Sabin LR, et al. (2012) Transcriptional pausing controls a rapid antiviral innate immune response in Drosophila. Cell Host & Microbe. 12: 531-43 |
| Backes S, Shapiro JS, Sabin LR, et al. (2012) Degradation of host microRNAs by poxvirus poly(A) polymerase reveals terminal RNA methylation as a protective antiviral mechanism. Cell Host & Microbe. 12: 200-10 |