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Maisonneuve P, Sahmi M, Bergeron-Labrecque F, et al. (2024) The CNK-HYP scaffolding complex promotes RAF activation by enhancing KSR-MEK interaction. Nature Structural & Molecular Biology |
Serwe G, Kachaner D, Gagnon J, et al. (2023) CNK2 promotes cancer cell motility by mediating ARF6 activation downstream of AXL signalling. Nature Communications. 14: 3560 |
Lavoie H, Therrien M. (2022) Structural keys unlock RAS-MAPK cellular signalling pathway. Nature |
Posternak G, Tang X, Maisonneuve P, et al. (2020) Functional characterization of a PROTAC directed against BRAF mutant V600E. Nature Chemical Biology |
Lavoie H, Gagnon J, Therrien M. (2020) ERK signalling: a master regulator of cell behaviour, life and fate. Nature Reviews. Molecular Cell Biology |
Rauen KA, Schoyer L, Schill L, et al. (2018) Proceedings of the fifth international RASopathies symposium: When development and cancer intersect. American Journal of Medical Genetics. Part A. e40632 |
Lavoie H, Sahmi M, Maisonneuve P, et al. (2018) MEK drives BRAF activation through allosteric control of KSR proteins. Nature |
Jin T, Lavoie H, Sahmi M, et al. (2017) RAF inhibitors promote RAS-RAF interaction by allosterically disrupting RAF autoinhibition. Nature Communications. 8: 1211 |
Kubiniok P, Lavoie H, Therrien M, et al. (2017) Time-resolved phosphoproteome analysis of paradoxical RAF activation reveals novel targets of ERK. Molecular & Cellular Proteomics : McP |
Ashton-Beaucage D, Therrien M. (2017) How Genetics Has Helped Piece Together the MAPK Signaling Pathway. Methods in Molecular Biology (Clifton, N.J.). 1487: 1-21 |