Marc Therrien

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"Marc Therrien"
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Maisonneuve P, Sahmi M, Bergeron-Labrecque F, et al. (2024) The CNK-HYP scaffolding complex promotes RAF activation by enhancing KSR-MEK interaction. Nature Structural & Molecular Biology
Serwe G, Kachaner D, Gagnon J, et al. (2023) CNK2 promotes cancer cell motility by mediating ARF6 activation downstream of AXL signalling. Nature Communications. 14: 3560
Lavoie H, Therrien M. (2022) Structural keys unlock RAS-MAPK cellular signalling pathway. Nature
Posternak G, Tang X, Maisonneuve P, et al. (2020) Functional characterization of a PROTAC directed against BRAF mutant V600E. Nature Chemical Biology
Lavoie H, Gagnon J, Therrien M. (2020) ERK signalling: a master regulator of cell behaviour, life and fate. Nature Reviews. Molecular Cell Biology
Rauen KA, Schoyer L, Schill L, et al. (2018) Proceedings of the fifth international RASopathies symposium: When development and cancer intersect. American Journal of Medical Genetics. Part A. e40632
Lavoie H, Sahmi M, Maisonneuve P, et al. (2018) MEK drives BRAF activation through allosteric control of KSR proteins. Nature
Jin T, Lavoie H, Sahmi M, et al. (2017) RAF inhibitors promote RAS-RAF interaction by allosterically disrupting RAF autoinhibition. Nature Communications. 8: 1211
Kubiniok P, Lavoie H, Therrien M, et al. (2017) Time-resolved phosphoproteome analysis of paradoxical RAF activation reveals novel targets of ERK. Molecular & Cellular Proteomics : McP
Ashton-Beaucage D, Therrien M. (2017) How Genetics Has Helped Piece Together the MAPK Signaling Pathway. Methods in Molecular Biology (Clifton, N.J.). 1487: 1-21
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