Igor Tatarnikov

Affiliations: 
2012- Medical Genetics University of British Columbia, Vancouver, Vancouver, BC, Canada 
Area:
Parkinson's, Electrophysiology, Neurodegeneration, Neuroscience
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"Igor Tatarnikov"

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Matthew Farrer grad student 2015- UBC (Neurotree)
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Publications

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Bu M, Follett J, Deng I, et al. (2023) Inhibition of LRRK2 kinase activity rescues deficits in striatal dopamine physiology in VPS35 p.D620N knock-in mice. Npj Parkinson's Disease. 9: 167
Follett J, Fox JD, Gustavsson EK, et al. (2019) DNAJC13 p.Asn855Ser, implicated in familial parkinsonism, alters membrane dynamics of Sorting Nexin 1. Neuroscience Letters
Cataldi S, Follett J, Fox JD, et al. (2018) Altered dopamine release and monoamine transporters in Vps35 p.D620N knock-in mice. Npj Parkinson's Disease. 4: 27
Volta M, Beccano-Kelly DA, Paschall SA, et al. (2017) Initial elevations in glutamate and dopamine neurotransmission decline with age, as does exploratory behavior, in LRRK2 G2019S knock-in mice. Elife. 6
Volta M, Beccano-Kelly DA, Paschall SA, et al. (2017) Author response: Initial elevations in glutamate and dopamine neurotransmission decline with age, as does exploratory behavior, in LRRK2 G2019S knock-in mice Elife
Volta M, Cataldi S, Beccano-Kelly D, et al. (2015) Chronic and acute LRRK2 silencing has no long-term behavioral effects, whereas wild-type and mutant LRRK2 overexpression induce motor and cognitive deficits and altered regulation of dopamine release. Parkinsonism & Related Disorders. 21: 1156-63
Munsie LN, Milnerwood AJ, Seibler P, et al. (2015) Retromer-dependent neurotransmitter receptor trafficking to synapses is altered by the Parkinson's disease VPS35 mutation p.D620N. Human Molecular Genetics. 24: 1691-703
Beccano-Kelly DA, Volta M, Munsie LN, et al. (2015) LRRK2 overexpression alters glutamatergic presynaptic plasticity, striatal dopamine tone, postsynaptic signal transduction, motor activity and memory. Human Molecular Genetics. 24: 1336-49
Beccano-Kelly DA, Kuhlmann N, Tatarnikov I, et al. (2014) Synaptic function is modulated by LRRK2 and glutamate release is increased in cortical neurons of G2019S LRRK2 knock-in mice. Frontiers in Cellular Neuroscience. 8: 301
Vilariño-Güell C, Rajput A, Milnerwood AJ, et al. (2014) DNAJC13 mutations in Parkinson disease. Human Molecular Genetics. 23: 1794-801
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