Megan Mayerle, Ph.D.
Affiliations: | 2012 | Biology | Johns Hopkins University, Baltimore, MD |
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"Megan Mayerle"Parents
Sign in to add mentor| Sarah Woodson | grad student | 2012 | Johns Hopkins | |
| (Specific contacts between ribosomal protein S4 and RNA are necessary for proper ribosome assembly.) | ||||
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Publications
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| Mayerle M, Yitiz S, Soulette C, et al. (2019) Prp8 impacts cryptic but not alternative splicing frequency. Proceedings of the National Academy of Sciences of the United States of America |
| MacRae AJ, Mayerle M, Hrabeta-Robinson E, et al. (2018) Prp8 positioning of U5 snRNA is linked to 5' splice site recognition. Rna (New York, N.Y.) |
| MacRae A, Mayerle M, Chalkley R, et al. (2018) A Flexible Region of PRP8 Interacts with U5 snRNA Loop I and is Functionally Linked to 5' Splice Site Recognition Biophysical Journal. 114: 253a |
| Mayerle M, Raghavan M, Ledoux S, et al. (2017) Structural toggle in the RNaseH domain of Prp8 helps balance splicing fidelity and catalytic efficiency. Proceedings of the National Academy of Sciences of the United States of America |
| Mayerle M, Guthrie C. (2017) Genetics and Biochemistry Remain Essential in the Structural Era of the Spliceosome. Methods (San Diego, Calif.) |
| Mayerle M, Guthrie C. (2016) Prp8 retinitis pigmentosa mutants cause defects in the transition between the catalytic steps of splicing. Rna (New York, N.Y.) |
| Mayerle M, Guthrie C. (2016) A new communication hub in the RNA world. Nature Structural & Molecular Biology. 23: 189-90 |
| Kim H, Abeysirigunawarden SC, Chen K, et al. (2014) Protein-guided RNA dynamics during early ribosome assembly. Nature. 506: 334-8 |
| Mayerle M, Abelson J, Guthrie C. (2014) Development of an smFRET Assay to Monitor Spliceosome Activation in Budding Yeast Biophysical Journal. 106: 496a |
| Mayerle M, Woodson SA. (2013) Specific contacts between protein S4 and ribosomal RNA are required at multiple stages of ribosome assembly. Rna (New York, N.Y.). 19: 574-85 |