Tom Van Lee, Ph.D.

Affiliations: 
Molecular and Human Genetics Baylor College of Medicine, Houston, TX 
Area:
Notch signaling, Developmental Glycobiology
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"Tom Lee"

Parents

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Andreas Bergmann grad student 2003-2008 The University of Texas Graduate School of Biomedical Sciences at Houston
 (Analysis of the E1-ubiquitin activating enzyme, Uba1, in cell death and tissue growth in Drosophila.)
Hamed Jafar-Nejad post-doc 2012- Baylor College of Medicine
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Publications

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Shields A, Amcheslavsky A, Brown E, et al. (2022) Toll-9 interacts with Toll-1 to mediate a feedback loop during apoptosis-induced proliferation in Drosophila. Cell Reports. 39: 110817
Ojelade SA, Lee TV, Giagtzoglou N, et al. (2019) cindr, the Drosophila Homolog of the CD2AP Alzheimer's Disease Risk Gene, Is Required for Synaptic Transmission and Proteostasis. Cell Reports. 28: 1799-1813.e5
Pandey A, Li-Kroeger D, Sethi MK, et al. (2018) Sensitized genetic backgrounds reveal differential roles for EGF repeat xylosyltransferases in Drosophila Notch signaling. Glycobiology
Lee TV, Pandey A, Jafar-Nejad H. (2017) Xylosylation of the Notch receptor preserves the balance between its activation by trans-Delta and inhibition by cis-ligands in Drosophila. Plos Genetics. 13: e1006723
Ojelade SA, Lee TV, Giagtzoglou N, et al. (2017) [O2-18-04]: THE ALZHEIMER's DISEASE SUSCEPTIBILITY GENE CD2AP REGULATES PRESYNAPTIC FUNCTION Alzheimer's & Dementia. 13: P603-P603
Servián-Morilla E, Takeuchi H, Lee TV, et al. (2016) A POGLUT1 mutation causes a muscular dystrophy with reduced Notch signaling and satellite cell loss. Embo Molecular Medicine. 8: 1289-1309
Lee TV, Kamber Kaya HE, Simin R, et al. (2016) The initiator caspase Dronc is subject of enhanced autophagy upon proteasome impairment in Drosophila. Cell Death and Differentiation
Lee TV, Jafar-Nejad H. (2015) O-Glucose Glycans in Drosophila Notch Signaling Glycoscience: Biology and Medicine. 849-856
Haltom AR, Lee TV, Harvey BM, et al. (2014) The protein O-glucosyltransferase Rumi modifies eyes shut to promote rhabdomere separation in Drosophila. Plos Genetics. 10: e1004795
LeBon L, Lee TV, Sprinzak D, et al. (2014) Fringe proteins modulate Notch-ligand cis and trans interactions to specify signaling states. Elife. 3: e02950
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