Nazif Alic, PhD.

Affiliations: 
Institute of Healthy Ageing University College London, London, United Kingdom 
Area:
Ageing
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"Nazif Alic"
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Publications

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Malik Y, Goncalves Silva I, Diazgranados RR, et al. (2024) Timing of TORC1 inhibition dictates Pol III involvement in longevity. Life Science Alliance. 7
Borland G, Wilkie SE, Thomson J, et al. (2024) Polr3b heterozygosity in mice induces both beneficial and deleterious effects on health during ageing with no effect on lifespan. Aging Cell. e14141
Ureña E, Xu B, Regan JC, et al. (2024) Trametinib ameliorates aging-associated gut pathology in females by reducing Pol III activity in intestinal stem cells. Proceedings of the National Academy of Sciences of the United States of America. 121: e2311313121
Javidnia S, Cranwell S, Mueller SH, et al. (2022) Mendelian randomization analyses implicate biogenesis of translation machinery in human aging. Genome Research. 32: 258-265
Martínez Corrales G, Alic N. (2020) Evolutionary Conservation of Transcription Factors Affecting Longevity. Trends in Genetics : Tig. 36: 373-382
Woodling NS, Aleyakpo B, Dyson MC, et al. (2020) The neuronal receptor tyrosine kinase Alk is a target for longevity. Aging Cell. e13137
Bettedi L, Yan A, Schuster E, et al. (2020) Increased mitochondrial and lipid metabolism is a conserved effect of Insulin/PI3K pathway downregulation in adipose tissue. Scientific Reports. 10: 3418
Martínez Corrales G, Filer D, Wenz KC, et al. (2020) Partial Inhibition of RNA Polymerase I Promotes Animal Health and Longevity. Cell Reports. 30: 1661-1669.e4
Dobson AJ, Boulton-McDonald R, Houchou L, et al. (2019) Longevity is determined by ETS transcription factors in multiple tissues and diverse species. Plos Genetics. 15: e1008212
Filer D, Thompson MA, Takhaveev V, et al. (2017) RNA polymerase III limits longevity downstream of TORC1. Nature. 552: 263-267
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