Parents
Sign in to add mentor| Ian Duncan | grad student | Washington University | |
| Spyros Artavanis-Tsakonas | post-doc | Harvard Medical School |
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Publications
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| May-Dracka TL, Gao F, Hopkins BT, et al. (2022) Discovery of Phospholipase D Inhibitors with Improved Drug-like Properties and Central Nervous System Penetrance. Acs Medicinal Chemistry Letters. 13: 665-673 |
| Kankel MW, Sen A, Lu L, et al. (2020) Amyotrophic Lateral Sclerosis Modifiers in Reveal the Phospholipase D Pathway as a Potential Therapeutic Target. Genetics |
| Krishnan G, Zhang Y, Gu Y, et al. (2020) CRISPR deletion of the C9ORF72 promoter in ALS/FTD patient motor neurons abolishes production of dipeptide repeat proteins and rescues neurodegeneration. Acta Neuropathologica |
| Sarraf SA, Sideris DP, Giagtzoglou N, et al. (2019) PINK1/Parkin Influences Cell Cycle by Sequestering TBK1 at Damaged Mitochondria, Inhibiting Mitosis. Cell Reports. 29: 225-235.e5 |
| Chen H, Kankel MW, Su SC, et al. (2018) Exploring the genetics and non-cell autonomous mechanisms underlying ALS/FTLD. Cell Death and Differentiation |
| Markmiller S, Soltanieh S, Server KL, et al. (2018) Context-Dependent and Disease-Specific Diversity in Protein Interactions within Stress Granules. Cell. 172: 590-604.e13 |
| Periz G, Lu J, Zhang T, et al. (2015) Regulation of protein quality control by UBE4B and LSD1 through p53-mediated transcription. Plos Biology. 13: e1002114 |
| Sen A, Dimlich DN, Guruharsha KG, et al. (2013) Genetic circuitry of Survival motor neuron, the gene underlying spinal muscular atrophy. Proceedings of the National Academy of Sciences of the United States of America. 110: E2371-80 |
| Guruharsha KG, Kankel MW, Artavanis-Tsakonas S. (2012) The Notch signalling system: recent insights into the complexity of a conserved pathway. Nature Reviews. Genetics. 13: 654-66 |
| Sen A, Yokokura T, Kankel MW, et al. (2011) Modeling spinal muscular atrophy in Drosophila links Smn to FGF signaling. The Journal of Cell Biology. 192: 481-95 |