Jessica L. Simmers, Ph.D.

Affiliations: 
2013 Johns Hopkins University, Baltimore, MD 
Area:
Genetics, Molecular Biology, Physiology Biology
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"Jessica Simmers"

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Ronald Cohn grad student 2013 Johns Hopkins
 (nNos localization, muscle function and atrophy in skeletal muscle disorders.)
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Publications

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Auer DR, Sysa-Shah P, Bedja D, et al. (2014) Generation of a cre recombinase-conditional Nos1ap over-expression transgenic mouse. Biotechnology Letters. 36: 1179-85
MacDonald EM, Andres-Mateos E, Mejias R, et al. (2014) Denervation atrophy is independent from Akt and mTOR activation and is not rescued by myostatin inhibition. Disease Models & Mechanisms. 7: 471-81
Andres-Mateos E, Brinkmeier H, Burks TN, et al. (2013) Activation of serum/glucocorticoid-induced kinase 1 (SGK1) is important to maintain skeletal muscle homeostasis and prevent atrophy. Embo Molecular Medicine. 5: 80-91
Files DC, D'Alessio FR, Johnston LF, et al. (2012) A critical role for muscle ring finger-1 in acute lung injury-associated skeletal muscle wasting. American Journal of Respiratory and Critical Care Medicine. 185: 825-34
Burks T, Lucas O, Andres-Mateos E, et al. (2012) T.O.8 Age-dependent effects of angiotensin II blockade on disuse atrophy Neuromuscular Disorders. 22: 908
MacDonald E, Simmers J, Andres-Mateos E, et al. (2012) T.O.6 Myostatin inhibitor ActIIb rescues atrophy and protects muscle growth signaling pathways in immobilization but not denervation Neuromuscular Disorders. 22: 908
Simmers JL, Chaerkady R, Hedderick EF, et al. (2012) G.P.84 Mislocalization of nNOS alters the interactions between nNOS and proteins involved with muscle contraction in steroid-induced myopathy Neuromuscular Disorders. 22: 837
Burks TN, Andres-Mateos E, Marx R, et al. (2011) Losartan restores skeletal muscle remodeling and protects against disuse atrophy in sarcopenia. Science Translational Medicine. 3: 82ra37
Finanger Hedderick EL, Simmers JL, Soleimani A, et al. (2011) Loss of sarcolemmal nNOS is common in acquired and inherited neuromuscular disorders. Neurology. 76: 960-7
Burks T, Andres-Mateos E, Simmers J, et al. (2010) P3.47 Administration of Losartan improves skeletal muscle repair in mice with sarcopenia Neuromuscular Disorders. 20: 655
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