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Hee Y. Seok, Ph.D.

Affiliations: 
2011 Cell & Developmental Biology University of North Carolina, Chapel Hill, Chapel Hill, NC 
Area:
Genetics, Molecular Biology, Human Development
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"Hee Seok"
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Da-Zhi Wang grad student 2011 UNC Chapel Hill
 (Regulation of cardiac development by RNA helicase and microRNAs.)

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Publications

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Guo H, Lu YW, Lin Z, et al. (2020) Intercalated disc protein Xinβ is required for Hippo-YAP signaling in the heart. Nature Communications. 11: 4666
Nie M, Liu J, Yang Q, et al. (2016) MicroRNA-155 facilitates skeletal muscle regeneration by balancing pro- and anti-inflammatory macrophages. Cell Death & Disease. 7: e2261
Seok HY, Chen J, Kataoka M, et al. (2014) Loss of MicroRNA-155 protects the heart from pathological cardiac hypertrophy. Circulation Research. 114: 1585-95
Chen J, Huang ZP, Seok HY, et al. (2013) mir-17-92 cluster is required for and sufficient to induce cardiomyocyte proliferation in postnatal and adult hearts. Circulation Research. 112: 1557-66
Huang ZP, Chen J, Seok HY, et al. (2013) MicroRNA-22 regulates cardiac hypertrophy and remodeling in response to stress. Circulation Research. 112: 1234-43
Seok HY, Tatsuguchi M, Callis TE, et al. (2011) miR-155 inhibits expression of the MEF2A protein to repress skeletal muscle differentiation. The Journal of Biological Chemistry. 286: 35339-46
Seok HY, Wang DZ. (2010) The emerging role of microRNAs as a therapeutic target for cardiovascular disease. Biodrugs : Clinical Immunotherapeutics, Biopharmaceuticals and Gene Therapy. 24: 147-55
Callis TE, Pandya K, Seok HY, et al. (2009) MicroRNA-208a is a regulator of cardiac hypertrophy and conduction in mice. The Journal of Clinical Investigation. 119: 2772-86
Tatsuguchi M, Seok HY, Callis TE, et al. (2007) Expression of microRNAs is dynamically regulated during cardiomyocyte hypertrophy Journal of Molecular and Cellular Cardiology. 42: 1137-1141
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