Ann Dean, Ph.D.
Affiliations: | Gene Regulation and Development | National Institute of Diabetes and Digestive and Kidney Diseases |
Area:
Cellular and Developmental BiologyWebsite:
https://irp.nih.gov/pi/ann-deanGoogle:
"Ann Dean"Bio:
Parents
Sign in to add mentorAlan N. Schechter | grad student | 1981 | George Washington University (Physics Tree) | |
(Development of specific radioimmunoassays for human hemoglobins and their application in the study of hemoglobin biosynthesis in culture) |
Children
Sign in to add traineeJane A. Little | post-doc | National Institute of Diabetes and Digestive and Kidney Diseases (Stem Cell Tree) |
BETA: Related publications
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Publications
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Liu G, Kim J, Nguyen NH, et al. (2024) Long noncoding RNA GATA2AS influences human erythropoiesis by transcription factor and chromatin landscape regulation. Blood |
Xie B, Dean A. (2023) Noncoding function of super enhancer derived mRNA in modulating neighboring gene expression and TAD interaction. Biorxiv : the Preprint Server For Biology |
Liu G, Wang L, Wess J, et al. (2022) Enhancer looping protein LDB1 regulates hepatocyte gene expression by cooperating with liver transcription factors. Nucleic Acids Research |
Guo X, Dean A, Zhao Y, et al. (2022) Hemogen /BRG1 cooperativity modulates promoter and enhancer activation during erythropoiesis. Blood |
Kim J, Dean A. (2021) A Zinc Finger Transcription Factor Faithfully Dedicated to Only a Single Target Gene in Erythroid Cells. Molecular Cell. 81: 218-219 |
Guo X, Plank-Bazinet J, Krivega I, et al. (2020) Embryonic erythropoiesis and hemoglobin switching require transcriptional repressor ETO2 to modulate chromatin organization. Nucleic Acids Research |
Chambers CB, Gross J, Pratt K, et al. (2020) The mRNA-Binding Protein IGF2BP1 Restores Fetal Hemoglobin in Cultured Erythroid Cells from Patients with β-Hemoglobin Disorders. Molecular Therapy. Methods & Clinical Development. 17: 429-440 |
Wang H, Kim J, Wang Z, et al. (2019) Crystal structure of human LDB1 in complex with SSBP2. Proceedings of the National Academy of Sciences of the United States of America |
Liu G, Dean A. (2019) Enhancer long-range contacts: The multi-adaptor protein LDB1 is the tie that binds. Biochimica Et Biophysica Acta. Gene Regulatory Mechanisms |
Guo X, Dean A. (2018) CRISPR/Cas9 offers a new tool for studying the role of chromatin architecture in disease pathogenesis. Genome Biology. 19: 185 |