Ann Dean, Ph.D.

Affiliations: 
Gene Regulation and Development National Institute of Diabetes and Digestive and Kidney Diseases 
Area:
Cellular and Developmental Biology
Website:
https://irp.nih.gov/pi/ann-dean
Google:
"Ann Dean"
Bio:

DOI: 10.1073/pnas.80.18.5515

Parents

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Alan N. Schechter grad student 1981 George Washington University (Physics Tree)
 (Development of specific radioimmunoassays for human hemoglobins and their application in the study of hemoglobin biosynthesis in culture)
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Publications

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Liu G, Kim J, Nguyen NH, et al. (2024) Long noncoding RNA GATA2AS influences human erythropoiesis by transcription factor and chromatin landscape regulation. Blood
Xie B, Dean A. (2023) Noncoding function of super enhancer derived mRNA in modulating neighboring gene expression and TAD interaction. Biorxiv : the Preprint Server For Biology
Liu G, Wang L, Wess J, et al. (2022) Enhancer looping protein LDB1 regulates hepatocyte gene expression by cooperating with liver transcription factors. Nucleic Acids Research
Guo X, Dean A, Zhao Y, et al. (2022) Hemogen /BRG1 cooperativity modulates promoter and enhancer activation during erythropoiesis. Blood
Kim J, Dean A. (2021) A Zinc Finger Transcription Factor Faithfully Dedicated to Only a Single Target Gene in Erythroid Cells. Molecular Cell. 81: 218-219
Guo X, Plank-Bazinet J, Krivega I, et al. (2020) Embryonic erythropoiesis and hemoglobin switching require transcriptional repressor ETO2 to modulate chromatin organization. Nucleic Acids Research
Chambers CB, Gross J, Pratt K, et al. (2020) The mRNA-Binding Protein IGF2BP1 Restores Fetal Hemoglobin in Cultured Erythroid Cells from Patients with β-Hemoglobin Disorders. Molecular Therapy. Methods & Clinical Development. 17: 429-440
Wang H, Kim J, Wang Z, et al. (2019) Crystal structure of human LDB1 in complex with SSBP2. Proceedings of the National Academy of Sciences of the United States of America
Liu G, Dean A. (2019) Enhancer long-range contacts: The multi-adaptor protein LDB1 is the tie that binds. Biochimica Et Biophysica Acta. Gene Regulatory Mechanisms
Guo X, Dean A. (2018) CRISPR/Cas9 offers a new tool for studying the role of chromatin architecture in disease pathogenesis. Genome Biology. 19: 185
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