David Jonathan Owen

Affiliations: 
Cambridge Institute for Medical research 
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"David Owen"
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Cattin-Ortolá J, Kaufman JGG, Gillingham AK, et al. (2024) Cargo selective vesicle tethering: The structural basis for binding of specific cargo proteins by the Golgi tether component TBC1D23. Science Advances. 10: eadl0608
Zaccai NR, Kadlecova Z, Dickson VK, et al. (2022) FCHO controls AP2's initiating role in endocytosis through a PtdIns(4,5)P-dependent switch. Science Advances. 8: eabn2018
Bowman SL, Le L, Zhu Y, et al. (2021) A BLOC-1-AP-3 super-complex sorts a cis-SNARE complex into endosome-derived tubular transport carriers. The Journal of Cell Biology. 220
Leneva N, Kovtun O, Morado DR, et al. (2021) Architecture and mechanism of metazoan retromer:SNX3 tubular coat assembly. Science Advances. 7
Crawley-Snowdon H, Yang JC, Zaccai NR, et al. (2020) Mechanism and evolution of the Zn-fingernail required for interaction of VARP with VPS29. Nature Communications. 11: 5031
Kovtun O, Dickson VK, Kelly BT, et al. (2020) Architecture of the AP2/clathrin coat on the membranes of clathrin-coated vesicles. Science Advances. 6: eaba8381
Wrobel AG, Kadlecova Z, Kamenicky J, et al. (2019) Temporal Ordering in Endocytic Clathrin-Coated Vesicle Formation via AP2 Phosphorylation. Developmental Cell. 50: 494-508.e11
Kovtun O, Leneva N, Bykov YS, et al. (2018) Structure of the membrane-assembled retromer coat determined by cryo-electron tomography. Nature
Ma L, Umasankar PK, Wrobel AG, et al. (2016) Transient Fcho1/2⋅Eps15/R⋅AP-2 Nanoclusters Prime the AP-2 Clathrin Adaptor for Cargo Binding. Developmental Cell
Kelly BT, Graham SC, Owen DJ. (2016) Using selenomethionyl derivatives to assign sequence in low-resolution structures of the AP2 clathrin adaptor. Acta Crystallographica. Section D, Structural Biology. 72: 336-45
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