Jacqueline K. Lekostaj, Ph.D.
Affiliations: | 2008 | Tumor Biology | Georgetown University, Washington, DC |
Area:
Parasitology, Biochemistry, Molecular BiologyGoogle:
"Jacqueline Lekostaj"Parents
Sign in to add mentor| Paul D. Roepe | grad student | 2008 | Georgetown | |
| (Molecular analysis of membrane transporters implicated in drug resistance.) | ||||
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Publications
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| Pleeter P, Lekostaj JK, Roepe PD. (2010) Purified Plasmodium falciparum multi-drug resistance protein (PfMDR 1) binds a high affinity chloroquine analogue. Molecular and Biochemical Parasitology. 173: 158-61 |
| Lekostaj JK, Natarajan JK, Paguio MF, et al. (2008) Photoaffinity labeling of the Plasmodium falciparum chloroquine resistance transporter with a novel perfluorophenylazido chloroquine. Biochemistry. 47: 10394-406 |
| Lekostaj JK, Amoah LE, Roepe PD. (2008) A single S1034C mutation confers altered drug sensitivity to PfMDR1 ATPase activity that is characteristic of the 7G8 isoform. Molecular and Biochemical Parasitology. 157: 107-11 |
| Amoah LE, Lekostaj JK, Roepe PD. (2007) Heterologous expression and ATPase activity of mutant versus wild type PfMDR1 protein. Biochemistry. 46: 6060-73 |