Rustom Falahati, Ph.D.
Affiliations: | 2007 | The George Washington University, Washington, DC, United States |
Area:
Molecular Biology, Microbiology, SystematicGoogle:
"Rustom Falahati"Parents
Sign in to add mentor| David Leitenberg | grad student | 2007 | The George Washington University | |
| (Regulation of the CD45 protein tyrosine phosphatase.) | ||||
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Publications
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| Youngblood BA, Leung J, Falahati R, et al. (2020) Discovery, Function, and Therapeutic Targeting of Siglec-8. Cells. 10 |
| Schanin J, Gebremeskel S, Korver W, et al. (2020) A monoclonal antibody to Siglec-8 suppresses non-allergic airway inflammation and inhibits IgE-independent mast cell activation. Mucosal Immunology |
| Youngblood BA, Brock EC, Leung J, et al. (2019) Siglec-8 antibody reduces eosinophil and mast cell infiltration in a transgenic mouse model of eosinophilic gastroenteritis. Jci Insight |
| Youngblood BA, Brock EC, Leung J, et al. (2019) AK002, a Humanized Sialic Acid-Binding Immunoglobulin-Like Lectin-8 Antibody that Induces Antibody-Dependent Cell-Mediated Cytotoxicity against Human Eosinophils and Inhibits Mast Cell-Mediated Anaphylaxis in Mice. International Archives of Allergy and Immunology. 1-12 |
| Bryce PJ, Falahati R, Kenney LL, et al. (2016) Humanized mouse model of mast cell-mediated passive cutaneous anaphylaxis and passive systemic anaphylaxis. The Journal of Allergy and Clinical Immunology |
| Falahati R, Bright J, Dorenbaum A, et al. (2015) A Recombinant Antibody to Siglec-8 Shows Selective ADCC Activity Against Mast Cells from Systemic Mastocytosis Patients Blood. 126: 4092-4092 |
| Shi Y, Falahati R, Zhang J, et al. (2013) Role of antigen-specific regulatory CD4+ CD25+ T cells in tolerance induction after neonatal IP administration of AAV-hF.IX Gene Therapy. 20: 987-996 |
| Falahati R, Zhang J, Flebbe-Rehwaldt L, et al. (2012) Chemoselection of allogeneic HSC after murine neonatal transplantation without myeloablation or post-transplant immunosuppression. Molecular Therapy : the Journal of the American Society of Gene Therapy. 20: 2180-9 |
| Jales A, Falahati R, Mari E, et al. (2011) Ganglioside-exposed dendritic cells inhibit T-cell effector function by promoting regulatory cell activity. Immunology. 132: 134-43 |
| Hacke K, Falahati R, Flebbe-Rehwaldt L, et al. (2009) Suppression of HLA expression by lentivirus-mediated gene transfer of siRNA cassettes and in vivo chemoselection to enhance hematopoietic stem cell transplantation. Immunologic Research. 44: 112-26 |