Kevin W. Tinsley, Ph.D.
Affiliations: | 2009 | Biomedical Sciences | The George Washington University, Washington, DC, United States |
Area:
Molecular Biology, Microbiology, SystematicGoogle:
"Kevin Tinsley"Parents
Sign in to add mentor| David Leitenberg | grad student | 2009 | The George Washington University | |
| (CD4 dependent signaling regulates T-helper effector functions and cell death.) | ||||
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Publications
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| Tinsley KW, Hong C, Luckey MA, et al. (2013) Ikaros is required to survive positive selection and to maintain clonal diversity during T-cell development in the thymus. Blood. 122: 2358-68 |
| Furumoto Y, Charles N, Olivera A, et al. (2011) PTEN deficiency in mast cells causes a mastocytosis-like proliferative disease that heightens allergic responses and vascular permeability. Blood. 118: 5466-75 |
| Tinsley KW, Herzog D, Leitenberg D. (2011) CD4 co-receptor dependent signaling promotes competency for re-stimulation induced cell death of effector T cells. Cellular Immunology. 266: 200-7 |
| Tatari-Calderone Z, Brogdon JL, Tinsley KW, et al. (2005) CD4-dependent signaling is required for a late checkpoint during Th2 development associated with resistance to activation-induced cell death. Journal of Immunology (Baltimore, Md. : 1950). 175: 5629-36 |
| Efron PA, Martins A, Minnich D, et al. (2004) Characterization of the systemic loss of dendritic cells in murine lymph nodes during polymicrobial sepsis. Journal of Immunology (Baltimore, Md. : 1950). 173: 3035-43 |
| Bommhardt U, Chang KC, Swanson PE, et al. (2004) Akt decreases lymphocyte apoptosis and improves survival in sepsis. Journal of Immunology (Baltimore, Md. : 1950). 172: 7583-91 |
| Tinsley KW, Grayson MH, Swanson PE, et al. (2003) Sepsis induces apoptosis and profound depletion of splenic interdigitating and follicular dendritic cells. Journal of Immunology (Baltimore, Md. : 1950). 171: 909-14 |
| Hotchkiss RS, Chang KC, Grayson MH, et al. (2003) Adoptive transfer of apoptotic splenocytes worsens survival, whereas adoptive transfer of necrotic splenocytes improves survival in sepsis. Proceedings of the National Academy of Sciences of the United States of America. 100: 6724-9 |
| Hotchkiss RS, Tinsley KW, Swanson PE, et al. (2001) Sepsis-induced apoptosis causes progressive profound depletion of B and CD4+ T lymphocytes in humans. Journal of Immunology (Baltimore, Md. : 1950). 166: 6952-63 |
| Tinsley K, Swanson P, Coopersmith C, et al. (2001) SEPSIS CAUSES LOSS OF CD3 T CELLS, B CELLS, AND LYMPHOID FOLLICLES. Shock. 15: 18-19 |