Jay K. Wathen, Ph.D.

Affiliations: 
2005 The University of Texas Graduate School of Biomedical Sciences at Houston 
Area:
Statistics, Biostatistics Biology
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Peter F. Thall grad student 2005 The University of Texas Graduate School of Biomedical Sciences at Houston
 (Bayesian doubly optimal group sequential designs for randomized clinical trials.)
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Publications

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Wathen JK, Thall PF. (2017) A simulation study of outcome adaptive randomization in multi-arm clinical trials. Clinical Trials (London, England). 14: 432-440
Schuetze SM, Wathen JK, Lucas DR, et al. (2015) SARC009: Phase 2 study of dasatinib in patients with previously treated, high-grade, advanced sarcoma. Cancer
Thall P, Fox P, Wathen J. (2015) Statistical controversies in clinical research: scientific and ethical problems with adaptive randomization in comparative clinical trials. Annals of Oncology : Official Journal of the European Society For Medical Oncology / Esmo. 26: 1621-8
Morgan CC, Huyck S, Jenkins M, et al. (2014) Adaptive Design: Results of 2012 Survey on Perception and Use Therapeutic Innovation and Regulatory Science. 48: 473-481
Lionberger JM, Dorcy KS, Dean C, et al. (2011) Innovative Phase I/II Statistical Design in Combination Chemotherapy That Combines Toxicity and Efficacy Parameters to Increase Study Efficiency: Bendamustine and Idarubicin in De Novo Adult AML Blood. 118: 1552-1552
Chugh R, Wathen JK, Patel SR, et al. (2010) Efficacy of imatinib in aggressive fibromatosis: Results of a phase II multicenter Sarcoma Alliance for Research through Collaboration (SARC) trial. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 16: 4884-91
Wathen JK, Thall PF. (2008) Bayesian adaptive model selection for optimizing group sequential clinical trials. Statistics in Medicine. 27: 5586-604
Thall PF, Wathen JK. (2008) Bayesian designs to account for patient heterogeneity in phase II clinical trials. Current Opinion in Oncology. 20: 407-11
Wathen JK, Thall PF, Cook JD, et al. (2008) Accounting for patient heterogeneity in phase II clinical trials. Statistics in Medicine. 27: 2802-15
Maki RG, Wathen JK, Patel SR, et al. (2007) Randomized phase II study of gemcitabine and docetaxel compared with gemcitabine alone in patients with metastatic soft tissue sarcomas: results of sarcoma alliance for research through collaboration study 002 [corrected]. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 25: 2755-63
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