Lawrence Chasin
Affiliations: | Columbia University, New York, NY |
Area:
Molecular Biology, Biostatistics Biology, GeneticsGoogle:
"Lawrence Chasin"Children
Sign in to add trainee| Hanzhen Sun | grad student | 2000 | Columbia |
| Shengdong Ke | grad student | 2011 | Columbia |
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Publications
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| Ke S, Anquetil V, Zamalloa JR, et al. (2017) Saturation mutagenesis reveals manifold determinants of exon definition. Genome Research |
| Solé A, Ciudad CJ, Chasin LA, et al. (2016) Correction of point mutations at the endogenous locus of the dihydrofolate reductase gene using repair-PolyPurine Reverse Hoogsteen hairpins in mammalian cells. Biochemical Pharmacology |
| Arias MA, Lubkin A, Chasin LA. (2015) Splicing of designer exons informs a biophysical model for exon definition. Rna (New York, N.Y.). 21: 213-29 |
| Ke S, Shang S, Kalachikov SM, et al. (2011) Quantitative evaluation of all hexamers as exonic splicing elements. Genome Research. 21: 1360-74 |
| Ke S, Chasin LA. (2011) Context-dependent splicing regulation: exon definition, co-occurring motif pairs and tissue specificity. Rna Biology. 8: 384-8 |
| Ke S, Chasin LA. (2010) Intronic motif pairs cooperate across exons to promote pre-mRNA splicing. Genome Biology. 11: R84 |
| Arias MA, Ke S, Chasin LA. (2010) Splicing by cell type. Nature Biotechnology. 28: 686-7 |
| Zhang XH, Arias MA, Ke S, et al. (2009) Splicing of designer exons reveals unexpected complexity in pre-mRNA splicing. Rna (New York, N.Y.). 15: 367-76 |
| Yu Y, Maroney PA, Denker JA, et al. (2008) Dynamic Regulation of Alternative Splicing by Silencers that Modulate 5′ Splice Site Competition Cell. 135: 1224-1236 |
| Ke S, Zhang XH, Chasin LA. (2008) Positive selection acting on splicing motifs reflects compensatory evolution. Genome Research. 18: 533-43 |