William R. Roush

Affiliations: 
1978-1987 Massachusetts Institute of Technology, Cambridge, MA, United States 
 1987-1997 Indiana University, Bloomington, Bloomington, IN, United States 
 1997-2004 University of Michigan, Ann Arbor, Ann Arbor, MI 
 2004- Chemistry Scripps Research Institute Florida 
Area:
Medicinal Chemistry
Website:
http://www.scripps.edu/roush/Roush.html
Google:
"William R. Roush"
Bio:

http://um2017.org/faculty-history/faculty/william-r-roush

Cross-listing: Chemistry Tree

Parents

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Julius Rebek, Jr. research assistant 1974 UCLA (Chemistry Tree)
Robert B. Woodward grad student 1977 Harvard (Chemistry Tree)

Children

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Lee Keem Hoong grad student 1989 MIT (Chemistry Tree)
Thomas D Bannister grad student 1991 Indiana University (Chemistry Tree)
Michael S. VanNieuwenhze grad student 1992 Indiana University (Chemistry Tree)
Sherry R. Chemler grad student 1994-1999 Indiana University (Chemistry Tree)
Karl A. Scheidt grad student 1994-1999 Indiana University (Chemistry Tree)
Chad Edward Bennett grad student 2000 Indiana University (Chemistry Tree)
Garrett J. Dilley grad student 2000 University of Michigan (Chemistry Tree)
Lance Allen Pfeifer grad student 2000 Indiana University (Chemistry Tree)
Alejandro Álvarez Hernández grad student 2001 Indiana University (Chemistry Tree)
Scott Alan Frank grad student 2001 Indiana University (Chemistry Tree)
Gregory Curtis Lane grad student 2001 Indiana University (Chemistry Tree)
Glenn Christopher Micalizio grad student 2001 University of Michigan (Chemistry Tree)
Jason S. Newcom grad student 2002 University of Michigan (Chemistry Tree)
Bradley M. Savall grad student 2002 University of Michigan (Chemistry Tree)
William John Smith grad student 2002 University of Michigan (Chemistry Tree)
Cory Dene Emal grad student 2003 University of Michigan (Chemistry Tree)
Edward B. Holson grad student 2003 University of Michigan (Chemistry Tree)
Roxanne Kay Kunz grad student 2003 University of Michigan (Chemistry Tree)
Sridhar Narayan grad student 2003 University of Michigan (Chemistry Tree)
R. Jeffrey Neitz grad student 2003 University of Michigan (Chemistry Tree)
Neal A. Yakelis grad student 2003 University of Michigan (Chemistry Tree)
Eric M. Flamme grad student 2004 University of Michigan (Chemistry Tree)
Beth A. Knapp-Reed grad student 2004 University of Michigan (Chemistry Tree)
Dustin J. Mergott grad student 2004 University of Michigan (Chemistry Tree)
Thomas A. Dineen grad student 2005 University of Michigan (Chemistry Tree)
Lisa Deanna Julian grad student 2005 University of Michigan (Chemistry Tree)
Christopher M. Liu grad student 2005 University of Michigan (Chemistry Tree)
Scott A. Shaw grad student 2005 University of Michigan (Chemistry Tree)
Jennifer M. Tinsley grad student 2005 University of Michigan (Chemistry Tree)
Nan Zheng grad student 2000-2005 University of Michigan (Chemistry Tree)
Jungang Qin grad student 2006 University of Michigan (Neurotree)
Jun Qi grad student 2001-2006 University of Michigan (Chemistry Tree)
Gina M. Ney grad student 2007 University of Michigan (Chemistry Tree)
Robert H. Bates grad student 2009 Scripps Institute (Chemistry Tree)
Christine P. Nguyen grad student 2010 Scripps Institute (Chemistry Tree)
Geoff T. Halvorsen grad student 2012 Scripps Institute (Chemistry Tree)
John M. Whitaker grad student 2012 Scripps Institute (Chemistry Tree)
Yoshihiko Noguchi grad student 2012-2015 Scripps Research Institute Florida (Chemistry Tree)
Ryan L. Stowe grad student 2010-2016 TSRI (Chemistry Tree)
Roland Barth post-doc Scripps Research Institute Florida (Chemistry Tree)
Nicolas Blanchard post-doc University of Michigan (Chemistry Tree)
Karin Briner post-doc Indiana University (Chemistry Tree)
Darren Bykowski post-doc Scripps Research Institute Florida (Chemistry Tree)
Yen Ting Chen post-doc Scripps Research Institute Florida (Chemistry Tree)
Etzer Darout post-doc Scripps Research Institute Florida (Chemistry Tree)
Amy DeBaille post-doc Scripps Research Institute Florida (Chemistry Tree)
Joshua Dunetz post-doc Scripps Research Institute Florida (Chemistry Tree)
Masaki Handa post-doc Scripps Research Institute Florida (Chemistry Tree)
Jacqueline Hicks post-doc Scripps Research Institute Florida (Chemistry Tree)
Tamara Hopkins post-doc Scripps Research Institute Florida (Chemistry Tree)
Jeremy Kister post-doc Scripps Research Institute Florida (Chemistry Tree)
Andrew Martins post-doc Scripps Research Institute Florida (Chemistry Tree)
George Nora post-doc Scripps Research Institute Florida (Chemistry Tree)
Michael  Leroy Oberg post-doc Scripps Research Institute Florida (History of History Tree)
Troy Ryba post-doc Scripps Research Institute Florida (Chemistry Tree)
Achim Sorg post-doc Scripps Research Institute Florida (Chemistry Tree)
Huikai Sun post-doc Scripps Research Institute Florida (Chemistry Tree)
Reema Thalji post-doc Scripps Research Institute Florida (Chemistry Tree)
Mariola Tortosa post-doc Scripps Research Institute Florida (Chemistry Tree)
Fatima Basha post-doc 1979-1980 (Chemistry Tree)
Brigitte Lesur post-doc 1980-1982 (Chemistry Tree)
Thomas Caggiano post-doc 1983-1984 (Chemistry Tree)
Wesley K. Chong post-doc 1983-1984 (Chemistry Tree)
Sandra Russo-Rodriguez post-doc 1983-1986 MIT (Chemistry Tree)
Florenci V. González post-doc 1995-1998 Indiana University (Chemistry Tree)
Timothy B. Durham post-doc 2002-2004 University of Michigan (Chemistry Tree)
Robert Allen Owens post-doc 2003-2005 Scripps Research Institute Florida (Neurotree)
Brad Shotwell post-doc 2003-2005 Scripps Research Institute Florida (Chemistry Tree)
William T Lambert post-doc 2004-2006 University of Michigan (Chemistry Tree)
Ronald J. Rahaim, Jr. post-doc 2007-2011 Scripps Research Institute Florida (Chemistry Tree)
Fenzheng Li post-doc 2008-2012 Scripps Research Institute Florida (Chemistry Tree)
Julie Geist post-doc 2011-2012 Scripps Research Institute Florida (Chemistry Tree)
Philippe Nuhant post-doc 2009-2013 Scripps Research Institute Florida (Chemistry Tree)
Andy Tsai post-doc 2010-2013 Scripps Research Institute Florida (Chemistry Tree)
Christophe Allais post-doc 2011-2014 Scripps Research Institute Florida (Chemistry Tree)
Souad Ouizem post-doc 2011-2014 Scripps Research Institute Florida (Chemistry Tree)
Deboprosad Mondal post-doc 2011-2015 Scripps Research Institute Florida (Chemistry Tree)
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Publications

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Choi JY, Noguchi Y, Alburger JM, et al. (2023) Structure-Based Development of Isoform-Selective Inhibitors of Casein Kinase 1ε vs Casein Kinase 1δ. Journal of Medicinal Chemistry
Shahoei R, Pangeni S, Sanders MA, et al. (2022) Molecular Modeling of ABHD5 Structure and Ligand Recognition. Frontiers in Molecular Biosciences. 9: 935375
Jílková A, Rubešová P, Fanfrlík J, et al. (2020) Druggable Hot Spots in the Schistosomiasis Cathepsin B1 Target Identified by Functional and Binding Mode Analysis of Potent Vinyl Sulfone Inhibitors. Acs Infectious Diseases
Doebelin C, He Y, Campbell S, et al. (2019) Discovery and optimization of a series of sulfonamide inverse agonists for the retinoic acid receptor-related receptor-α. Medicinal Chemistry (Shariqah (United Arab Emirates))
Mahmud I, Tian G, Wang J, et al. (2019) Abstract 4718: SR-4370, a potent and selective inhibitor of class I HDACs, suppresses AR signaling and in vivo prostate tumor growth Cancer Research
Zyserman I, Mondal D, Sarabia F, et al. (2018) Identification of cysteine protease inhibitors as new drug leads against Naegleria fowleri. Experimental Parasitology
Tian G, Mahmud I, Stowe R, et al. (2018) Abstract B004: A combination of two chemically distinct inhibitors of class I HDACs is highly effective to suppress AR signaling and in vivo growth of prostate cancer xenograft Cancer Research. 78
Mahmud I, Garrett TJ, Stowe R, et al. (2018) Abstract LB-248: Chemically distinct class I HDAC inhibitors synergize to inhibit global lipid metabolism in cancer Cancer Research. 78
Monastyrskyi A, Nilchan N, Quereda V, et al. (2017) Development of dual casein kinase 1δ/1ε (CK1δ/ε) inhibitors for treatment of breast cancer. Bioorganic & Medicinal Chemistry
Rondini EA, Mladenovic-Lucas L, Roush WR, et al. (2017) Novel pharmacological probes reveal ABHD5 as a locus of lipolysis control in white and brown adipocytes. The Journal of Pharmacology and Experimental Therapeutics
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