Carol A. Fierke, Ph. D.

Affiliations:

Chemistry, Biological chemsitry

University of Michigan, Ann Arbor, Ann Arbor, MI

Area:

Enzymology, metalloenzymes, ribozyme, RNA

Website:

http://www.lsa.umich.edu/chem/people/faculty/fierkecarol_ci

Google:

"Carol A. Fierke"

Bio:

http://www.umich.edu/~caflab/caf.htm
http://www.nano.med.umich.edu/Members/Fierke.html

Cross-listing: Chemistry Tree

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Parents

William P. Jencks	grad student	1984	Brandeis (Chemistry Tree)
(Utilization of CoA binding energy for catalysis and effect of salts and buffers on a proton transfer reaction from fumarase to solvent)
Stephen J. Benkovic	post-doc		Penn State (Chemistry Tree)

Children

Jane E. Jackman	grad student	1999	Duke (Chemistry Tree)
Sharon McGee Crary	grad student	1993-1999	Duke (Chemistry Tree)
Jeffrey C. Kurz	grad student	2001	Duke (Chemistry Tree)
Jennifer S. Pickett	grad student	2003	University of Michigan (Chemistry Tree)
Laura Michele Rozan	grad student	2003	University of Michigan (Neurotree)
Jeremy J. Day	grad student	2004	University of Michigan (Chemistry Tree)
Heather L. Hartman	grad student	2005	University of Michigan (Chemistry Tree)
Katherine A. Hicks	grad student	2005	University of Michigan (Chemistry Tree)
Nissa M. Westerberg	grad student	2005	University of Michigan (Chemistry Tree)
Andrew J. Andrews	grad student	2006	University of Michigan (Chemistry Tree)
Stephanie L. Gantt	grad student	2006	University of Michigan (Chemistry Tree)
Manoj Cheriyan	grad student	2007	University of Michigan (Chemistry Tree)
Rebekah A. Kelly	grad student	2007	University of Michigan (Chemistry Tree)
June E. Pais	grad student	2007	University of Michigan (Chemistry Tree)
Jean K. Smith-Koutmos	grad student	2009	University of Michigan (Chemistry Tree)
Anette Casiano-Negroni	grad student	2010	University of Michigan (Chemistry Tree)
Samuel G. Gattis	grad student	2010	University of Michigan (Chemistry Tree)
Tamiika K. Hurst	grad student	2010	University of Michigan (Chemistry Tree)
Xiaomu Guan	grad student	2011	University of Michigan (Chemistry Tree)
Wan H. Lim	grad student	2011	University of Michigan (Chemistry Tree)
Caleb G. Joseph	grad student	2012	University of Michigan (Chemistry Tree)
Corissa L. Lamphear	grad student	2012	University of Michigan (Chemistry Tree)
Da Wang	grad student	2012	University of Michigan (Chemistry Tree)
Xin Liu	grad student	2007-2013	University of Michigan (Chemistry Tree)
Yu Chen	grad student	2010-2015	University of Michigan (Chemistry Tree)
Bradley P. Klemm	grad student	2012-2017	University of Michigan (Chemistry Tree)
Jeffrey E. Lopez	grad student	2012-2017	University of Michigan (Chemistry Tree)
Matthew Saderholm	post-doc	1998-1999	Duke University School of Medicine (Chemistry Tree)
James L. Hougland	post-doc	2005-2010	University of Michigan (Chemistry Tree)

Collaborators

Ayyalusamy Ramamoorthy

collaborator

Texas A & M

BETA: Related publications

Publications

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Wu Meyers N, Karasik A, Kaitany K, et al. (2022) Gambogic acid and juglone inhibit RNase P through distinct mechanisms. The Journal of Biological Chemistry. 102683
Si D, Nie G, Hurst TK, et al. (2021) Combining Active Carbonic Anhydrase with Nanogels: Enzyme Protection and Zinc Sensing. International Journal of Nanomedicine. 16: 6645-6660
Teramoto T, Kaitany KJ, Kakuta Y, et al. (2020) Pentatricopeptide repeats of protein-only RNase P use a distinct mode to recognize conserved bases and structural elements of pre-tRNA. Nucleic Acids Research
Sahoo BR, Bekier ME, Liu Z, et al. (2019) Structural Interaction of Apolipoprotein A-I Mimetic Peptide with Amyloid-β Generates Toxic Hetero-oligomers. Journal of Molecular Biology
Welker Leng K, Castaneda CA, Decroos C, et al. (2019) Phosphorylation of Histone Deacetylase 8: Structural and Mechanistic Analysis of Phosphomimetic S39E Mutant. Biochemistry
Karasik A, Fierke CA, Koutmos M. (2019) Interplay between substrate recognition, 5' end tRNA processing and methylation activity of human mitochondrial RNase P. Rna (New York, N.Y.)
García-Torres D, Fierke CA. (2019) The chaperone SmgGDS-607 has a dual role, both activating and inhibiting farnesylation of small GTPases. The Journal of Biological Chemistry
Sahoo BR, Genjo T, Nakayama TW, et al. (2019) A cationic polymethacrylate-copolymer acts as an agonist for β-amyloid and an antagonist for amylin fibrillation. Chemical Science. 10: 3976-3986
Sahoo BR, Genjo T, Bekier M, et al. (2018) Alzheimer's amyloid-beta intermediates generated using polymer-nanodiscs. Chemical Communications (Cambridge, England)
Sahoo BR, Genjo T, Cox SJ, et al. (2018) Nanodisc-Forming Scaffold Protein Promoted Retardation of Amyloid-Beta Aggregation. Journal of Molecular Biology