Mark R. Denison

Affiliations: 
Vanderbilt University, Nashville, TN 
Area:
Microbiology
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"Mark Denison"

Children

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Anne G. Bost grad student 2000 Vanderbilt
Amy C. Sims grad student 2001 Vanderbilt
Erik Prentice grad student 2004 Vanderbilt
Sarah B. McDonald grad student 2005 Vanderbilt
Rachel L. Graham grad student 2006 Vanderbilt
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Publications

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Grimes SL, Heaton BE, Anderson ML, et al. (2025) The coronavirus nsp14 exoribonuclease interface with the cofactor nsp10 is essential for efficient virus replication and enzymatic activity. Journal of Virology. e0170824
Abiona OM, Wang N, Leist SR, et al. (2024) MERS-CoV spike vaccine-induced N-terminal domain-specific antibodies are more protective than receptor binding domain-specific antibodies. Iscience. 28: 111632
Zhou NE, Tang S, Bian X, et al. (2024) An oral non-covalent non-peptidic inhibitor of SARS-CoV-2 Mpro ameliorates viral replication and pathogenesis in vivo. Cell Reports. 43: 114929
Grimes SL, Heaton BE, Anderson ML, et al. (2024) The coronavirus nsp14 exoribonuclease interface with the cofactor nsp10 is essential for efficient virus replication and enzymatic activity. Biorxiv : the Preprint Server For Biology
Grimes SL, Denison MR. (2024) The Coronavirus helicase in replication. Virus Research. 346: 199401
Grimes SL, Choi YJ, Banerjee A, et al. (2023) A mutation in the coronavirus nsp13-helicase impairs enzymatic activity and confers partial remdesivir resistance. Mbio. e0106023
Cable J, Denison MR, Kielian M, et al. (2023) Positive-strand RNA viruses-a Keystone Symposia report. Annals of the New York Academy of Sciences
Anderson-Daniels J, Gribble J, Denison M. (2022) Proteolytic Processing of the Coronavirus Replicase Nonstructural Protein 14 Exonuclease Is Not Required for Virus Replication but Alters RNA Synthesis and Viral Fitness. Journal of Virology. 96: e0084122
Stevens LJ, Pruijssers AJ, Lee HW, et al. (2022) Mutations in the SARS-CoV-2 RNA dependent RNA polymerase confer resistance to remdesivir by distinct mechanisms. Science Translational Medicine. eabo0718
Smith SC, Gribble J, Diller JR, et al. (2021) Reovirus RNA recombination is sequence directed and generates internally deleted defective genome segments during passage. Journal of Virology
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