Samuel K. Maheswaran

Affiliations: 
University of Minnesota, Twin Cities, Minneapolis, MN 
Area:
Molecular Biology, Veterinary Science, Cell Biology, Microbiology
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"Samuel Maheswaran"

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Samithamby Jeyaseelan grad student 2001 UMN
Praveen Thumbikat grad student 2004 UMN
Thamotharampillai Dileepan grad student 2006 UMN
Christie Ward grad student 2009 UMN
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Publications

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Dassanayake RP, Maheswaran SK, Srikumaran S. (2007) Monomeric expression of bovine beta2-integrin subunits reveals their role in Mannheimia haemolytica leukotoxin-induced biological effects. Infection and Immunity. 75: 5004-10
Dileepan T, Kachlany SC, Balashova NV, et al. (2007) Human CD18 is the functional receptor for Aggregatibacter actinomycetemcomitans leukotoxin. Infection and Immunity. 75: 4851-6
Dileepan T, Kannan MS, Walcheck B, et al. (2007) Integrin-EGF-3 domain of bovine CD18 is critical for Mannheimia haemolytica leukotoxin species-specific susceptibility. Fems Microbiology Letters. 274: 67-72
Thumbikat P, Dileepan T, Kannan MS, et al. (2005) Characterization of Mannheimia (Pasteurella) haemolytica leukotoxin interaction with bovine alveolar macrophage beta2 integrins. Veterinary Research. 36: 771-86
Dileepan T, Kannan MS, Walcheck B, et al. (2005) Mapping of the binding site for Mannheimia haemolytica leukotoxin within bovine CD18. Infection and Immunity. 73: 5233-7
Dileepan T, Thumbikat P, Walcheck B, et al. (2005) Recombinant expression of bovine LFA-1 and characterization of its role as a receptor for Mannheimia haemolytica leukotoxin. Microbial Pathogenesis. 38: 249-57
Thumbikat P, Dileepan T, Kannan MS, et al. (2005) Mechanisms underlying Mannheimia haemolytica leukotoxin-induced oncosis and apoptosis of bovine alveolar macrophages. Microbial Pathogenesis. 38: 161-72
Malazdrewich C, Thumbikat P, Maheswaran SK. (2004) Protective effect of dexamethasone in experimental bovine pneumonic mannheimiosis. Microbial Pathogenesis. 36: 227-36
Malazdrewich C, Thumbikat P, Abrahamsen MS, et al. (2004) Pharmacological inhibition of Mannheimia haemolytica lipopolysaccharide and leukotoxin-induced cytokine expression in bovine alveolar macrophages. Microbial Pathogenesis. 36: 159-69
Thumbikat P, Briggs RE, Kannan MS, et al. (2003) Biological effects of two genetically defined leukotoxin mutants of Mannheimia haemolytica. Microbial Pathogenesis. 34: 217-26
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