Aaron A. Tobian, Ph.D.
Affiliations: | 2004 | Case Western Reserve University School of Medicine, Cleveland, OH, United States |
Area:
Immunology, MicrobiologyGoogle:
"Aaron Tobian"Parents
Sign in to add mentor| Clifford V. Harding | grad student | 2004 | Case Western Medical School | |
| (MHC-II and alternate MHC-I antigen processing is inhibited by TLR-signaling PAMPs (Mycobacterium tuberculosis 19-kDa lipoprotein, CpG DNA and LPS), but enhanced by bacterial heat shock proteins.) | ||||
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Publications
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| Tobian AA, Harding CV, Canaday DH. (2005) Mycobacterium tuberculosis heat shock fusion protein enhances class I MHC cross-processing and -presentation by B lymphocytes. Journal of Immunology (Baltimore, Md. : 1950). 174: 5209-14 |
| Pai RK, Pennini ME, Tobian AA, et al. (2004) Prolonged toll-like receptor signaling by Mycobacterium tuberculosis and its 19-kilodalton lipoprotein inhibits gamma interferon-induced regulation of selected genes in macrophages. Infection and Immunity. 72: 6603-14 |
| Tobian AA, Canaday DH, Harding CV. (2004) Bacterial heat shock proteins enhance class II MHC antigen processing and presentation of chaperoned peptides to CD4+ T cells. Journal of Immunology (Baltimore, Md. : 1950). 173: 5130-7 |
| Tobian AA, Canaday DH, Boom WH, et al. (2004) Bacterial heat shock proteins promote CD91-dependent class I MHC cross-presentation of chaperoned peptide to CD8+ T cells by cytosolic mechanisms in dendritic cells versus vacuolar mechanisms in macrophages. Journal of Immunology (Baltimore, Md. : 1950). 172: 5277-86 |
| Tobian AA, Potter NS, Ramachandra L, et al. (2003) Alternate class I MHC antigen processing is inhibited by Toll-like receptor signaling pathogen-associated molecular patterns: Mycobacterium tuberculosis 19-kDa lipoprotein, CpG DNA, and lipopolysaccharide. Journal of Immunology (Baltimore, Md. : 1950). 171: 1413-22 |
| Chu RS, Askew D, Noss EH, et al. (1999) CpG oligodeoxynucleotides down-regulate macrophage class II MHC antigen processing. Journal of Immunology (Baltimore, Md. : 1950). 163: 1188-94 |