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Daniel H. Ebert, Ph.D.

Affiliations: 
2004 Vanderbilt University, Nashville, TN 
Area:
Microbiology
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"Daniel Ebert"
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Terence S. Dermody grad student 2004 Vanderbilt
 (Endocytic proteases and reovirus entry.)

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Crawford ED, Quan J, Horst JA, et al. (2017) Plasmid-free CRISPR/Cas9 genome editing in Plasmodium falciparum confirms mutations conferring resistance to the dihydroisoquinolone clinical candidate SJ733. Plos One. 12: e0178163
Jiménez-Díaz MB, Ebert D, Salinas Y, et al. (2014) (+)-SJ733, a clinical candidate for malaria that acts through ATP4 to induce rapid host-mediated clearance of Plasmodium. Proceedings of the National Academy of Sciences of the United States of America. 111: E5455-62
Lee FY, Faivre EJ, Suzawa M, et al. (2011) Eliminating SF-1 (NR5A1) sumoylation in vivo results in ectopic hedgehog signaling and disruption of endocrine development. Developmental Cell. 21: 315-27
Clark KM, Wetzel JD, Gu Y, et al. (2006) Reovirus variants selected for resistance to ammonium chloride have mutations in viral outer-capsid protein sigma3. Journal of Virology. 80: 671-81
Ebert DH, Kopecky-Bromberg SA, Dermody TS. (2004) Cathepsin B Is Inhibited in Mutant Cells Selected during Persistent Reovirus Infection. The Journal of Biological Chemistry. 279: 3837-51
Barton ES, Youree BE, Ebert DH, et al. (2003) Utilization of sialic acid as a coreceptor is required for reovirus-induced biliary disease. The Journal of Clinical Investigation. 111: 1823-33
Wilson GJ, Nason EL, Hardy CS, et al. (2002) A single mutation in the carboxy terminus of reovirus outer-capsid protein sigma 3 confers enhanced kinetics of sigma 3 proteolysis, resistance to inhibitors of viral disassembly, and alterations in sigma 3 structure. Journal of Virology. 76: 9832-43
Ebert DH, Deussing J, Peters C, et al. (2002) Cathepsin L and cathepsin B mediate reovirus disassembly in murine fibroblast cells. The Journal of Biological Chemistry. 277: 24609-17
Ebert DH, Wetzel JD, Brumbaugh DE, et al. (2001) Adaptation of reovirus to growth in the presence of protease inhibitor E64 segregates with a mutation in the carboxy terminus of viral outer-capsid protein sigma3. Journal of Virology. 75: 3197-206
Baer GS, Ebert DH, Chung CJ, et al. (1999) Mutant cells selected during persistent reovirus infection do not express mature cathepsin L and do not support reovirus disassembly. Journal of Virology. 73: 9532-43
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