Deborah Silvera, Ph.D.
Affiliations: | 2000 | University of California, San Francisco, San Francisco, CA |
Area:
Cell Biology, MicrobiologyGoogle:
"Deborah Silvera"Parents
Sign in to add mentor| Raul Andino | grad student | 2000 | UCSF | |
| (Aspects of poliovirus replication: Characterization of the structural and functional interaction between the poly(rC) binding protein and the viral RNA and effects of genomic insertions on the assembly pathway.) | ||||
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Publications
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| Silvera D, Ernlund A, Arju R, et al. (2016) mTORC1 and 2 coordinate transcriptional and translational reprogramming in resistance to DNA damage and replicative stress in breast cancer cells. Molecular and Cellular Biology |
| Jhaveri K, Teplinsky E, Silvera D, et al. (2015) Hyperactivated mTOR and JAK2/STAT3 Pathways: Molecular Drivers and Potential Therapeutic Targets of Inflammatory and Invasive Ductal Breast Cancers After Neoadjuvant Chemotherapy. Clinical Breast Cancer |
| Jhaveri KL, Teplinsky E, Arju R, et al. (2013) Hyperactivated mTOR and JAK2/STAT3 pathways: Crucial molecular drivers and potential therapeutic targets of inflammatory breast cancer (IBC). Journal of Clinical Oncology. 31: 11106-11106 |
| Silvera D, Connolly E, Volta V, et al. (2012) Abstract P5-03-02: Targeting mRNA Translation to Enhance the Radiosensitivity of Inflammatory Breast Cancer Stem Cells Cancer Research. 72 |
| Connolly E, Silvera D, Badura M, et al. (2011) Over-expression of Translation Initiation Factor eIF4G Confers Robust Radioresistance to the Cancer Stem Cell Population in Inflammatory Breast Cancer International Journal of Radiation Oncology*Biology*Physics. 81: S85 |
| Connolly E, Silvera D, Venuto T, et al. (2011) TORC1/2 Inhibition with Concurrent Radiation Controls Inflammatory Breast Cancer in a Preclinical Animal Model Through Selective Blockade of Translation International Journal of Radiation Oncology*Biology*Physics. 81: S751 |
| Silvera D, Formenti SC, Schneider RJ. (2010) Translational control in cancer. Nature Reviews. Cancer. 10: 254-66 |
| Connolly E, Silvera D, Formenti S, et al. (2010) Abstract P5-06-05: Catalytic mTOR Inhibition with pp242 but Not Allosteric Inhibition with Rapamycin RAD001 Enhances the Radiosensitivity of Inflammatory Breast Cancer in an Animal Model Cancer Research. 70 |
| Connolly E, Silvera D, Badura M, et al. (2010) Inflammatory Breast Cancer Radio-resistance and its Cancer Stem Cell Population are Oppositely Controlled by Translation Factor eIF4G International Journal of Radiation Oncology*Biology*Physics. 78: S221 |
| Silvera D, Schneider RJ. (2009) Inflammatory breast cancer cells are constitutively adapted to hypoxia. Cell Cycle (Georgetown, Tex.). 8: 3091-6 |