Collin J. LaCasse, Ph.D.

Affiliations: 
2011 Immunobiology University of Arizona, Tucson, AZ 
Area:
Immunology, Oncology
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"Collin LaCasse"

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Emmanuel Katsanis grad student 2011 University of Arizona
 (Negative modulation of regulatory T cells and promotion of the tumoricidal activity of dendritic cells in cancer: A double-edged strategy.)
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Publications

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Trad M, Gautheron A, Fraszczak J, et al. (2015) T Lymphocyte Inhibition by Tumor-Infiltrating Dendritic Cells Involves Ectonucleotidase CD39 but Not Arginase-1. Biomed Research International. 2015: 891236
Hanke NT, LaCasse CJ, Larmonier CB, et al. (2014) PIAS1 and STAT-3 impair the tumoricidal potential of IFN-γ-stimulated mouse dendritic cells generated with IL-15. European Journal of Immunology. 44: 2489-99
Centuori SM, Trad M, LaCasse CJ, et al. (2012) Myeloid-derived suppressor cells from tumor-bearing mice impair TGF-β-induced differentiation of CD4+CD25+FoxP3+ Tregs from CD4+CD25-FoxP3- T cells. Journal of Leukocyte Biology. 92: 987-97
LaCasse CJ, Janikashvili N, Larmonier CB, et al. (2011) Th-1 lymphocytes induce dendritic cell tumor killing activity by an IFN-γ-dependent mechanism. Journal of Immunology (Baltimore, Md. : 1950). 187: 6310-7
Janikashvili N, LaCasse CJ, Larmonier C, et al. (2011) Allogeneic effector/memory Th-1 cells impair FoxP3+ regulatory T lymphocytes and synergize with chaperone-rich cell lysate vaccine to treat leukemia. Blood. 117: 1555-64
Larmonier N, Janikashvili N, LaCasse CJ, et al. (2008) Imatinib mesylate inhibits CD4+ CD25+ regulatory T cell activity and enhances active immunotherapy against BCR-ABL- tumors. Journal of Immunology (Baltimore, Md. : 1950). 181: 6955-63
Golden JM, LaCasse CJ, Simova DV, et al. (2008) Differential mediator production by dendritic cells upon toll-like receptor stimulation does not impact T cell cytokine expression. Immunology Letters. 118: 30-5
Larmonier N, Cantrell J, Lacasse C, et al. (2008) Chaperone-rich tumor cell lysate-mediated activation of antigen-presenting cells resists regulatory T cell suppression. Journal of Leukocyte Biology. 83: 1049-59
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