Salil A. Lachke, Ph.D.

Affiliations: 
2011- Department of Biological Sciences University of Delaware, Newark, DE, United States 
Area:
Biology
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"Salil Lachke"

Parents

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David R. Soll grad student 1997-2003 University of Iowa
 (Developmental biology of Candida albicans and Candida glabrata and its clinical significance.)
Richard L. Maas post-doc 2003-2010 Harvard Medical School
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Publications

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Tangeman JA, Rebull SM, Grajales-Esquivel E, et al. (2024) Integrated single-cell multiomics uncovers foundational regulatory mechanisms of lens development and pathology. Development (Cambridge, England). 151
Duot M, Viel R, Viet J, et al. (2023) Eye Lens Organoids Made Simple: Characterization of a New Three-Dimensional Organoid Model for Lens Development and Pathology. Cells. 12
Duot M, Viel R, Viet J, et al. (2023) Eye lens organoids going simple: characterization of a new 3-dimensional organoid model for lens development and pathology. Biorxiv : the Preprint Server For Biology
Tangeman JA, Rebull SM, Grajales-Esquivel E, et al. (2023) Integrated single-cell multiomics uncovers foundational regulatory mechanisms of lens development and pathology. Biorxiv : the Preprint Server For Biology
Aryal S, Anand D, Huang H, et al. (2023) Proteomic profiling of retina and retinal pigment epithelium combined embryonic tissue to facilitate ocular disease gene discovery. Human Genetics
Siddam AD, Duot M, Coomson SY, et al. (2023) High-Throughput Transcriptomics of Conditional Knockout Lens Identifies Downstream Networks Linked to Cataract Pathology. Cells. 12
Aryal S, Anand D, Huang H, et al. (2023) Proteomic profiling of retina and retinal pigment epithelium combined embryonic tissue to facilitate ocular disease gene discovery. Research Square
Upreti A, Padula SL, Tangeman JA, et al. (2023) Lens Epithelial Explants Treated with Vitreous Humor Undergo Alterations in Chromatin Landscape with Concurrent Activation of Genes Associated with Fiber Cell Differentiation and Innate Immune Response. Cells. 12
Patel SD, Anand D, Motohashi H, et al. (2022) Deficiency of the bZIP transcription factors Mafg and Mafk causes misexpression of genes in distinct pathways and results in lens embryonic developmental defects. Frontiers in Cell and Developmental Biology. 10: 981893
Lachke SA. (2021) RNA-binding proteins and post-transcriptional regulation in lens biology and cataract: Mediating spatiotemporal expression of key factors that control the cell cycle, transcription, cytoskeleton and transparency. Experimental Eye Research. 214: 108889
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