Kwang H. Ahn, Ph.D.
Affiliations: | 2009 | University of Connecticut, Storrs, CT, United States |
Area:
BiochemistryGoogle:
"Kwang Ahn"Parents
Sign in to add mentor| Debra A. Kendall | grad student | 2009 | University of Connecticut | |
| (Structural and functional characterization of the cannabinoid receptor one: Roles for two non-transmembrane domains, the second extracellular loop and carboxyl terminus.) | ||||
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| Tahtouh T, Durieu E, Villiers B, et al. (2021) Structure-Activity Relationship in the Leucettine Family of Kinase Inhibitors. Journal of Medicinal Chemistry |
| Qiao CJ, Ali HI, Ahn KH, et al. (2016) Synthesis and biological evaluation of indole-2-carboxamides bearing photoactivatable functionalities as novel allosteric modulators for the cannabinoid CB1 receptor. European Journal of Medicinal Chemistry. 121: 517-529 |
| Delgado-Peraza F, Ahn K, Nogueras-Ortiz C, et al. (2016) Mechanisms of biased beta-arrestin mediated signaling downstream from the cannabinoid 1 receptor. Molecular Pharmacology |
| Scott C, Ahn KH, Graf ST, et al. (2015) Computational Prediction and Biochemical Analyses of New Inverse Agonists for the CB1 Receptor. Journal of Chemical Information and Modeling |
| Flores-Otero J, Ahn KH, Delgado-Peraza F, et al. (2014) Ligand-specific endocytic dwell times control functional selectivity of the cannabinoid receptor 1. Nature Communications. 5: 4589 |
| Khurana L, Ali HI, Olszewska T, et al. (2014) Optimization of chemical functionalities of indole-2-carboxamides to improve allosteric parameters for the cannabinoid receptor 1 (CB1). Journal of Medicinal Chemistry. 57: 3040-52 |
| Shim JY, Ahn KH, Kendall DA. (2013) Molecular basis of cannabinoid CB1 receptor coupling to the G protein heterotrimer Gαiβγ: identification of key CB1 contacts with the C-terminal helix α5 of Gαi. The Journal of Biological Chemistry. 288: 32449-65 |
| Mahmoud MM, Ali HI, Ahn KH, et al. (2013) Structure-activity relationship study of indole-2-carboxamides identifies a potent allosteric modulator for the cannabinoid receptor 1 (CB1). Journal of Medicinal Chemistry. 56: 7965-75 |
| Ahn KH, Mahmoud MM, Shim JY, et al. (2013) Distinct roles of β-arrestin 1 and β-arrestin 2 in ORG27569-induced biased signaling and internalization of the cannabinoid receptor 1 (CB1). The Journal of Biological Chemistry. 288: 9790-800 |
| Ahn KH, Scott CE, Abrol R, et al. (2013) Computationally-predicted CB1 cannabinoid receptor mutants show distinct patterns of salt-bridges that correlate with their level of constitutive activity reflected in G protein coupling levels, thermal stability, and ligand binding. Proteins. 81: 1304-17 |