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Hannah Alexander

Affiliations: 
University of Missouri - Columbia, Columbia, MO, United States 
Area:
Cell Biology, Microbiology Biology
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"Hannah Alexander"
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Guochun Li grad student 2000 University of Missouri - Columbia
Supriya Srinivasan grad student 2000 University of Missouri - Columbia

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Publications

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Alexander S, Swatson WS, Alexander H. (2013) Pharmacogenetics of resistance to Cisplatin and other anticancer drugs and the role of sphingolipid metabolism. Methods in Molecular Biology (Clifton, N.J.). 983: 185-204
Alexander S, Alexander H. (2011) Lead genetic studies in Dictyostelium discoideum and translational studies in human cells demonstrate that sphingolipids are key regulators of sensitivity to cisplatin and other anticancer drugs. Seminars in Cell & Developmental Biology. 22: 97-104
Sridevi P, Alexander H, Laviad EL, et al. (2010) Stress-induced ER to Golgi translocation of ceramide synthase 1 is dependent on proteasomal processing. Experimental Cell Research. 316: 78-91
Sridevi P, Alexander H, Laviad EL, et al. (2009) Ceramide synthase 1 is regulated by proteasomal mediated turnover. Biochimica Et Biophysica Acta. 1793: 1218-27
Van Driessche N, Alexander H, Min J, et al. (2007) Global transcriptional responses to cisplatin in Dictyostelium discoideum identify potential drug targets. Proceedings of the National Academy of Sciences of the United States of America. 104: 15406-11
Min J, Mesika A, Sivaguru M, et al. (2007) (Dihydro)ceramide synthase 1 regulated sensitivity to cisplatin is associated with the activation of p38 mitogen-activated protein kinase and is abrogated by sphingosine kinase 1. Molecular Cancer Research : McR. 5: 801-12
Min J, Van Veldhoven PP, Zhang L, et al. (2005) Sphingosine-1-phosphate lyase regulates sensitivity of human cells to select chemotherapy drugs in a p38-dependent manner. Molecular Cancer Research : McR. 3: 287-96
Min J, Traynor D, Stegner AL, et al. (2005) Sphingosine kinase regulates the sensitivity of Dictyostelium discoideum cells to the anticancer drug cisplatin. Eukaryotic Cell. 4: 178-89
Min J, Stegner AL, Alexander H, et al. (2004) Overexpression of sphingosine-1-phosphate lyase or inhibition of sphingosine kinase in Dictyostelium discoideum results in a selective increase in sensitivity to platinum-based chemotherapy drugs. Eukaryotic Cell. 3: 795-805
Alexander S, Srinivasan S, Alexander H. (2003) Proteomics opens doors to the mechanisms of developmentally regulated secretion. Molecular & Cellular Proteomics : McP. 2: 1156-63
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