R C. Bleackley
Affiliations: | University of Alberta, Edmonton, Alberta, Canada |
Area:
Biochemistry, Microbiology BiologyGoogle:
"R Bleackley"
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Publications
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| Saito A, Okiyama N, Kubota N, et al. (2018) Blockade of granzyme B remarkably improves mucocutaneous diseases with keratinocyte death in interface dermatitis. The Journal of Investigative Dermatology |
| Baginska J, Viry E, Berchem G, et al. (2013) Granzyme B degradation by autophagy decreases tumor cell susceptibility to natural killer-mediated lysis under hypoxia. Proceedings of the National Academy of Sciences of the United States of America. 110: 17450-5 |
| Ewen CL, Kane KP, Bleackley RC. (2013) Granzyme H induces cell death primarily via a Bcl-2-sensitive mitochondrial cell death pathway that does not require direct Bid activation. Molecular Immunology. 54: 309-18 |
| Ewen CL, Kane KP, Bleackley RC. (2012) A quarter century of granzymes. Cell Death and Differentiation. 19: 28-35 |
| Marcet-Palacios M, Duggan BL, Shostak I, et al. (2011) Granzyme B inhibits vaccinia virus production through proteolytic cleavage of eukaryotic initiation factor 4 gamma 3. Plos Pathogens. 7: e1002447 |
| Haile Y, Simmen KC, Pasichnyk D, et al. (2011) Granule-derived granzyme B mediates the vulnerability of human neurons to T cell-induced neurotoxicity. Journal of Immunology (Baltimore, Md. : 1950). 187: 4861-72 |
| Sutendra G, Dromparis P, Bonnet S, et al. (2011) Pyruvate dehydrogenase inhibition by the inflammatory cytokine TNFα contributes to the pathogenesis of pulmonary arterial hypertension. Journal of Molecular Medicine (Berlin, Germany). 89: 771-83 |
| Thiery J, Keefe D, Boulant S, et al. (2011) Perforin pores in the endosomal membrane trigger the release of endocytosed granzyme B into the cytosol of target cells. Nature Immunology. 12: 770-7 |
| Mader JS, Ewen C, Hancock RE, et al. (2011) The human cathelicidin, LL-37, induces granzyme-mediated apoptosis in regulatory T cells. Journal of Immunotherapy (Hagerstown, Md. : 1997). 34: 229-35 |
| Mader JS, Marcet-Palacios M, Hancock RE, et al. (2011) The human cathelicidin, LL-37, induces granzyme-mediated apoptosis in cytotoxic T lymphocytes. Experimental Cell Research. 317: 531-8 |