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Laty A. Cahoon, Ph.D.

Affiliations: 
2012 Integrated Graduate Program in the Life Sciences Northwestern University, Evanston, IL 
Area:
Microbiology Biology, Molecular Biology
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"Laty Cahoon"
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H. Steven Seifert grad student 2012 Northwestern
 (An Alternative DNA Structure is Required for Pilin Antigenic Variation in Neisseria gonorrhoeae.)

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Publications

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Prister LL, Yin S, Cahoon LA, et al. (2020) Altering the Guanine Quadruplex Loop Bases Affects Pilin Antigenic Variation. Biochemistry
Prister LL, Ozer EA, Cahoon LA, et al. (2019) Transcriptional initiation of a small RNA, not R-loop stability, dictates the frequency of pilin antigenic variation in Neisseria gonorrhoeae. Molecular Microbiology
Cahoon LA, Manthei KA, Rotman E, et al. (2013) Neisseria gonorrhoeae RecQ helicase HRDC domains are essential for efficient binding and unwinding of the pilE guanine quartet structure required for pilin antigenic variation. Journal of Bacteriology. 195: 2255-61
Cahoon LA, Seifert HS. (2013) Transcription of a cis-acting, noncoding, small RNA is required for pilin antigenic variation in Neisseria gonorrhoeae. Plos Pathogens. 9: e1003074
Kuryavyi V, Cahoon LA, Seifert HS, et al. (2012) RecA-binding pilE G4 sequence essential for pilin antigenic variation forms monomeric and 5' end-stacked dimeric parallel G-quadruplexes. Structure (London, England : 1993). 20: 2090-102
Cahoon LA, Seifert HS. (2011) Focusing homologous recombination: pilin antigenic variation in the pathogenic Neisseria. Molecular Microbiology. 81: 1136-43
Cahoon LA, Stohl EA, Seifert HS. (2011) The Neisseria gonorrhoeae photolyase orthologue phrB is required for proper DNA supercoiling but does not function in photo-reactivation. Molecular Microbiology. 79: 729-42
Cahoon LA, Seifert HS. (2009) An alternative DNA structure is necessary for pilin antigenic variation in Neisseria gonorrhoeae. Science (New York, N.Y.). 325: 764-7
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