James E. Laithwaite, Ph.D.

Affiliations: 
2002 University of Guelph (Canada), Guelph, Ontario, Canada 
Area:
Microbiology Biology
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"James Laithwaite"

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Jonathan LaMarre grad student 2002 University of Guelph (Canada)
 (Modulation of cellular Pseudomonas exotoxin A sensitivity through induced changes in toxin receptor expression.)
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Publications

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Yamate J, Maeda M, Benn SJ, et al. (2001) Differential effects of transforming growth factor-beta1, a fibrogenic factor, on macrophage-like cells (HS-P) and myofibroblastic cells (MT-9) in vitro. Toxicologic Pathology. 29: 483-91
Yamate J, Maeda M, Benn SJ, et al. (2001) Effects of lipopolysaccharide on a macrophage-like cell line (HS-P) from a rat histiocytic sarcoma. Journal of Comparative Pathology. 125: 15-24
Laithwaite JE, Benn SJ, Marshall WS, et al. (2001) Divergent Pseudomonas exotoxin A sensitivity in normal and transformed liver cells is correlated with low-density lipoprotein receptor-related protein expression. Toxicon : Official Journal of the International Society On Toxinology. 39: 1283-90
Yamate J, Maeda M, Tsukamoto Y, et al. (2001) Macrophage-like cell line (HS-P) from a rat histiocytic sarcoma. Journal of Comparative Pathology. 124: 183-91
Laithwaite JE, Benn SJ, Yamate J, et al. (1999) Enhanced macrophage resistance to Pseudomonas exotoxin A is correlated with decreased expression of the low-density lipoprotein receptor-related protein. Infection and Immunity. 67: 5827-33
Schmoelzl S, Benn SJ, Laithwaite JE, et al. (1998) Expression of hepatocyte low-density lipoprotein receptor-related protein is post-transcriptionally regulated by extracellular matrix. Laboratory Investigation; a Journal of Technical Methods and Pathology. 78: 1405-13
Benn SJ, Allan A, Laithwaite JE, et al. (1998) Effect of extracellular matrix on gene expression and mRNA stability in primary rat hepatocytes Journal of Toxicologic Pathology. 11: 219-227
Laithwaite JE, Benn SJ, Yamate J, et al. (1998) Increased resistance to Pseudomonas exotoxin a coincides with decreased LRP expression in HS-P macrophages Faseb Journal. 12
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