Edward Pearce

Affiliations: 
Cornell University, Ithaca, NY, United States 
Area:
Immunology, Microbiology Biology
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"Edward Pearce"
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Knoke K, Rongisch RR, Grzes KM, et al. (2021) Tofacitinib suppresses IL-10/IL-10R signaling and modulates host defense responses in human macrophages. The Journal of Investigative Dermatology
Stanczak MA, Sanin DE, Apostolova P, et al. (2021) IL-33 expression in response to SARS-CoV-2 correlates with seropositivity in COVID-19 convalescent individuals. Nature Communications. 12: 2133
Montes de Oca M, de Labastida Rivera F, Winterford C, et al. (2020) IL-27 signalling regulates glycolysis in Th1 cells to limit immunopathology during infection. Plos Pathogens. 16: e1008994
Everts B, Tussiwand R, Dreesen L, et al. (2015) Migratory CD103+ dendritic cells suppress helminth-driven type 2 immunity through constitutive expression of IL-12. The Journal of Experimental Medicine
Reese TA, Wakeman BS, Choi HS, et al. (2014) Coinfection. Helminth infection reactivates latent γ-herpesvirus via cytokine competition at a viral promoter. Science (New York, N.Y.). 345: 573-7
Perona-Wright G, Kohlmeier JE, Bassity E, et al. (2012) Persistent loss of IL-27 responsiveness in CD8+ memory T cells abrogates IL-10 expression in a recall response. Proceedings of the National Academy of Sciences of the United States of America. 109: 18535-40
Pearce EJ, Caspar P, Grzych JM, et al. (2012) Pillars article: downregulation of Th1 cytokine production accompanies induction of Th2 responses by a parasitic helminth, Schistosoma mansoni. J. Exp. Med. 1991. 173: 159-166. Journal of Immunology (Baltimore, Md. : 1950). 189: 1104-11
Fairfax KC, Amiel E, King IL, et al. (2012) IL-10R blockade during chronic schistosomiasis mansoni results in the loss of B cells from the liver and the development of severe pulmonary disease. Plos Pathogens. 8: e1002490
O'Connell AE, Kerepesi LA, Vandergrift GL, et al. (2009) IL-4(-/-) mice with lethal Mesocestoides corti infections--reduced Th2 cytokines and alternatively activated macrophages. Parasite Immunology. 31: 741-9
Glatman Zaretsky A, Taylor JJ, King IL, et al. (2009) T follicular helper cells differentiate from Th2 cells in response to helminth antigens. The Journal of Experimental Medicine. 206: 991-9
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