Wesley C. Van Voorhis

Affiliations: 
University of Washington, Seattle, Seattle, WA 
Area:
Microbiology Biology
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"Wesley Van Voorhis"
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Publications

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Jiménez-Meléndez A, Ojo KK, Wallace AM, et al. (2017) In vitro efficacy of bumped kinase inhibitors against Besnoitia besnoiti tachyzoites. International Journal For Parasitology
Ojo KK, Dangoudoubiyam S, Verma SK, et al. (2016) Selective inhibition of Sarcocystis neurona calcium-cependent protein kinase 1 for equine protozoal myeloencephalitis therapy. International Journal For Parasitology
Vidadala RS, Rivas KL, Ojo KK, et al. (2016) Development of an Orally Available and Central Nervous System (CNS) Penetrant Toxoplasma gondii Calcium-Dependent Protein Kinase 1 (TgCDPK1) Inhibitor with Minimal Human Ether-a-go-go-Related Gene (hERG) Activity for the Treatment of Toxoplasmosis. Journal of Medicinal Chemistry. 59: 6531-46
Winzer P, Müller J, Aguado-Martínez A, et al. (2015) In Vitro and In Vivo Effects of the Bumped Kinase Inhibitor 1294 in the Related Cyst-Forming Apicomplexans Toxoplasma gondii and Neospora caninum. Antimicrobial Agents and Chemotherapy. 59: 6361-74
Hines SA, Ramsay JD, Kappmeyer LS, et al. (2015) Theileria equi isolates vary in susceptibility to imidocarb dipropionate but demonstrate uniform in vitro susceptibility to a bumped kinase inhibitor. Parasites & Vectors. 8: 33
Ojo KK, Eastman RT, Vidadala R, et al. (2014) A specific inhibitor of PfCDPK4 blocks malaria transmission: chemical-genetic validation. The Journal of Infectious Diseases. 209: 275-84
Johnson SM, Murphy RC, Geiger JA, et al. (2012) Development of Toxoplasma gondii calcium-dependent protein kinase 1 (TgCDPK1) inhibitors with potent anti-toxoplasma activity. Journal of Medicinal Chemistry. 55: 2416-26
Shibata S, Gillespie JR, Kelley AM, et al. (2011) Selective inhibitors of methionyl-tRNA synthetase have potent activity against Trypanosoma brucei Infection in Mice. Antimicrobial Agents and Chemotherapy. 55: 1982-9
Ojo KK, Gillespie JR, Riechers AJ, et al. (2008) Glycogen synthase kinase 3 is a potential drug target for African trypanosomiasis therapy. Antimicrobial Agents and Chemotherapy. 52: 3710-7
Arakaki TL, Buckner FS, Gillespie JR, et al. (2008) Characterization of Trypanosoma brucei dihydroorotate dehydrogenase as a possible drug target; structural, kinetic and RNAi studies. Molecular Microbiology. 68: 37-50
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